Commanders vs. Chiefs Odds & Predictions: Our Expert Picks for Monday Night Football
Last Updated: October 27, 2025 5:15 PM EDT • 3 minute read X Social Google News Link
Patrick Mahomes and the Kansas City Chiefs look to stay hot tonight against the short-handed Washington Commanders on Monday Night Football (8:15 p.m. ET, ABC/ESPN), and our Chiefs vs. Commanders expert picks are siding with the home favorites for this MNF clash from GEHA Field at Arrowhead Stadium in Kansas City to close NFL Week 8.
📊 Commanders vs. Chiefs odds: Monday Night Football
🏈 Commanders vs. Chiefs expert picks
See all of our NFL picks for every game based on the latest NFL odds.
| Wager type | Best bet | Best odds |
|---|---|---|
| Game prediction | Chiefs -11.5 | -108 via DraftKings |
| Over/Under pick | Over 47.5 | -115 via FanDuel |
| Best player prop bet | Marcus Mariota Under 200.5 passing yards | -113 via DraftKings |
| Best anytime TD pick | Terry McLaurin anytime TD | +300 via FanDuel |
| Best first TD pick | Isiah Pacheco first TD | +1100 via bet365 |
| Best Patrick Mahomes prop bet | Patrick Mahomes Over 2.5 passing TDs | +127 via DraftKings |
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🔮 Commanders vs. Chiefs prediction
After a slow start, the Chiefs have ripped off four wins in their last five games following a 31-0 blowout win over the Las Vegas Raiders last week. And our NFL experts are expecting the good times to keep rolling for Mahomes and Co. tonight at home.
Our NFL expert Gary Pearson is laying the points with confidence on the Monday Night Football favorites in his Commanders vs. Chiefs prediction, as he focuses on a major mismatch between Kansas City's explosive offense and Washington's leaky secondary. His MNF preview also features the latest betting trends, injury report, weather, and more.
💵 Monday Night Football predictions
- Chiefs -11.5 (-108 via DraftKings) ⭐⭐⭐⭐
- Over 47.5 (-115 via FanDuel) ⭐⭐⭐
🔥 Commanders vs. Chiefs player props
Kansas City's dynasty has revolved around the brilliant connection between Mahomes and tight end Travis Kelce, but our NFL expert Phil Wood expects a quiet day from the star pass-catcher with Mahomes targeting his downfield threats tonight.
His favorite bet, though, revolves around fill-in quarterback Marcus Mariota and his potential struggles against a dominant Chiefs pass defense. He breaks down all of his picks in greater detail in his Commanders vs. Chiefs player props, while NFL expert Liam Fox focuses more specifically on the Chiefs QB in his Patrick Mahomes player prop bets.
💵 Monday Night Football player props
- Marcus Mariota Under 200.5 passing yards (-113 via DraftKings) ⭐⭐⭐⭐
- Patrick Mahomes Over 39.5 yards longest completion (-110 via BetMGM) ⭐⭐⭐⭐
- Travis Kelce Under 3.5 receptions (+106 via DraftKings) ⭐⭐⭐
💪 Commanders vs. Chiefs anytime TD pick
We have been white hot on our anytime TD picks this season, and our NFL expert Esten McLaren is taking his shot on two talented receivers and an overlooked tight end with his best touchdown bets tonight for Monday Night Football.
Here's a look at the three players McLaren is targeting to score tonight, which he breaks down even further in his Commanders vs. Chiefs anytime TD picks.
💵 Monday Night Football anytime TD picks
- Xavier Worthy to score anytime TD (+160 via FanDuel) ⭐⭐⭐⭐
- Terry McLaurin to score anytime TD (+300 via FanDuel) ⭐⭐⭐⭐⭐
- Noah Gray to score anytime TD (+400 via DraftKings) ⭐⭐⭐
🥇 Commanders vs. Chiefs first TD pick
After cashing yet another first touchdown pick last night with Tucker Kraft rumbling into the end zone, our NFL expert Sean Tomlinson has his sights set on another big payday tonight as he targets a few relatively unheralded players to reach pay dirt.
Tomlinson is targeting both starting running backs tonight at long odds to open the scoring on Monday Night Football, and he's taking a shot on a dart throw at 35/1 with the juiciest of his Commanders vs. Chiefs first TD picks.
💵 Monday Night Football first TD picks
- Isiah Pacheco to score first TD (+1100 via bet365) ⭐⭐⭐⭐
- Jacory Croskey-Merritt to score first TD (+1400 via bet365) ⭐⭐⭐
- Noah Gray to score first TD (+3500 via FanDuel) ⭐⭐⭐
🚀 Commanders vs. Chiefs same-game parlay
It wouldn't be an NFL prime-time matchup without our best SGP bet for the night, and we're back for another potential payday with our best Commanders vs. Chiefs same-game parlay for Monday Night Football.
Our NFL expert Brenden Schaeffer is back in action with a three-leg SGP parlay at +425 odds via DraftKings focused on a big Chiefs win behind a dominant defensive effort and an underrated rusher playing a key role in the passing game.
💵 Monday Night Football same-game parlay (SGP)
- Chiefs -10.5 (-115) ⭐⭐⭐⭐
- Jacory Croskey-Merritt Under 48.5 rushing yards (-111) ⭐⭐⭐⭐
- Brashard Smith Over 17.5 receiving yards (-114) ⭐⭐⭐⭐⭐
Best odds: +425 via DraftKings ($10 to win $42.50)
📺 How to watch Monday Night Football: Commanders vs. Chiefs
- Date: Monday, Oct. 27
- Kickoff: 8:15 p.m. ET
- Where: GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
- TV: ABC/ESPN
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