⚾ Yankees vs. Giants Prediction & Picks: MLB Odds for Friday, March 27

My Yankees vs. Giants prediction breaks down the best bets, player props, home run pick, and same-game parlay I’m betting today.
New York Yankees second baseman Jazz Chisholm Jr. headlines our Yankees vs. Giants predictions for this afternoon showdown.
Pictured: New York Yankees second baseman Jazz Chisholm Jr. headlines our Yankees vs. Giants predictions for this afternoon showdown. Photo by Nathan Ray Seebeck via Imagn Images.
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The New York Yankees dominated MLB's Opening Night game on Netflix, smashing the San Francisco Giants 7-0. The home team will be out for revenge today at 4:35 p.m. ET at Oracle Park (ESPN Unlimited), with Robbie Ray taking the hill opposite Cam Schlittler for the visitors.

My Yankees vs. Giants prediction expects both starters to be in tough, as I'm betting on plenty of scoring. The Yankees are once again small moneyline favorites, but I'm forgoing picking an outright winner and instead looking at a pair of intriguing player props along with the game total, which is set at 8.


⚾ Yankees vs. Giants picks & odds today

See all of our experts’ MLB picks based on the latest MLB odds; picks rated on a 1-to-5 star confidence scale based on betting value.

⚾ Pick 💵 Units 📝 Notes
Over 8 (-118 via DraftKings) 1u → 1.93u Giants' offense should bounce back from being shut out
Jazz Chisholm Over 1.5 total bases (+205 via bet365) 0.67u → 2.04u Value thanks to lefty-lefty matchup
Rafael Devers home run (+425 via BetMGM) 0.33u → 1.73u Historically owns the Yankees and hit a rocket in opener

Total wagered: 2 units | Max profit: 3.7 units

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🏆 Who will win Yankees vs. Giants?

I backed the Giants to win the season opener and, well, we know how that went. Maybe I gave San Francisco's offense too much credit, but I do think it wakes up a bit in this game now that it's not facing AL Cy Young contender Max Fried

However, I don't think it'll be enough to beat the Yankees today. After a hilariously poor showing at the plate, Aaron Judge should contribute at least something, and I expect Giancarlo Stanton and Jazz Chisholm to stay hot.

Score prediction: Yankees 6, Giants 4


💰 Yankees vs. Giants prediction & best bet

Over 8 (-118 via DraftKings)

The Yankees nearly went Over this total on their own in the first game, and that was with Logan Webb starting for the Giants. Now that the two Cy Young contenders have pitched, we should see even more offense in this afternoon game at Oracle Park.

A couple of the best sports betting sites have this total listed at 8.5 at better odds, but I'll opt to take the Over on 8 so we have the chance to push in case Judge and the Giants' offense once again show up half-asleep for this one.

📡 SBR Edge: Much more exploitable pitching matchup in Game 2

While Webb didn't have his best stuff, he still did an admirable job of limiting the damage compared to how bad it could have been. I don't anticipate Ray and Schlittler having as much success today.


🔥 Best Yankees vs. Giants player prop bet

Jazz Chisholm Over 1.5 total bases (+205)

We're seeing an edge on this one, likely due to the lefty-lefty matchup. However, that doesn't scare me off, and the projections suggest it opens up a very lucrative betting opportunity.

Based on Chisholm's projections for this afternoon's game, we're getting better than 25% +EV on him to go Over 1.5 total bases. As was the case with Stanton on Wednesday night, the Over 1.5 is the higher EV play than Over 0.5 at minus money. Though if you can find a -125 or -130 for Over 0.5 bases, I don't hate that.


💣 Yankees vs. Giants home run prediction

Rafael Devers home run (+425)

There's a ton of hype surrounding Schlittler, but I'm not completely sold on him yet. You can get away with pumping in fastball after fastball as a starting pitcher for only so long, and I think he gets a bit of a rude awakening in his first start of the season now that teams have more tape on him.

Rafael Devers absolutely smoked a liner in MLB's Opening Night game, and I think he gets the launch angle right this afternoon and lifts it out of Oracle Park. Based on his projection, we're getting better than 43% +EV on this home run bet. Even DraftKings' low price of +363 still profiles as a good bet, though I wouldn't play this at anything shorter than +335.

I also backed Devers as part of my home run predictions today.


🚀 Yankees vs. Giants same-game parlay

I'm going to stick with my theme of a higher-scoring game and parlay the Over 8.5 with Devers and Chisholm to record two-plus total bases each, and also add Ray to go Under his strikeout total.

💵 Yankees vs. Giants SGP picks

  • Over 8.5 (-102)
  • Jazz Chisholm 2+ bases (+180)
  • Rafael Devers 2+ bases (+130)
  • Robbie Ray Under 5.5 strikeouts (+114)

Best odds: +1571 via FanDuel (0.2u -> 3.35u)


💵 My betting record for MLB picks

All MLB picks have been tracked since March 25.

Bet type Record Net profit ROI
Overall 1-6 -3.55 units ❌ -66.7% ❌
Home run picks 0-2 -0.67 units ❌ -100% ❌
Other batter props 1-1 +0.11 units ✅ +6.3% ✅

💡 How I'm betting Yankees vs. Giants: MLB strategy

Follow all of our MLB analysis and expert predictions for baseball season.

As you can see above, I'm betting fairly conservatively when it comes to this game. I don't mind betting a full unit on the game to go Over its total, but then I prefer to split a unit between the two player props.

I limit all of my home run wagers to 0.33 units, so I'll combine that with 0.67 on Chisholm's total bases Over to end up with two total units wagered.


📊 Live Yankees vs. Giants odds

These odds are pretty similar to those from the Opening Night game between these two teams, with the Giants listed as a slightly bigger underdog for Friday's contest. Bettors at DraftKings are once again all over the Yankees, as 82% of moneyline bets have come in on the favorites. They're also expecting a high-scoring game like I am, as 79% of bets on the total have come in on the Over.


📈 Yankees vs. Giants betting trends

Yankees Statistic Giants
1-0 W-L record 0-1
1-0 Run line record 0-1
0-0 O/U record 0-0
0.00 Team ERA 6.00
.278 Team batting avg. .097
.683 OPS .273

🚑 Yankees vs. Giants injuries


📺 How to watch Yankees vs. Giants today

  • Date: Friday, March 27
  • First pitch: 4:35 p.m. ET
  • Ballpark: Oracle Park (San Francisco)
  • TV: ESPN Unlimited, YES Network, NBC Sports Bay Area
  • Streaming: MLBTV
  • Yankees starter: Cam Schlittler (4-3, 2.96 ERA in 2025)
  • Giants starter: Robbie Ray (11-8, 3.65 ERA in 2025)