Yankees vs. Blue Jays Prediction, Odds & Best Bets: Toronto's Win Streak Subsists

Toronto looks to extend its franchise-record win streak at home against an AL East rival in New York.

Gabe Henderson

Last Updated: July 22, 2025 2:16 PM EDT • 4 minute read

Yankees vs. Blue Jays Prediction, Odds & Best Bets: Tuesday, July 22 — Pictured: Toronto Blue Jays relief pitcher Jeff Hoffman (23) reacts as we make our Yankees vs. Blue Jays prediction for Tuesday, July 22. Photo by Nick Turchiaro via Imagn Images.

The Toronto Blue Jays (59-41) set a franchise record for consecutive home wins in their series opener against the New York Yankees (55-45), and my Yankees vs. Blue Jays prediction expects the hosts to extend that streak tonight.

The Blue Jays are -120 betting favorites at the best sports betting sites as they look to improve upon their MLB-best record at home. First pitch from Rogers Centre in Toronto is set for 7:07 p.m. ET (SportsNet, YES Network).

My Yankees vs. Blue Jays best bets look for one of New York's coldest hitters to break out tonight, regardless of the overall result.

Yankees vs. Blue Jays prediction: Blue Jays to win (-120 via BetMGM) ⭐⭐⭐⭐
Best Yankees vs. Blue Jays player props: Anthony Volpe Over 0.5 doubles (+450 via bet365) ⭐⭐

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✅ Yankees vs. Blue Jays prediction: Blue Jays to win (-120 via BetMGM)

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My Yankees vs. Blue Jays prediction sees the host staying hot at home behind a surefire future Hall of Fame starter in Max Scherzer, who's highlighted in our best strikeout props today. The veteran struck out seven New York batters across five innings of two-run baseball during his only outing against the Yankees three weeks ago.

The visitors combat this move by sending out Cam Schlittler (5.06 ERA), whom we have a hard time imagining will succeed in a raucous environment at Rogers Centre.

Aaron Boone is lucky this game is being played in Canada. Throwing a 24-year-old with one career start to the wolves against a red-hot Toronto lineup is a direct violation of the Eighth Amendment to the United States Constitution - it's cruel and unusual punishment.

My Yankees vs. Blue Jays best bet will continue to back the Blue Jays until the AL East leaders give me a reason to fade them. Toronto is trading at -120 with our best sports betting apps to continue its hot streak. We recommend this play at four-star confidence.

💰 Best Yankees vs. Blue Jays player prop

✅ Best Yankees vs. Blue Jays player prop: Anthony Volpe Over 0.5 doubles (+450 via bet365)

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Scherzer has historically fared well against most of New York's lineup. Jazz Chisholm (.250), Paul Goldschmidt (.205), Aaron Judge (.250), and Giancarlo Stanton (.259) have all struggled to hit the starter. Oddly enough, Anthony Volpe - who is currently hitting .214 this season - has found success versus Scherzer.

Volpe's tallied two hits across four career at-bats against the 40-year-old. Both went for extra bases, and even more specifically, they were doubles off the right-hander.

My best Yankees vs. Blue Jays player prop takes a flier on Volpe to club his third double against Scherzer at a fantastic price. BetMGM and bet365 are the best sportsbooks to shop at for this play with a winning $10 wager profiting $45.

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Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common.

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Written by:
Gabe Henderson

Gabe Henderson is a sports betting writer from Houston, Texas. He graduated from Louisiana State University in 2022 with a bachelor's degree in Mass Communication. Gabe developed an interest in sports betting while in college due to its legalization in Louisiana. He turned his passion into a career shortly after, joining The Advocate/NOLA.com as a Sports Betting Content Coordinator, where he spent two years. Gabe wore many hats before graduating as he led FanSided's coverage of Chelsea FC as a Site Expert with "The Pride of London." He was also the Editor-in-Chief of the LSU Gumbo Yearbook for two years. Gabe became a part of the SportsbookReview.com team in late 2024. He brings with him an extensive knowledge of many sports, including — but not limited to — NFL, NCAA, MLB, NBA, soccer, and UFC.