NBA Against the Spread Picks & Predictions Today: Best Bets for Tuesday, May 6

Gabe Henderson makes his best NBA against the spread picks and predictions for Tuesday's NBA playoffs second-round action.

Gabe Henderson

Last Updated: May 6, 2025 1:49 PM EDT • 3 minute read

NBA Predictions Against the Spread Today: Expert ATS Picks for Tuesday, May 6 — Pictured: Golden State Warriors guard Stephen Curry (30) dribbles the ball against Minnesota Timberwolves forward Jaden McDaniels (3). Photo by Jesse Johnson via Imagn Images.

Our NBA picks and predictions against the spread highlight our best bets ahead of today's NBA playoffs action featuring Pacers vs. Cavaliers and Warriors vs. Timberwolves.

🏀 Best NBA predictions against the spread today: Tuesday, May 6

✅ Cavaliers (-8.5) vs. Pacers (-115 via ESPN BET) ⭐⭐⭐
✅ Warriors (+7) vs. Timberwolves (-110 via Caesars) ⭐⭐⭐⭐

💰 NBA ATS picks & best bets for Tuesday

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🔥 Cavaliers (-8.5) vs. Pacers ⭐⭐⭐

Cleveland was scorching to start the playoffs while sweeping the Miami Heat, averaging a 30.5-point margin of victory. The Cavaliers covered an 8.5-point spread in all four outings, showcasing their prowess at both ends of the floor under NBA Coach of the Year odds winner Kenny Atkinson.

The Pacers have been tough opponents for Cleveland this year, with the latter winning just once against Indiana. However, the lone win featured the NBA's best ATS team (55-36-1) notching a double-digit triumph.

We're betting on the Cavaliers to get their revenge tonight.

✅ Best odds: -115 via ESPN BET (bet $10 to win $8.70 profit)

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🔥 Warriors (+7) vs. Timberwolves ⭐⭐⭐⭐

This line is giving the hosts a bit too much credit after they beat a flawed Los Angeles Lakers team. The Timberwolves were exploiting the Lakers' weaknesses throughout the back half of the series, picking on size disadvantages in the paint.

However, those obvious holes don't exist within Golden State's roster.

The Warriors are not only more well-equipped to hang with Minnesota, but they're also the most experienced team remaining. Steve Kerr's squad has been a road underdog 24 times this season while posting a 14-10 ATS record. That includes two outright wins in Houston.

Expect Stephen Curry and Co. to keep it close.

✅ Best odds: -110 via Caesars (bet $10 to win $9.09 profit)

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💡 More NBA expert picks

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Written by:
Gabe Henderson

Gabe Henderson is a sports betting writer from Houston, Texas. He graduated from Louisiana State University in 2022 with a bachelor's degree in Mass Communication. Gabe developed an interest in sports betting while in college due to its legalization in Louisiana. He turned his passion into a career shortly after, joining The Advocate/NOLA.com as a Sports Betting Content Coordinator, where he spent two years. Gabe wore many hats before graduating as he led FanSided's coverage of Chelsea FC as a Site Expert with "The Pride of London." He was also the Editor-in-Chief of the LSU Gumbo Yearbook for two years. Gabe became a part of the SportsbookReview.com team in late 2024. He brings with him an extensive knowledge of many sports, including — but not limited to — NFL, NCAA, MLB, NBA, soccer, and UFC.