Lions vs. Tiger-Cats Prediction, Odds & CFL Best Bets: Aug. 7

Last Updated: August 7, 2025 7:00 AM EDT • 4 minute read X Social Google News Link

Two of the best QBs in the CFL meet tonight as the Hamilton Tiger-Cats host the BC Lions at 7:30 p.m. ET (TSN/RDS2, CBSSN) from Hamilton Stadium. My Lions vs. Tiger-Cats prediction expects both Nathan Rourke and Bo Levi Mitchell to shine as they attempt to bolster their teams' Grey Cup odds.
🔮 Lions vs. Tiger-Cats expert picks & predictions
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✅ Moneyline pick: Tiger-Cats (-156 via FanDuel) ⭐⭐
✅ Against the spread pick: Tiger-Cats -3 (-102 via DraftKings) ⭐⭐⭐
✅ Over/Under pick: Over 55.5 (-110 via Caesars) ⭐⭐⭐⭐
🆚 Who will win Lions vs. Tiger-Cats?
✅ Moneyline pick: Tiger-Cats will win (-156 via FanDuel)
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No offense in the CFL is hotter right now than Hamilton's after Mitchell led the Tiger-Cats past the Edmonton Elks with a last-minute touchdown pass last week following a weather delay. Despite Hamilton's clunky defense, the Tiger-Cats have now won six games in a row behind the play of Mitchell, who leads the CFL Most Outstanding Player odds.
Meanwhile, the Lions have looked stagnant at 3-5, and prior to their Week 9 bye, they suffered a 37-33 loss to Hamilton at home. I'm expecting much of the same in the Hammer with my Lions vs. Tiger-Cats prediction projecting Hamilton to win by a score of 34-27.
💰 Lions vs. Tiger-Cats prediction & CFL best bet

🚀 Over 55.5 ⭐⭐⭐⭐
📊 Best odds: -110 via Caesars ($10 to win $9.09)
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The Tiger-Cats are like a Mike Leach-led Texas Tech team right now in the old Big 12. They have to win every week by leaning on their passing game and airing it out for four quarters to make up for their less-than-stellar defense.
It's helped make Hamilton the most fun team in the league to watch - and one of the best teams to back for Over bettors. The Tiger-Cats lead the league in points per game (31.6) but have allowed 28-plus points four times.
With this same game total against BC two weeks ago (55.5), the teams cruised past it, combining for 70 points. Mitchell was unstoppable, throwing for 389 and three scores, while Rourke was efficient, throwing for 289 with a 74% completion rate as CFL leading rusher James Butler popped off for 115 on the ground.
The Lions are allowing 27 points per game, and Hamilton is not much better at 26.6; both QBs should have another strong outing in their rematch. Thanks to two of the deepest receiving corps in the CFL, neither defense is equipped to keep this one low-scoring.
👀 Star player prop to watch
🐯 Bo Levi Mitchell Over 300.5 passing yards ⭐⭐⭐⭐
📊 Best odds: -135 via DraftKings ($10 to win $7.41)
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It's understandable why this line is set this low; the Lions give up the fewest passing yards per game in the CFL (225.8). But Mitchell torched them for a season-high 389 last week and leads the CFL in passing yards (2,551) and passing touchdowns (18) while sitting second in QB rating (110.7). Stopping this Hamilton passing attack is a whole other beast.
The two-time CFL MOP has thrown for Over 300.5 passing yards in six of eight games this season. He's separated himself as the CFL MOP favorite over the last three contests, clearing this total in each one while averaging 355.3 passing yards per game.
🏈 Lions vs. Tiger-Cats odds
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Rob Paul X social