Best Chiefs vs. Chargers Player Prop Bets: NFL Week 1 Odds & Expert Picks

My best Chiefs vs. Chargers player props are the Under on Patrick Mahomes' passing yardage, the Over on Omarion Hampton's receiving yardage, and the Under on Keenan Allen's receptions prop.
Best Chiefs vs. Chargers Player Prop Bets: NFL Week 1 Odds & Expert Picks
Pictured: Los Angeles Chargers quarterback Justin Herbert (10) talks with wide receiver Keenan Allen (13). Photo by Kirby Lee via Imagn Images.

The NFL is off to Brazil, and we’re here to discuss the best Chiefs vs. Chargers player props for Friday night’s action. You won’t want to miss out on these NFL picks, including targeting the Under on Patrick Mahomes' passing yardage prop.

Kickoff is scheduled for 8 p.m. ET (streaming on YouTube) from Corinthians Stadium in Sao Paulo, Brazil. The Chiefs are listed as a 3-point betting favorite, and you can check out our entire NFL predictions for Week 1 for more action on this game and others!

That includes Mike Spector's Chiefs vs. Chargers prediction for tonight's matchup.


🏈 Best Chiefs vs. Chargers player props: Week 1

NFL player prop bets made Friday; odds subject to change.

  • Patrick Mahomes Under 246.5 passing yards (-112 via DraftKings) ⭐⭐⭐⭐
  • Omarion Hampton Over 12.5 receiving yards (-113 via FanDuel) ⭐⭐⭐⭐
  • Keenan Allen Under 3.5 receptions (+114 via FanDuel) ⭐⭐⭐
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💰 Best Chiefs vs. Chargers player prop bets

Our NFL player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

⬇️ Patrick Mahomes Under 246.5 passing yards (-112) ⭐⭐⭐⭐

Best Chiefs vs. Chargers Player Prop Bets: NFL Week 1 Odds & Expert Picks
Pictured: Kansas City Chiefs quarterback Patrick Mahomes (15) drops back to pass. Photo by Denny Medley via Imagn Images.

The world loves Patrick Mahomes, but let’s not forget that he averaged only 245.5 passing yards per game last year, a career-low mark for him as a starter. Some of that underperformance has to do with the injury to Rashee Rice, who will also miss Friday’s game, this time due to a suspension. Mahomes’ top three receivers without Rice are Xavier Worthy, Hollywood Brown, and JuJu Smith-Schuster. Gross.

On the other side of the field is an intimidating Chargers defense paired with a complementary slow-paced offense. The Chargers’ offense ranked 10th in rushing-play percentage last year, with the most seconds per play. Meanwhile, L.A. ranked an impressive seventh in total passing yards allowed per game (209.9) and held Mahomes under this number twice.

You’ll find Mahomes’ passing yardage prop sitting at a lofty 246.5 at DraftKings, and you can buy the under for the nice price of -112 (52.8% implied probability). That means a $10 bet will offer a nice $8.93 profit. Make sure to add this Chiefs vs. Chargers player prop to your card before kickoff!

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⬆️ Omarion Hampton Over 12.5 receiving yards (-113) ⭐⭐⭐⭐

Best Chiefs vs. Chargers Player Prop Bets: NFL Week 1 Odds & Expert Picks
Pictured: Los Angeles Chargers running back Omarion Hampton (8) carries the ball. Photo by Kirby Lee via Imagn Images.

I was somewhat surprised when I opened up our NFL player prop odds tool to see where the market had landed on Omarion Hampton. Despite being named the starting running back for Friday’s game, Hampton’s receiving yardage prop was sitting at a lowly 12.5! Hampton earned the second-best receiver rating among this year’s crop of rookie running backs and averaged 3.2 receptions and 31.1 receiving yards per game in his final year of college football.

While the Chargers may rotate in Najee Harris, Hampton has the better receiving chops. Harris totaled 36 receptions last year, but Hampton caught more passes in five fewer games at the college level. Hampton also has higher upside athletically, with him taking his catches for nearly 10 yards per reception versus Harris taking his for 7.9 (a career-best, mind you – he averages just 6.4 yards per reception since entering the NFL). 

With the Chiefs favored, the Chargers may need to rely more on the passing game than offensive coordinator Greg Roman may like, and I love Hampton to go over 12.5 receiving yards for -113 (53%) at FanDuel. A $10 wager will earn you a tidy $8.85 profit. You can even ladder this up to 20 yards (+176 at FanDuel) or 25 yards (+223 at DraftKings).

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⬇️ Keenan Allen Under 3.5 receptions (+114) ⭐⭐⭐

Best Chiefs vs. Chargers Player Prop Bets: NFL Week 1 Odds & Expert Picks
Pictured: Los Angeles Chargers wide receiver Keenan Allen (13) runs the ball. Photo by Gary A. Vasquez via Imagn Images.

The Chargers added Ladd McConkey to pick up the slack left behind by Keenan Allen, so when they reunited with the veteran receiver, I didn’t understand how they would find a way to get them both on the field. McConkey spent 64.6% of his snaps in the slot last year, while Allen spent 43.2% of his snaps there last season and 55.5% of them in his previous year with L.A. (2023).

It’s not like Los Angeles has the receiver talent to run four- or five-receiver sets, so if Roman wants to use both McConkey and Allen, one will likely have to be on the boundary. That doesn’t favor either of their skill sets. It’s far likelier that these guys spend a healthy chunk of the game rotating, and with McConkey offering more upside at this point in his career, he probably gets the nod before Allen.

Allen simply may not see the volume fans and bettors are used to seeing from him. Bet him to stay Under 3.5 receptions for +114 (46.7%) at FanDuel. A $10 bet will earn you a nice $11.40 profit.

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📺 Chiefs vs. Chargers game info

  • When: Friday, Sept. 5
  • Kickoff: 8 p.m. ET
  • Where: Corinthians Arena (Sao Paulo, Brazil)
  • How to watch: YouTube

💡 More Chiefs vs. Chargers expert picks


❓ Chiefs vs. Chargers FAQs

What are the best Chiefs vs. Chargers player props?

My best Chiefs vs. Chargers player props are Patrick Mahomes Under 246.5 passing yards for -112 at DraftKings and Omarion Hampton Over 12.5 receiving yards for -113 at FanDuel.

When is the Chiefs vs. Chargers game?

Friday’s Chiefs vs. Chargers game is scheduled for 8 p.m. ET (YouTube).

How do NFL player props work?

Player props are wagers on individual performances rather than the outcome of the game. Common props include passing yards, rushing yards, receiving yards, and touchdown scorers. For example, if a QB’s passing yards line is set at 250.5, you can bet the Over (251-plus yards) or Under (250 or fewer yards). You can also bet on if a specific player will score a touchdown in the entire game, the first or last touchdown, and more NFL odds markets.

You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.

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