Early Seahawks vs. Cardinals Prediction, Odds & Picks for TNF: NFL Week 4
The Seattle Seahawks visit the Arizona Cardinals at State Farm Stadium in Glendale, Ariz., for Thursday Night Football (8:15 p.m. ET, Prime Video), and my early Seahawks vs. Cardinals prediction backs the underdog Seahawks.
My NFL picks for TNF highlight the primary reasons to jump on the Sam Darnold bandwagon, at least on this occasion. The Cardinals are the 1.5-point betting favorite, and this preview is part of the NFL predictions for Week 4.
Early Seahawks vs. Cardinals prediction & best bet
Stay ahead with the rest of our early NFL predictions.
Seahawks +1.5 (-115) ⭐⭐⭐⭐
The Seahawks thrashed the New Orleans Saints on Sunday, scoring 38 points in the first half to put the game to bed early. That afforded head coach Mike Macdonald the luxury of resting some of his key players with the short week ahead.
After losing a 16-15 dogfight to the San Francisco 49ers, the Cardinals were not so lucky. Running back James Conner will undergo ankle surgery after suffering a severe injury, compounding the lingering personnel concerns in Arizona's depleted cornerback room.
The Seahawks also have their fair share of injuries as cornerback Devon Witherspoon, safety Julian Love, safety Nick Emmanwori and running back Zach Charbonnet didn't play against the Saints.
While we don't know the status of the walking wounded for TNF, I'll take the Seahawks even if the status quo remains.
Seattle had the fifth-best offense via PFF entering Sunday's onslaught of New Orleans, and it hammered the Saints despite the aforementioned absentees. The same cannot be said for the Cardinals back in Week 1, who just about outlasted the Saints in New Orleans, 20-13.
The Cardinals, who had the 16th-ranked offense via PFF before playing the 49ers, struggled mightily in San Francisco. They mustered 265 yards of total offense and didn't score a touchdown until midway through the fourth quarter.
Due to playing two of the league's worst offenses (Carolina and New Orleans), their eighth-best defensive ranking is inflated. I'd suggest jumping on the +1.5 as soon as possible, as I don't think it will last.
Of the best sports betting sites, DraftKings' -110 represents the best value. Caesars and bet365 have already moved to +1, and FanDuel (-1.5) is juiced to -122. A winning $10 bet at DraftKings will yield a $9.09 profit.
Seahawks vs. Cardinals odds: Week 4
NFL odds update live in real time.
Seahawks vs. Cardinals opening odds
- Moneyline: Seahawks +115 | Cardinals -135
- Spread: Seahawks +2.5 (-110) | Cardinals -2.5 (-110)
- Over/Under: Over 46.5 (-110) | Under 46.5 (-110)
Seahawks vs. Cardinals odds analysis
I suggest jumping on the Seahawks at +1.5 as soon as possible, as I don't think it will last long. The Cardinals have already moved from -2.5 to -1.5, and I foresee this number shrinking further as the week transpires. Only 40% of bets back the Seahawks at the time of writing, but I also expect that percentage to increase.
Seahawks vs. Cardinals injury report
Seahawks vs. Cardinals game info
- When: Thursday, Sept. 25
- Kickoff: 8:15 p.m. ET
- Where: State Farm Stadium (Glendale, Ariz.)
- How to watch: Prime Video
Seahawks vs. Cardinals FAQs
Who is favored to win Seahawks vs. Cardinals?
The Cardinals are the marginal betting favorite, with their moneyline odds ranging from -116 to -120.
What are the opening odds for Seahawks vs. Cardinals?
The opening odds were as follows: Seahawks +2.5 (-110), Cardinals -2.5 (-110)
How do NFL odds work?
When betting on NFL odds, the point spread shows how many points the favorite needs to win by in order to cash the bet. For example, a favorite of -3 must win by more than 3 points to cover the spread, while an underdog at +3 must win outright or lose by fewer than 3 points to cover the spread.
Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total will be higher or lower than the set number.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
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