Buccaneers vs. Panthers Player Props: Best Bets & TD Picks for NFL Week 16
Last Updated: December 21, 2025 5:45 AM EST • 3 minute read X Social Google News Link
My best Buccaneers vs. Panthers player props for Sunday’s 1 p.m. ET (FOX) game at Bank of America Stadium in Charlotte, N.C., focus on Tetairoa McMillan, Baker Mayfield, and Sean Tucker. The Buccaneers are favored by 3.
Below, I highlight specific matchups to look out for with the NFC South lead on the line this Sunday. For more coverage of this game and the rest of the weekend’s slate, check out our NFL Week 16 predictions.
🏈 Buccaneers vs. Panthers player prop bets
See the latest NFL odds and our experts' NFL picks for every game this season.
| Player | Prop bet | Best odds | Confidence |
|---|---|---|---|
| Tetairoa McMillan, WR, Panthers | Over 56.5 receiving yards | -114 via DraftKings | ⭐⭐⭐⭐ |
| Baker Mayfield, QB, Buccaneers | Over 0.5 interceptions | +104 via DraftKings | ⭐⭐⭐⭐ |
| Sean Tucker, RB, Buccaneers | Score a touchdown | +275 via bet365 | ⭐⭐⭐ |
💰 Buccaneers vs. Panthers best bet
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Tetairoa McMillan Over 56.5 receiving yards (-114) ⭐⭐⭐⭐
McMillan has caught two or fewer passes in three consecutive games, and he’s failed to top 43 yards in any of those contests. But he still has seven games with at least 60 yards this season.
The Buccaneers are allowing the third-most passing yards per game (246.9), and despite McMillan’s recent struggles, he still leads the Panthers in receptions (59), targets (102), and yards (851).
🔥 More Buccaneers vs. Panthers prop picks
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 16.
Baker Mayfield Over 0.5 interceptions (+104) ⭐⭐⭐⭐
Mayfield has only thrown seven interceptions this season, but five of those have come in his last five games. He’s thrown a pick in four of his last five, and the only time he didn’t, he was facing the Cardinals, who have just nine interceptions this season.
The Panthers have picked off 12 passes, which is tied for the seventh-most in the league, making this one of the most valuable Buccaneers vs. Panthers player props.
Sean Tucker to score a touchdown (+275) ⭐⭐⭐
With Rachaad White and Bucky Irving both healthy, the backfield is crowded in Tampa Bay. Still, Tucker, who only had four carries last week, continues to make his presence near the goal line felt. He’s scored in back-to-back weeks, and he leads the Buccaneers with six rushing touchdowns.
The Panthers have allowed 17 rushing touchdowns this season, the seventh-most in the league.
📺 How to watch Buccaneers vs. Panthers
- Date: Sunday, Dec. 21
- Kickoff: 1 p.m. ET
- Location: Bank of America Stadium (Charlotte, N.C.)
- TV: FOX
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