Best Cowboys vs. Eagles Anytime Touchdown Scorer Predictions Tonight: NFL Week 1

Touchdowns are back in style tonight when NFL Week 1 kicks off in Philadelphia at 8:20 p.m. ET (NBC), and my Cowboys vs. Eagles touchdown scorer predictions is backing a few key stars to reach the end zone.

My NFL picks focus on George Pickens to score in his Cowboys debut, and I'm also backing Saquon Barkley and A.J. Brown in my anytime touchdown scorer best bets as part of our NFL predictions for Week 1.

Want more insight on this matchup? Check out our full Cowboys vs. Eagles prediction for all of our best bets.

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🏈 Cowboys vs. Eagles touchdown scorer predictions

NFL touchdown scorer picks made Wednesday; odds subject to change.

• George Pickens to score anytime TD (+220 via FanDuel) ⭐⭐⭐
• Saquon Barkley to score anytime TD (-195 via DraftKings) ⭐
• A.J. Brown to score anytime TD (+160 via DraftKings) ⭐⭐⭐⭐

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💰 Best Cowboys vs. Eagles touchdown scorer bets

Here are my favorite Cowboys vs. Eagles touchdown scorer picks based on the best NFL odds for Week 1.

🔥 George Pickens anytime touchdown scorer (+220) ⭐⭐⭐

The Cowboys retooled their receiving room by adding George Pickens to be the second option to CeeDee Lamb. After Lamb led the NFL in red-zone targets in 2023 with 31, he ranked just 22nd last year with 16, of which only nine were caught and just three went for touchdowns.

Meanwhile, Jalen Tolbert notched 13 targets and caught eight for seven touchdowns. Pickens’ 6-foot-3 frame makes him a better boundary option than Lamb, whose 46.2% slot snap rate likely means lots of matchups with Philadelphia’s star nickel cornerback, Cooper DeJean.

There’s an argument that Pickens’ presence opens up Lamb for similar production as to what we saw in 2023, but I prefer just betting on Pickens for +220 to score a $22 profit on a $10 wager.

If you aren’t playing at FanDuel yet, make sure to check out our FanDuel promo code. In addition to bonus bets just for signing up, if you use your Thursday Touchdown Jackpot token, you’ll win a share of another $2 million in bonus bets if your player scores the first or last touchdown.

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🔥 Saquon Barkley anytime touchdown (-195) ⭐

Barkley led the Eagles in red-zone carries with 55 to Jalen Hurts’ 49 last season, and the latter even tallied 13 carries inside the five. The tush push simply wasn’t as effective without Jason Kelce. Hurts scored 13 times on 16 carries inside the five in 2023, but only managed 11 scores on 18 carries the following season.

The Cowboys swapped pass rusher Micah Parsons for interior defensive lineman Kenny Clark this offseason, which Jerry Jones hopes will help them up the middle. It won’t help them with outside runs, which is a strength of Barkley’s game.

Further, Jones’ confidence in Clark may be misplaced because the veteran defensive tackle ranked 83rd of 219 interior defensive linemen in run defense grade, per PFF. Trust Barkley to find paydirt on the first drive, last drive, stack your bonus bets, or take a risk and trust the below option to do so for Philadelphia.

Gary Pearson's NFL live betting guide suggests the best time to bet a Barkley touchdown will be before the game, so jump on this prediction ASAP!

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🔥 A.J. Brown anytime touchdown scorer (+160) ⭐⭐⭐⭐

Like Lamb, Brown’s red-zone volume has fallen off year-over-year. He recorded 15 red-zone targets and caught seven for four scores in 2023. The following season, he notched nine and caught six for three scores. Barkley (9) and DeVonta Smith (11) both racked up more targets.

Brown’s absence from four games may explain some of that downtick, as do the nagging injuries. But he enters the 2025 campaign healthy, and he remains the best boundary and jump-ball weapon in Hurts’ arsenal. Further, with Dallas opting to prioritize its run defense over the pass rush, Hurts should have more time to throw, potentially creating more opportunities for him to connect with Brown on a deep ball. 

The Cowboys may have ball hawks at cornerback, but they don’t have good coverage guys on the boundary. Trevon Diggs ranked 121st of 222 corners in pass coverage last year with a 60.3 coverage grade. On the other side of the field will be Kaiir Elam, a former first-round pick who couldn’t get on the field with the Bills. His career coverage grade of 66.4 is bad, and his forced incompletion rate of 5% is even worse.

I knew I wanted some action on A.J. Brown this week, but when I opened up our NFL player prop odds tool and saw him sitting at +160 on DraftKings, I got excited.

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📈 Cowboys vs. Eagles anytime TD scorer odds

Our NFL player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

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💡 Cowboys vs. Eagles expert picks

• Cowboys vs. Eagles prediction
• Best Cowboys vs. Eagles player prop bets
• Cowboys vs. Eagles parlay picks
• Best Cowboys vs. Eagles anytime touchdown scorer predictions
• Cowboys vs. Eagles first touchdown scorer predictions
• Cowboys vs. Eagles weather report
• Cowboys vs. Eagles live betting strategy
• Cowboys vs. Eagles expert picks tonight

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📺 Cowboys vs. Eagles game info

• When: Thursday, Sept. 4
• Kickoff: 8:20 p.m. ET
• Where: Lincoln Financial Field (Philadelphia)
• How to watch: NBC

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❓NFL betting FAQs

What does anytime touchdown scorer mean?

An anytime touchdown scorer bet in NFL betting means you're wagering on a player to score a touchdown at any point during the game (excluding passing TDs). It's one of the most popular NFL prop bets.

What does anytime touchdown scorer mean for a QB?

An anytime touchdown scorer bet for a quarterback means the QB must run or catch a touchdown - passing touchdowns don’t count. It's a popular NFL prop bet for mobile or trick-play QBs.

Does a 2-point conversion count as a touchdown?

No, a 2-point conversion does not count as an anytime touchdown scorer. Only touchdowns scored in regulation or overtime count for this NFL prop bet.

How do NFL touchdown scorer bets work?

There are multiple different ways to make your NFL touchdown scorer predictions. You can wager on a player to score an anytime touchdown, which pays out if they reach the end zone at any point for a touchdown. You can also bet on a player to score the first or last touchdown, multiple touchdowns, or to score in a particular half or quarter for larger payouts.

You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.

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