Commanders vs. Chiefs Prediction & Latest Odds Week 8: Monday Night Football Betting Preview
Last Updated: October 22, 2025 1:12 PM EDT โข 2 minute read X Social Google News Link
Washington Commanders QB Jayden Daniels is reportedly out this week, as I make my best Commanders vs. Chiefs prediction based on opening odds for Monday Night Football.
Given that crucial injury update, this spread is bound to grow as I make my early NFL picks as part of our NFL predictions for Week 8, with Kansas City currently a 10-point betting favorite. Monday Night Football kicks off from GEHA Field at Arrowhead Stadium in Kansas City, Mo., at 8:15 p.m. ET (ABC/ESPN).
๐ Commanders vs. Chiefs prediction & betting preview
Stay ahead with the rest of our early NFL predictions for Week 8.
๐ด Chiefs -9.5 (-110) โญโญโญโญ
The Commanders were pulverized by the Cowboys, even with Daniels on the field, and theyโve now lost three of their last four.
Meanwhile, the Chiefs have won four of their last five, scoring at least 28 points in four consecutive games. The Commanders are allowing 24.3 points and 238.3 passing yards per game. The Chiefs have the seventh-ranked passing offense, and Patrick Mahomes has thrown for at least 250 yards in four straight games. All this has the Chiefs as one of the safest NFL survivor picks for Week 8.
Most of the best sports betting sites have already moved off the 9.5, but that number remains at FanDuel. The price of -110 implies a 52.38% chance the Chiefs cover. A $10 bet would profit $9.09.
It looks like sportsbooks aren't expecting Daniels to be out there, but 10 points would still be my limit if he doesn't go. Our Gary Pearson backs the Chiefs as one of his strongest NFL picks against the spread this week.
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๐ฎ NFL expert picks
Here are our other NFL predictions for this week's prime-time games:
- Vikings vs. Chargers prediction
- Packers vs. Steelers prediction
- Commanders vs. Chiefs prediction
๐ Commanders vs. Chiefs odds
Latest NFL odds updated live in real time.
๐ Commanders vs. Chiefs opening odds
- Moneyline: Commanders +150 | Chiefs -200
- Spread: Commanders +6 (-110) | Chiefs -6 (-110)
- Over/Under: Over 51 (-110) | Under 51 (-110)
💡 Commanders vs. Chiefs odds analysis
This spread quickly hit double digits at the best sports betting apps. All four of the Chiefs' wins are by at least 13 points, so it will be interesting to see where this settles.
The total ranges from 47.5 to 51, but will likely trend down with Daniels ruled out.
Our NFL AI predictions this week have the Chiefs winning comfortably.
๐บ How to watch Commanders vs. Chiefs
- Matchup: Commanders vs. Chiefs
- When: Monday, Oct. 27
- Kickoff: 8:15 p.m. ET
- Where: GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
- TV: ABC/ESPN
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Philip Wood X social