🏀 Louisville vs. Duke Prediction & Odds: Women's College Basketball Picks Today (March 8)

The ACC Championship game features a rematch between No. 12 Louisville and No. 13 Duke, with a spot in the NCAA Tournament on the line.

My best Louisville vs. Duke prediction for today's 1 p.m. ET (ESPN) game at Gas South Arena in Duluth, Ga., focuses on the great defensive play of both teams entering this contest. Duke is favored by 1.5, but in my final score prediction, I back Louisville to get the win, despite losing 59-58 at home against Duke earlier this year. 

🏀 Louisville vs. Duke picks & odds today: March 8

See all of our experts' college basketball picks based on the latest college basketball odds; picks rated on a 1-to-5 star confidence scale based on betting value.

Total wagered: 4.5 units | Max profit: 4.12 units

💰 Louisville vs. Duke prediction & best bet

Under 133.5 (-110)

These are two of the best defensive teams in the country, with Louisville allowing 60.5 points per game and Duke giving up just 58.7. The first meeting between these two featured just 117 points.

Duke has scored 69 or fewer in four of its last five games, holding three of its last five opponents to 53 or fewer. Louisville has continued its great defensive play, but has also been slowed down offensively of late, scoring 69 or fewer in three of its last four.

DraftKings is offering Under 133.5 for -110. I'd play this as low as 130.5.

Score prediction: Louisville 64, Duke 61

🔥 Best Louisville vs. Duke team prop bet

Duke Under 67.5 (-113)

Duke has struggled offensively at the ACC Tournament. Last night, Duke scored just 65 against Notre Dame, and two days ago, the Blue Devils scored just 60 against Clemson. Both opponents are allowing fewer than 65.0 points per game, and the results show that Duke's offense isn't capable of scoring much against really good defenses.

The Cardinals have held 11 of their last 12 opponents to 67 or fewer points. Duke may be averaging 74.3 points per game, but the Blue Devils have only topped that number in two of their eight games against ranked teams this season.

FanDuel is offering Under 67.5 for -120. The number is probably going to drop to 66.5 soon, which doesn't worry me at all. I'd play this as low as 64.5.

🚀 Louisville vs. Duke same-game parlay

No matter who wins this game, it's going to be a low-scoring affair. As I've already highlighted, both of these defenses are great, and the offenses have struggled against good competition. And while Duke won at Louisville earlier this season, there is more value in backing Louisville, especially after the Blue Devils' poor performance against Notre Dame yesterday.

💡 How I'm betting Louisville vs. Duke

Follow all of our college basketball analysis and expert predictions this season.

I'm allocating 4.5 units for this game, mainly because I love multiple Unders. Setting this total at 133.5 when the first meeting only featured 117 points makes no sense. Duke has scored fewer than 70 in three consecutive games and is now tasked with facing one of the best defenses in the country while also playing its third game in as many days.

While I think Louisville wins this game, I'm only willing to risk one unit because the Cardinals are just 3-2 down the stretch and have already lost to Duke at home.

📊 Live Louisville vs. Duke odds

Duke opened as 2.5-point favorites, but the public quickly backed Louisville, dropping the spread to 1.5. I wouldn't be surprised if this went off as a pick-em, especially with Louisville ranked higher entering this neutral-site game. As for the total, it opened at 133.5, and while it has stayed there at DraftKings, it's dropped to 132.5 at FanDuel. Because of the score of the first game between these two, I expect the total to continue dropping.

📈 Louisville vs. Duke betting trends

📺 How to watch Louisville vs. Duke

• Date: Sunday, March 8
• Tipoff: 1 p.m. ET
• Location: Gas South Arena (Duluth, Ga.)
• TV: ESPN