Cardinals vs. Seahawks Picks, Predictions NFL Week 6: NFC West Foes Jockey for Position
It’s been a tighter race than expected in the NFC West this season. Every win is important as the Arizona Cardinals head north to take on the Seattle Seahawks. Here are our top picks as the 2-3 Seahawks host the 2-3 Cardinals in Week 6.
Points have been hard to come by for the Cardinals, who took a step back from last year in nearly every offensive category. Matching their blazing 8-2 start from last season would always be a tall task, but 2-3 isn’t good enough for a team hoping to compete for a playoff spot.
Luckily, they still have time to rebound, as do the Seattle Seahawks. Every NFC West team has experienced some hardships, meaning the division title is still more-or-less wide open. The Seahawks are dealing with key injuries, including a season-ending one for running back Rashaad Penny. Can rookie RB Kenneth Walker III take his place?
Here are our top Cardinals-Seahawks Week 6 NFL picks (odds via Caesars Sportsbook, FanDuel Sportsbook and DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).
Cardinals vs. Seahawks Game Info
- Date: Sunday, Oct. 16, 4:05 p.m. ET
- TV: FOX
- Location: Lumen Field, Seattle, WA
- Weather: 79 degrees, 1% chance of precipitation, 6-mph winds
Cardinals vs. Seahawks Odds
Cardinals vs. Seahawks Odds Analysis
The Over/Under market for this matchup opened at 47 before significantly growing to its current total of 50.5 as of Friday afternoon. 58% of the tickets and 60% of the cash was wagered on the Over.
The Cardinals opened as 2.5-point favorites, but the spread has since fallen to 2. Most sportsbooks, however, still offer +/- 2.5 in this market.
Cardinals vs. Seahawks Picks
- Cardinals -2.5 (-105 via Caesars) ★★★★★
- Over 50.5 (-106 via FanDuel) ★★★★
- Marquise Brown anytime touchdown scorer (+115 via DraftKings) ★★★★★
Cardinals vs. Seahawks ATS Pick
Cardinals -2.5 (-105) ★★★★★
The schedule hasn't been friendly to the Cardinals so far, including games against the Kansas City Chiefs and Philadelphia Eagles. The Seahawks are the worst defensive team Arizona has played this season. It's an opportune spot for Cardinals quarterback Kyler Murray and his offense to play like they did at this time last year.
Seattle has given up an NFL-worst 2,150 scrimmage yards in five games to its opponents, including nine rushing touchdowns and another nine passing. The spread may be better value than betting the money line, as Seattle’s O-line has been capable this season and could keep things close.
Cardinals vs. Seahawks O/U Pick
Over 50.5 (-106) ★★★★
Many believe the Cards are better than the 21 points per game they’ve averaged, and this matchup is a great way to test that theory. Arizona may have defensive problems of its own, but the Cardinals' untapped offensive ability can shine against a Seahawks squad that’s given up 30.8 PPG – another league high.
The likelihood of the Seahawks helping to hit the Over also seems plausible. They scored 32 points against the New Orleans Saints last week – a team whose defense isn’t exactly a walk in the park. With veteran quarterback Geno Smith under center, and playing the best football of his journeyman career, their offense should continue to hum.
Cardinals vs. Seahawks Prop Pick
Brown anytime touchdown scorer (+115) ★★★★★
The Cardinals’ offense has been wide receiver Marquise Brown’s playground this season, with Murray targeting him a whopping 55 times through five games. The lion’s share may eventually be redirected towards star wideout DeAndre Hopkins , who's set to make his season debut in Week 7. This could be your last chance to absorb the value of this particular betting scenario.
Brown already has three receiving touchdowns, including one in each of his last two games. He should have no problem finding the end zone once again in Week 6, given how poor the Seahawks are at stopping anything through the air.
Where to Bet on Cardinals vs. Seahawks Picks
Cardinals-Seahawks picks made 10/14/2022 at 2:56 p.m. ET
