NFL AI Predictions Week 5: ATS Picks & Score Projections for Every Game
Our NFL AI predictions are 36-28 against the spread (56.3%) with a blistering 14-6 record on our best bets (70%) entering NFL Week 5 - including predicting the exact score for Thursday Night Football as one of our top NFL picks.
We've trained the latest model from ChatGPT to make its weekly NFL predictions and projected scores for every game this week based on real-time search and advanced metrics, while offering a full box score and game preview for its five most confident picks.
If you can beat the bot in our free weekly NFL contest, you'll enter a draw to win SBR swag while competing for more than $5,000 in total prizes.
🤖 NFL AI predictions for Week 5
NFL AI predictions and score projections via ChatGPT simulation model; ATS pick confidence based on a 1-to-5-star scale and latest NFL odds.
| Prediction | ATS pick | Confidence |
|---|---|---|
| Rams 27, 49ers 13 | Rams -8.5 | ⭐⭐⭐⭐⭐ |
| Vikings 26, Browns 23 | Browns +3.5 | ⭐⭐⭐ |
| Jets 23, Cowboys 21 | Jets +2.5 | ⭐⭐⭐ |
| Eagles 30, Broncos 16 | Eagles -3.5 | ⭐⭐⭐⭐⭐ |
| Texans 27, Ravens 24 | Texans -1.5 | ⭐⭐⭐ |
| Giants 20, Saints 19 | Giants +1.5 | ⭐⭐ |
| Colts 28, Raiders 20 | Colts -6.5 | ⭐⭐⭐⭐⭐ |
| Dolphins 31, Panthers 23 | Dolphins -1.5 | ⭐⭐⭐⭐ |
| Seahawks 23, Buccaneers 13 | Seahawks -3.5 | ⭐⭐⭐⭐⭐ |
| Cardinals 26, Titans 17 | Cardinals -7.5 | ⭐⭐⭐⭐ |
| Chargers 28, Commanders 24 | Chargers -2.5 | ⭐⭐⭐⭐ |
| Lions 30, Bengals 27 | Bengals +10.5 | ⭐⭐⭐ |
| Bills 30, Patriots 17 | Bills -8.5 | ⭐⭐⭐⭐⭐ |
| Chiefs 26, Jaguars 23 | Jaguars +3.5 | ⭐⭐⭐ |
🐏 Rams (-8.5) vs. 49ers
| Team | 1Q | 2Q | 3Q | 4Q | Final |
|---|---|---|---|---|---|
| 49ers | 0 | 6 | 0 | 7 | 13 |
| Rams | 7 | 10 | 3 | 7 | 27 |
🔢 Rams projected stats
- Passing leader: Matthew Stafford – 22/33, 268 yards, 2 TD, 1 INT
- Rushing leader: Kyren Williams – 18 rushes, 86 yards, 1 TD
- Receiving leader: Puka Nacua – 7 receptions, 92 yards, 1 TD
🔢 49ers projected stats
- Passing leader: Mac Jones – 19/31, 214 yards, 1 TD, 1 INT
- Rushing leader: Christian McCaffrey – 17 rushes, 78 yards
- Receiving leader: Demarcus Robinson – 5 receptions, 66 yards
🔮 49ers vs. Rams prediction
San Francisco is gutted on a short week: Brock Purdy is out (toe), George Kittle remains on IR, and Jauan Jennings and Ricky Pearsall are also ruled out. That pushes more on Christian McCaffrey and a streamlined pass game with Jones, which narrows what L.A. has to defend. The Rams’ pass rush and back-end coverage can squeeze those condensed concepts, especially if they win on early downs.
On the other side, Stafford should find steady answers in the middle of the field with Nacua working the field, while Kyren Williams churns clock behind a physical interior. Even with Tyler Higbee and RT Rob Havenstein trending the wrong way, Sean McVay’s motion/play-action menu creates layups and keeps the chains moving.
🦅 Eagles (-3.5) vs. Broncos
| Team | 1Q | 2Q | 3Q | 4Q | Final |
|---|---|---|---|---|---|
| Broncos | 3 | 3 | 7 | 3 | 16 |
| Eagles | 7 | 10 | 7 | 6 | 30 |
🔢 Eagles projected stats
- Passing leader: Jalen Hurts – 21/30, 255 yards, 2 TD, 1 INT
- Rushing leader: Saquon Barkley – 17 rushes, 75 yards, 1 TD
- Receiving leader: A.J. Brown – 6 receptions, 88 yards, 1 TD
🔢 Broncos projected stats
- Passing leader: Bo Nix – 24/38, 248 yards, 1 TD, 1 INT
- Rushing leader: J.K. Dobbins – 15 rushes, 64 yards
- Receiving leader: Courtland Sutton – 7 receptions, 83 yards, 1 TD
🔮 Broncos vs. Eagles prediction
Denver’s offense has perked up with a real run game behind JK Dobbins and RJ Harvey and cleaner structure for Bo Nix, but this is a step up in class against an Eagles front that wins on early downs and forces you to play one-handed. If Philly contains the zone read and keeps Sutton in front, Denver’s explosives dry up.
