Eagles vs. Chiefs Parlay Picks & Predictions: NFL Week 2 SGP Odds

My Eagles vs. Chiefs parlay picks for today's Super Bowl rematch target Isiah Pacheco and DeVonta Smith player props, and the Eagles' moneyline.
Eagles vs. Chiefs Parlay Picks: SGP Odds & Predictions for NFL Week 2
Pictured: Philadelphia Eagles wide receiver DeVonta Smith (6) makes a catch for a touchdown against Kansas City Chiefs cornerback Jaylen Watson (35). Photo by Geoff Burke-Imagn Images.

My Eagles vs. Chiefs parlay picks and predictions call into question whether the Kansas City offense can stay afloat given the attrition to its wide receiver room.

As part of my NFL picks and predictions for Week 2, I have the Eagles going into Arrowhead Stadium and handling Kansas City. For our SGP, we’re highlighting skepticism over Isiah Pacheco’s workload and leaning into DeVonta Smith’s ability to break this game in Philly's favor.

The action kicks off at 4:25 p.m. ET from GEHA Field at Arrowhead Stadium in Kansas City, Mo. Philadelphia is a 1.5-point betting favorite. Our Gary Pearson offers his Eagles vs. Chiefs prediction for the affair.


🏈 Best Eagles vs. Chiefs parlay picks & predictions

NFL parlay picks odds subject to change.

  • Eagles ML (-122) ⭐⭐⭐⭐
  • Isiah Pacheco Under 36.5 rushing yards (-113) ⭐⭐⭐⭐
  • DeVonta Smith 70+ receiving yards (+105) ⭐⭐⭐⭐

Best parlay odds: +485 via DraftKings ($10 to win $48.50) 


💰 Best Eagles vs. Chiefs SGP bets

Here are my favorite Eagles vs. Chiefs parlay picks for this afternoon based on the best NFL odds for the full parlay.

🚀 Eagles ML (-122) ⭐⭐⭐⭐

The Chiefs are in trouble. With wide receiver Xavier Worthy knocked out of their Week 1 game early, Kansas City resorted back to being a dink-and-dunk offense. Worthy will remain out today.

Although the Eagles didn’t look great in an opening win over the Dallas Cowboys, I don’t know whether the Chiefs have the horses on the outside to take advantage of Philly’s potential weakness in the secondary. Though tight end Dallas Goedert’s absence could loom large, the Eagles still have ample weaponry on offense.

To avoid heartbreak with a -1.5 spread, we’ll settle for the moneyline with reasonable odds between -116 and -122 across various sportsbooks.

🚀 Isiah Pacheco Under 36.5 rushing yards (-113) ⭐⭐⭐⭐

I was surprised during the offseason when the Chiefs didn’t meaningfully upgrade their running back room, and I assumed it meant that Kansas City was ready to unleash Isiah Pacheco in 2025.

Well, he garnered just five carries for 25 yards in the opening loss to the Los Angeles Chargers. Though I expect the workload to tick up in this game, this still looks like a committee with Kareem Hunt, who drew equal carries to Pacheco in Week 1.

The Eagles held Javonte Williams to 3.6 yards per carry last week, and I don’t see Pacheco getting more than the 10 carries that it would take to clear his yardage prop at a similar YPC pace.

🚀 DeVonta Smith 70+ receiving yards (+105) ⭐⭐⭐⭐

The Chiefs have largely bottled up leading Eagles receiver A.J. Brown, giving up just 43 yards in the Super Bowl and allowing him to compile just 8 receiving yards in a 2023 regular-season matchup. Smith got free a few times in the Super Bowl, racking up 69 yards and a touchdown.

I see Smith as a beneficiary of Goedert’s absence in this game. QB Jalen Hurts should find him frequently to counter Kansas City’s anticipated heavy attention toward Brown on the other side.

Since a similar parlay at FanDuel had a less favorable line on Pacheco’s rushing while only offering +461 odds, we’re playing our SGP at DraftKings.

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💰 Best Eagles vs. Chiefs SGP odds

Our parlay calculator shows the best odds for every market across legal sportsbooks in your area.


Eagles vs. Chiefs expert picks


📺 Eagles vs. Chiefs game info

  • When: Sunday, Sept. 14
  • Kickoff: 4:25 p.m. ET
  • Where: GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
  • How to watch: FOX

❓NFL parlay betting FAQs

What are the best Eagles vs. Chiefs parlay picks?

The best Eagles vs. Chiefs parlay picks for today's game at 4:25 p.m. ET are Eagles moneyline, Isiah Pacheco Under 36.5 rushing yards, and DeVonta Smith 70+ receiving yards.

What is a parlay bet in the NFL?

A parlay combines multiple bets (spreads, totals, props, or moneylines) into one wager, with all selections needing to win for the bet to cash. Parlays are popular in the NFL betting because they offer bigger payouts.

How do NFL parlay odds work?

Parlay odds are calculated by multiplying the odds of each individual selection, which increases both the potential payout and the risk. The more legs you add, the higher the reward but the lower the probability of winning.

Are parlays a smart betting strategy for the NFL?

Parlays can be fun for chasing large payouts but are harder to win consistently. Many sharp bettors prefer single-game wagers, but NFL parlay bets can add excitement when used responsibly.

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