🏀 Clemson vs. Duke Prediction: ACC Semifinals Odds & Picks (March 13)

With both Duke and Clemson surviving in 80-79 wins in the ACC Quarterfinals, our Clemson vs. Duke prediction for the ACC Semifinals expect another tight affair between two slow-paced offensive teams. The action tips off from Spectrum Center in Charlotte, N.C., Friday at 9:30 p.m. ET (ESPN2).

With Duke as a double-digit favorite, we see value on the Clemson side in a game that could see limited possessions. Cameron Boozer's rebounding efforts could be on display given Duke's defensive efficiency to force missed shots.

🏀 Clemson vs. Duke picks & odds: ACC Semifinals (March 13)

See all of our experts' college basketball picks based on the latest college basketball odds; picks rated on a 1-to-5 star confidence scale based on betting value.

Total wagered: 3.26 units | Max profit: 3.0 units

💰 Clemson vs. Duke prediction & best bet

Under 133.5 (-110)

Duke and Clemson met once during the regular season, with the Blue Devils winning at home in an affair that totaled just 121 points (67-54). This rematch on a neutral floor could favor another low-scoring output despite both teams playing in games that saw 159 total points on Thursday.

Thursday's games came against teams that run faster tempos, while Duke and Clemson is destined to be a chess match with adjusted tempos of 293rd and 336th, respectively. Duke ranks 1st in the nation in adjusted defensive efficiency, with Clemson at a respectable 19th, leading to my belief that the rock fight in Durham earlier in the year was no fluke.

Score prediction: Duke 68 - Clemson 60

🔥 Best Clemson vs. Duke player prop bet

Cameron Boozer Under 10.5 rebounds (-110)

There's risk in fading Cameron Boozer's rebounding output as he should pace Duke's 5th-ranked total rebounding rate (57.8%) against a Clemson team that I don't expect to post an efficient field-goal percentage against Duke's top-tier defense. But Boozer has only cleared this rebounding total in 14 of 32 games this season (43.75%), below the implied probability of 52.38% at -110 odds.

He also recorded only eight rebounds in this matchup earlier in the year, despite Clemson shooting only 35.1% from the floor. The Tigers' low-shooting percentage didn't lead to more rebounding chances because of the low number of possessions in the game.

We expect a repeat of this trend on Friday and lean toward targeting Under as we believe Boozer's name-recognition has contributed to this line being listed higher than his 10.2 rebounds per game average.

🚀 Clemson vs. Duke same-game parlay

Clemson keeping the game close against Duke on a neutral floor is likely an outcome that would correlate to a low overall point total due to the defensive strengths of these teams and their respective measured offensive tempos. A game with a low possession count could lead to a quieter rebounding output for a marquee name like Boozer, which lends itself toward juicier parlay odds than if we had bet Boozer's rebounding prop Over.

💡 How I'm betting Clemson vs. Duke

Follow all of our college basketball analysis and expert predictions this season.

I'm keeping my wagers on this matchup at one unit per bet. Although we have the most confidence in Under 133.5 as a four-star play, keeping consistent unit sizes is a key to success in the heavy-volume month of March.

📊 Live Clemson vs. Duke odds: ACC Semifinals

After Duke's narrow survival over Florida State, the public seems to be hesitant to back the Blue Devils on such a large spread, seeing the line move from Duke -11.5 down to -10.5. 

📈 Clemson vs. Duke betting trends

📺 How to watch Clemson vs. Duke: ACC Semifinals

• Date: Friday, March 13
• Tipoff: 9:30 p.m. ET
• Location: Spectrum Center (Charlotte, N.C.)
• TV: ESPN2
• Streaming: ESPN+