Cowboys vs. Eagles Tonight: Live Betting & Prop Strategy

Get ready for Cowboys vs. Eagles tonight with our live betting & prop strategy for the NFL's 2025 season opener.

Esten McLaren

Last Updated: September 4, 2025 4:39 PM EDT • 2 minute read

Cowboys vs. Eagles Tonight: Live Betting & Prop Strategy — Pictured: Philadelphia Eagles wide receiver DeVonta Smith (6) celebrates with running back Saquon Barkley (26) after scoring a touchdown. Photo by Geoff Burke-Imagn Images.

The reigning Super Bowl champion Philadelphia Eagles open the 2025 NFL season at home against the Dallas Cowboys with tonight's kickoff set for 8:20 p.m. ET at Lincoln Financial Field.

The Eagles are as much as 8.5-point betting favorites by the latest NFL odds, and that large spread could open the door for some intriguing in-game betting opportunities, according to our Gary Pearon's NFL live betting guide for Week 1.

Cowboys vs. Eagles live betting playbook & key insights

Pearson expects Philly to control the game, as he said in his Cowboys vs. Eagles prediction. Back CeeDee Lamb Over receiving yards if Dallas falls behind early, and lean Saquon Barkley Overs on carries/yards as Philly seeks clock control. Target late-stage Hurts TDs with your NFL picks.

Game details & live betting strategy

Matchup snapshot

Event: Cowboys vs. Eagles
Date & time: Tonight, Thursday, Sept 4, 8:20 p.m. ET
Venue: Lincoln Financial Field, Philadelphia
Coverage: NBC

Live betting game plan

If Dallas trails early

Bet Lamb Over receiving yards - Expect Dallas to abandon the run; soft-zone coverage might open up routes for Lamb
Back Barkley Overs (carries & yards) - Eagles can control tempo by attacking one of the league’s weakest run defenses

Timing for prop plays

Hurts TDs: 10 of his 14 rushing touchdowns came in the 3rd and 4th quarters (our Matt Jacob backs a Hurts TD with his best Cowboys vs. Eagles player prop bets)
Prescott passing TDs: 10 of his 11 came when the Cowboys were trailing
Barkley TD timing: 6 of his 15 touchdowns came in the 4th quarter

Scoring tempo trends

Eagles: best scoring in 4th quarter, weakest in 1st
Cowboys: strongest in 2nd quarter

Weather watch

Always check SBR’s weather report - rain favors run-heavy strategies and lower variance plays. Don't miss our Cowboys vs. Eagles weather report for more.

Cowboys vs. Eagles expert picks

Cowboys vs. Eagles prediction
Best Cowboys vs. Eagles player prop bets
Cowboys vs. Eagles parlay picks
Best Cowboys vs. Eagles anytime touchdown scorer predictions
Cowboys vs. Eagles first touchdown scorer predictions
Cowboys vs. Eagles weather report
Cowboys vs. Eagles live betting strategy
Cowboys vs. Eagles expert picks tonight

Cowboys vs. Eagles FAQs

What prop plays are best if the Cowboys trail early?

CeeDee Lamb Over receiving yards, Saquon Barkley Overs on carries/yards.

When are Eagles and Cowboys most likely to score?

Eagles in the 4th quarter, Cowboys in the 2nd.

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Written by:
Esten McLaren

Esten is the Content Manager for SportsbookReview.com. He has been in the sports betting industry since the legalization of mobile sports betting in New Jersey, and with SportsbookReview prior to the launch of sports betting in Ontario. Esten's previous stops include the USA TODAY network, including GolfWeek. He previously worked in the fantasy sports industry, with FNTSY Sports Network, theScore, and USA TODAY, where he started to build his NFL experience in the iGaming industry. Esten graduated from the College of Sports Media with a diploma in Radio and Television Sports Broadcasting after acquiring a degree in Biological Sciences from the University of Guelph. He has appeared on FNTSY Sports Network, VSiN, and VSiN's Long Shots podcast, where he correctly called Will Zalatoris as the winner of the 2022 FedEx St. Jude Championship. Esten is a big proponent of the entertainment side of sports betting and loves to dip his toes into the novelty and alt-markets while chasing long shots with reduced wagers on golf outrights and futures markets. He's also been known to sprinkle some lunch money on touchdown-scorer parlays with two notable hits funding his bankroll. Esten looks at sports betting much like golf and advises beginner bettors to compete against themselves rather than being concerned with what others may or may not be doing based on social media claims.