Cardinals vs. Cowboys Prediction: Monday Night Football Picks & MNF Odds Tonight
        
    Last Updated: November 3, 2025 7:26 PM EST • 3 minute read X Social Google News Link
                                Monday Night Football between the Arizona Cardinals and Dallas Cowboys wraps up Week 9, and I break down the matchup with my Cardinals vs. Cowboys prediction tonight.
I anticipate a bounce-back performance from Dallas, which is a 3-point home favorite, as well as tight end Jake Ferguson. Our Week 9 NFL predictions conclude at 8:15 p.m. ET from AT&T Stadium in Arlington, Texas (ABC/ESPN).
✅ Cardinals vs. Cowboys prediction & expert picks
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Kyler Murray not starting is fortuitous news for the Cowboys, as the Cardinals' No. 1 quarterback is 9-0 at AT&T Stadium (including college and high school). While stand-in QB Jacoby Brissett has played well in Murray's absence, he doesn't offer the same dual-threat ability. That's exquisite news for a Dallas team with the second-worst defensive DVOA ranking.
The Cardinals are 0-1 on the road with Brissett under center and 1-2 overall, with their only win in Week 1 against a poor New Orleans Saints team.
The Cowboys, meanwhile, are undefeated at home (2-0-1) and are notably superior at AT&T Stadium, where they tied the Green Bay Packers, who are among the Super Bowl odds contenders.
I also feel the lopsided loss in Denver will help Dallas, particularly Dak Prescott, who endured his worst outing of the season. Prescott, who has the highest ranking in our Clutch Factor power rankings for QBs with a losing record, will be focused on having a bounce-back game. And our Cowboys vs. Cardinals player props are calling for just that.
Irrespective of Dallas' poor defense, I give the home team the edge due to its palpable advantage under center.
Of the best sports betting sites, BetMGM's -115 odds offer the best value. Those odds carry a 53.49% implied probability and will profit $8.70 on a winning $10 bet.
Score prediction: Cowboys 30, Cardinals 24
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🆚 Key matchup to watch on MNF
Jake Ferguson vs. Cardinals defense
While the Cardinals have the 12th-best defensive pass DVOA, Nick Rallis' unit allows the fourth-most yards to opposing tight ends, with an average of 68.71 per game. Ferguson hasn't hit the Over on this total in three games and was completely absent from the passing attack in Denver, with one target and no receptions.
However, with this favorable matchup, I expect him to get back to being an integral component of Prescott's aerial attack. In the Cardinals' last game, Green Bay's Tucker Kraft had 58 receiving yards on five receptions.
Ferguson hit the Over in two of three home games, averaging 49 yards. He also hit the Over in two of the Cowboys' three wins, and despite amassing only 29 receiving yards in the previous home game against Washington, he caught two TD passes.
bet365 and BetMGM are the only two of the best sports betting apps offering the lower total of 39.5 yards. BetMGM offers the slightly better value (-110), where a winning $10 bet will profit $9.09.
Best prop bet: Jake Ferguson Over 39.5 receiving yards (-110 via BetMGM)
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📈 Cardinals vs. Cowboys betting trends
| Cardinals | Statistic | Cowboys | 
|---|---|---|
| 2-5 | W-L record | 3-4-1 | 
| 4-3 | ATS record | 4-4 | 
| 4-3 | O/U record | 6-2 | 
| 4.9 | Yards per play | 6.0 | 
| 5.2 | Yards allowed per play | 6.2 | 
| -1 | Turnover margin | -1 | 
| 0-5 | Last 5 games | 2-2-1 | 
| L, 27-23 vs. Packers | Previous result | L, 44-24 vs. Broncos | 
🚑 Cardinals vs. Cowboys injury report
🌤️ Cardinals vs. Cowboys weather
AT&T Stadium has a retractable roof, which will be closed if any inclement conditions arise.
Check our NFL weather report for the latest forecasts and betting impacts for every game this week.
📺 How to watch Monday Night Football: Cardinals vs. Cowboys
- Date: Monday, Nov. 3
 - Kickoff: 8:15 p.m. ET
 - Location: AT&T Stadium (Arlington, Texas)
 - TV: ESPN
 
💡 More MNF expert picks
- Cardinals vs. Cowboys prediction
 - Cardinals vs. Cowboys player props
 - Cardinals vs. Cowboys same-game parlay
 - Cardinals vs. Cowboys anytime touchdown scorer predictions
 - Cardinals vs. Cowboys first touchdown scorer predictions
 - Cardinals vs. Cowboys expert picks
 - Dak Prescott player prop bets
 
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        Gary Pearson X social