Eagles vs. Chiefs Anytime Touchdown Scorer Predictions Today: NFL Week 2

Last Updated: September 14, 2025 11:42 AM EDT β’ 5 minute read X Social Google News Link

The NFL's best game of Week 2 kicks off today at 4:25 p.m. ET at Arrowhead Stadium, and my Eagles vs. Chiefs anytime touchdown scorer predictions target three NFL picks with odds of +200 or longer to find the end zone.
Our Gary Pearson is backing the Eagles to cover the narrow 1-point spread in what he anticipates as a low-scoring game for his Eagles vs. Chiefs prediction. But with an Over/Under of 47 this afternoon, there will still be multiple touchdown scorers in this marquee showcase.
π° Eagles vs. Chiefs anytime touchdown scorer predictions
NFL touchdown scorer odds subject to change.
- Isiah Pacheco (+200 via DraftKings) βββββ
- DeVonta Smith (+215 via Caesars) ββββ
- Patrick Mahomes (++450 via DraftKings) βββ
π Best Eagles vs. Chiefs anytime touchdown scorer bets
Here are my favorite Eagles vs. Chiefs touchdown scorer picks based on the best NFL odds for this afternoon's matchup:
Isiah Pacheco, RB, Chiefs (+200) βββββ
Pacheco had a forgettable season debut in Brazil, totaling just 28 yards from scrimmage on seven touches. However, it was nice to see him get work in both the running and passing games and to get nearly equal yardage on the ground before and after contact.
The Eagles gave up 107 yards and two touchdowns to Dallas Cowboys running backs last week, and Pacheco is easily a tier above the likes of Javonte Williams and Miles Sanders.
Be sure to grab the +200 odds at DraftKings over the lower +155 odds from bet365, for an extra $4.50 in profit on a winning $10 bet.
DeVonta Smith, WR, Eagles (+215) ββββ

The Chiefs allowed five receptions on seven targets for 79 yards and two touchdowns to Los Angeles Chargers' No. 2 receiver Quentin Johnston last week. That immediately has me eyeing Smith to produce this afternoon after he caught all three of his targets for a mere 16 total yards last week.
Smith also caught four of five targets for 69 yards and a touchdown in the Super Bowl, and he'll be wanting to relive that performance at Arrowhead Stadium today.
Patrick Mahomes, QB, Chiefs (+450) βββ

Mahomes rushed for his first touchdown of the season last week and is already halfway to his regular-season total from the past two seasons.
The Eagles held Dallas Cowboys QB Dak Prescott to just one rushing attempt for three yards in the season-opener, but we've regularly seen Mahomes shoulder the extra burden when the Chiefs' offense struggles early in the season - and in their biggest matchups. He won't be shown up by Jalen Hurts' rushing abilities at home with Kansas City facing an 0-2 start.
π Eagles vs. Chiefs anytime TD scorer odds today
Our NFL player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
Eagles vs. Chiefs expert picks
- Eagles vs. Chiefs prediction
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- Eagles vs. Chiefs anytime touchdown scorer predictions
- Jalen Hurts vs. Patrick Mahomes player props
Anytime touchdown scorer predictions Week 2
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- Anytime touchdown scorer parlay picks
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- Falcons vs. Vikings anytime touchdown scorer predictions
πΊ Eagles vs. Chiefs game info
- When: Sunday, Sept. 14
- Kickoff: 4:25 p.m. ET
- Where: Arrowhead Stadium (Kansas City, Mo.)
- How to watch: FOX

β NFL betting FAQs
Who are the best anytime touchdown scorer predictions for Eagles vs. Chiefs today?
I'm backing Isiah Pacheco (+200), DeVonta Smith (+215), and Patrick Mahomes (+450) as my best anytime touchdown scorer predictions for this afternoon's 4:25 p.m. ET showdown.
What does anytime touchdown scorer mean?
An anytime touchdown scorer bet in NFL betting means you're wagering on a player to score a touchdown at any point during the game (excluding passing TDs). It's one of the most popular NFL prop bets.
What does anytime touchdown scorer mean for a QB?
An anytime touchdown scorer bet for a quarterback means the QB must run or catch a touchdown - passing touchdowns donβt count. It's a popular NFL prop bet for mobile or trick-play QBs.
Does a 2-point conversion count as a touchdown?
No, a 2-point conversion does not count as an anytime touchdown scorer. Only touchdowns scored in regulation or overtime count for this NFL prop bet.
How do NFL touchdown scorer bets work?
There are multiple different ways to make your NFL touchdown scorer predictions. You can wager on a player to score an anytime touchdown, which pays out if they reach the end zone at any point for a touchdown. You can also bet on a player to score the first or last touchdown, multiple touchdowns, or to score in a particular half or quarter for larger payouts.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
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