Monday Night Football Odds & Predictions 2025: Ravens Host Lions on MNF Week 3
The Baltimore Ravens are as much as a 6-point betting favorite at home against the Detroit Lions by the Monday Night Football odds for the NFL's Week 3 finale at M&T Bank Stadium (8:15 p.m. ET, ESPN).
Our NFL predictions for Week 3 include Phil Wood's early Lions vs. Ravens prediction for this week's marquee game.
๐ MNF Week 3 odds: Lions vs. Ravens (-5.5)
The NFL odds for Week 3 swung in Baltimore's favor despite both teams being 1-1 and coming off an emphatic Week 2 victory. The Ravens opened as a 3.5-point betting favorite but are now laying 5.5 or 6 points, depending on your best sports betting sites.
Lions bettors should head to Caesars for a line of +6, while Ravens supporters can get a line of -5.5 at DraftKings. The Over/Under sits at a consensus of 51.5 points, and I'd expect that to rise through the week.
Live Lions vs. Ravens odds
Our NFL odds update in real time and show the best line/odds for either side of the spread, Over/Under, and moneyline:
๐ฎ Monday Night Football predictions
Here are our betting experts' NFL picks for the Monday Night Football:
Lions vs. Ravens MNF predictions:
Ravens -5.5 (-118) via C Jackson Cowart: "The Ravens open as a 5.5-point betting favorite over the Lions in a matchup between 1-1 teams coming off blowout wins last week. I trust what I've seen from Baltimore through the first two weeks more than I do for Detroit, which beat up on the Bears but could struggle to trade punches with Lamar Jackson and Co. in a tough road environment."
Lions +6 (-112) via Dustin Saracini: "I think giving Detroit close to a touchdown in any matchup is crazy work here by the books. Remember, while the Lions are just 1-1 against the spread this year, they were ATS darlings for bettors a year ago (12-6), and just consistently find a way to cover. After putting up over 50 points in Week 2 against the Bears, and the Ravens allowing close to 60 points through two weeks, I can see Detroit covering with ease in this one, if not winning outright."
Over 51.5 (-110) via Phil Wood: "These offenses combined for 93 points in Week 2, and considering both defenses have shown blemishes against good offenses, I'm expecting another very high-scoring game."
๐ Monday Night Football betting results
Here are the results of the spread and Over/Under from every completed Monday Night Football game this season:
| Week | Matchup | Spread | Over/Under |
|---|---|---|---|
| 1 | Vikings vs. Bears | Vikings +1.5 | O43.5 |
| 2 | Buccaneers vs. Texas | Buccaneers +2.5 | U42.5 |
| 2 | Chargers vs. Raiders | Chargers -3.5 | U46.5 |
๐๏ธ Monday Night Football 2025 schedule
Opening Monday Night Football NFL odds for the 2025 season regular season are via DraftKings.
| Week | Matcup | Opening spread | Opening Over/Under |
|---|---|---|---|
| 3 (Sept. 22) | Lions vs. Ravens | Ravens -3.5 | 49.5 |
| 4 (Sept. 29) | Jets vs. Dolphins | Dolphins -5.5 | 44.5 |
| 4 (Sept. 29) | Bengals vs. Broncos | Broncos -2.5 | 47.5 |
| 5 (Oct. 6) | Chiefs vs. Jaguars | Chiefs -4.5 | 47.5 |
| 6 (Oct. 13) | Bills vs. Falcons | Bills -5.5 | 48.5 |
| 6 (Oct. 13) | Bears vs. Commanders | Commanders -4.5 | 48.5 |
| 7 (Oct. 20) | Buccaneers vs. Lions | Lions -3.5 | 49.5 |
| 7 (Oct. 20) | Texans vs. Seahawks | Seahawks -1.5 | 44.5 |
| 8 (Oct. 27) | Commanders vs. Chiefs | Chiefs -3.5 | 48.5 |
| 9 (Nov. 3) | Cardinals vs. Cowboys | Cowboys -1.5 | 47.5 |
| 10 (Nov. 10) | Eagles vs. Packers | Eagles -1.5 | 45.5 |
| 11 (Nov. 17) | Cowboys vs. Raiders | Cowboys -1.5 | 45.5 |
| 12 (Nov. 24) | Panthers vs. 49ers | 49ers -7 | 46.5 |
| 13 (Dec. 1) | Giants vs. Patriots | Patriots -3 | 42.5 |
| 14 (Dec. 8) | Eagles vs. Chargers | Eagles -2.5 | 45.5 |
| 15 (Dec. 15) | Dolphins vs. Steelers | Steelers -2.5 | 44.5 |
| 16 (Dec. 22) | 49ers vs. Colts | 49ers -3 | 46.5 |
| 17 (Dec. 29) | Rams vs. Falcons | Rams -3 | 46.5 |
Don't miss our lists of the best NFL parlay betting sites and top NFL prop betting sites!
๐ง Monday Night Football betting tips
Get an early start
The Monday Night Football game is a big deal for betting each week. This brings lots of bets and changes in the odds, especially from those chasing their losses after a tough Sunday betting slate. Watch the lines and totals when they start. If they go the way you like, you can wait. If they move against you, think about acting sooner.
Embrace in-game betting
While you might struggle to find value in the most popular markets for any marquee prime-time NFL game, you're sure to unearth some worthwhile plays once the game starts. Live betting might not be your thing when there are a handful of games going on at the same time, but Monday Night Football is the perfect time to lay into some live action via our best live betting sites.
Be wary of winter weather
Things can get pretty frightful outside later in the NFL season โ particularly when the sun goes down. Our guide on how to bet on the NFL offers tips for how to approach betting on cold-weather games.
Check out our list of the best sportsbook promos here!
โMonday Night Football FAQs
Who is favored on Monday Night Football this week?
The Baltimore Ravens are favored by as much as 6 points across our best NFL betting sites in Monday Night Football against the Detroit Lions at M&T Bank Stadium.
How do I watch Sunday Night Football?
Monday Night Football is broadcast on ESPN with some doubleheaders appearing on ABC.
Who are the announcers on Monday Night Football?
Joe Buck and Troy Aikman are the current commentators for Monday Night Football on ESPN. Laura Rutledge and Lisa Salters are the sideline reporters, and Russell Yurk is the rules analyst on the broadcast.
Who will make the most Monday Night Football appearances in 2025?
No team will make more than two appearances on Monday Night Football season.
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