Philly’s offense is built to stress Denver’s young corners with isolation to A.J. Brown and layered RPOs. Saquon Barkley’s presence keeps the box honest, and Jalen Hurts’ pocket movement solves pressure. Even if Lane Johnson’s status is something to monitor, the Eagles’ multiple looks and red-zone edge carry the day.
🐴 Colts (-6.5) vs. Raiders
| Team | 1Q | 2Q | 3Q | 4Q | Final |
|---|---|---|---|---|---|
| Raiders | 3 | 7 | 3 | 7 | 20 |
| Colts | 7 | 7 | 7 | 7 | 28 |
🔢 Colts projected stats
- Passing leader: Daniel Jones – 20/32, 236 yards, 1 TD, 1 INT
- Rushing leader: Jonathan Taylor – 19 rushes, 98 yards, 1 TD
- Receiving leader: Michael Pittman Jr. – 8 receptions, 94 yards
🔢 Raiders projected stats
- Passing leader: Geno Smith – 23/36, 254 yards, 2 TD, 1 INT
- Rushing leader: Ashton Jeanty – 13 rushes, 58 yards
- Receiving leader: Jakobi Meyers – 6 receptions, 71 yards, 1 TD
🔮 Raiders vs. Colts prediction
Indy’s run game is the fulcrum here. With Jonathan Taylor healthy and the Colts’ guards capable of generating double-teams on early downs, Shane Steichen can stay balanced and pick matchups for Michael Pittman Jr. and Josh Downs off play-action. Daniel Jones benefits when he’s throwing on schedule and inside the numbers.
The Raiders have answers - Smith distributes well and the tight end room is a red-zone problem - but Indy’s front (DeForest Buckner + Laiatu Latu) can force the one negative play that flips a drive. In a script where the Colts lead for most of the afternoon, Jeanty’s touches skew underneath and time becomes the enemy.
🟢 Seahawks (-3.5) vs. Buccaneers
| Team | 1Q | 2Q | 3Q | 4Q | Final |
|---|---|---|---|---|---|
| Buccaneers | 3 | 3 | 7 | 0 | 13 |
| Seahawks | 3 | 10 | 7 | 3 | 23 |
🔢 Seahawks projected stats
- Passing leader: Sam Darnold – 20/31, 227 yards, 2 TD, 1 INT
- Rushing leader: Kenneth Walker III – 16 rushes, 72 yards
- Receiving leader: Jaxon Smith-Njigba – 6 receptions, 77 yards, 1 TD
🔢 Buccaneers projected stats
- Passing leader: Baker Mayfield – 21/34, 228 yards, 1 TD, 1 INT
- Rushing leader: Rachaad White – 14 rushes, 58 yards
- Receiving leader: Chris Godwin – 7 receptions, 82 yards, 1 TD
🔮 Buccaneers vs. Seahawks prediction
With Bucky Irving in a walking boot and uncertain for Sunday, Tampa Bay likely pivots to more Baker Mayfield dropbacks and Rachaad White on early downs. That’s a tough template in Seattle, where the pass rush can play fast at home and corners rally to the flat. Expect heavier two-high from the Seahawks to cap explosives and bait throws underneath.
Seattle’s offense under Klint Kubiak has lived on rhythm throws and quick-game spacing. Sam Darnold gets defined reads, and Kenneth Walker’s cut-back ability punishes overpursuit. JSN is the chain-mover; shots come off play-action when Tampa Bay rotates late.
🦬 Bills (-8.5) vs. Patriots
| Team | 1Q | 2Q | 3Q | 4Q | Final |
|---|---|---|---|---|---|
| Patriots | 7 | 3 | 0 | 7 | 17 |
| Bills | 10 | 7 | 10 | 3 | 30 |
🔢 Bills projected stats
- Passing leader: Josh Allen – 23/34, 281 yards, 2 TD, 1 INT
- Rushing leader: James Cook – 14 rushes, 63 yards, 1 TD
- Receiving leader: Keon Coleman – 5 receptions, 74 yards, 1 TD
🔢 Patriots projected stats
- Passing leader: Drake Maye – 22/37, 232 yards, 1 TD, 2 INT
- Rushing leader: Rhamondre Stevenson – 15 rushes, 61 yards
- Receiving leader: Stefon Diggs – 6 receptions, 79 yards, 1 TD
🔮 Patriots vs. Bills prediction
Buffalo is the AFC’s last unbeaten for a reason: the Josh Allen-to-Keon Coleman / Khalil Shakir combination has been efficient on early downs, and the Bills can toggle seamlessly between spread looks and heavy play-action. That stresses a Pats defense still shuffling personnel and leaning on young corners. If Buffalo protects reasonably well, Allen’s second-reaction throws are the separator.
New England’s best shot is muddying the picture with simulated pressures and leaning on Rhamondre Stevenson to stay ahead of the sticks. But if Drake Maye faces long third downs against a Bills group that can heat you with Greg Rousseau and Ed Oliver and spin the safeties late, mistakes follow.
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