Twins vs. Tigers Prediction Tonight: Best Bets & Odds for Minnesota vs. Detroit
Last Updated: August 4, 2025 5:00 PM EDT • 4 minute read X Social Google News Link
Detroit's looked like a shell of its former self since the All-Star break, but my Twins vs. Tigers prediction expects the hosts to get back on track beginning with tonight's American League Central contest.
First pitch is set for 6:40 p.m. ET (Twins.TV, FDSN Detroit) from Comerica Park in Detroit. The Tigers are -189 betting favorites at the best sports betting sites, with a total of O/U 8.5 runs.
My Twins vs. Tigers best bets anticipate starting pitcher Casey Mize to lead the Tigers to victory tonight against Minnesota's makeshift lineup.
- Twins vs. Tigers prediction: Tigers to win (-160 via BetMGM) ⭐⭐⭐⭐
- Best Twins vs. Tigers player props: Casey Mize Over 4.5 strikeouts (-112 via FanDuel) ⭐⭐⭐
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🧐 Twins vs. Tigers betting insights
The latest Twins vs. Tigers betting insights are from BetMGM as of Monday evening.
| Team | Run Line | Moneyline | Total |
| Twins | 18% (+1.5, -130) | 11% (+155) | 58% (Over 8.5, -110) |
| Tigers | 82% (-1.5, +110) | 89% (-190) | 42% (Under 8.5, -110) |
💰 Twins vs. Tigers prediction & best bet
✅ Twins vs. Tigers prediction: Tigers to win (-160 via BetMGM)
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My Twins vs. Tigers prediction confidently chooses the hosts to get back into the win column tonight. Detroit is a mediocre 5-5 over its last 10, but Minnesota has been one of the league's worst teams at 3-7 over the same span. The only teams with worse records recently are the Houston Astros and Tampa Bay Rays.
The Twins' struggles only compound on the road, where they've lost seven of their last 10 games straight up. This rough stretch includes losses in five straight series overall. It truly puts Detroit's slump into perspective and shows things can always get worse.
A.J. Hinch hands the ball to an All-Star, Mize, to get the job done tonight. On the other side of the aisle, the Twins' pitching plan remains under wraps. The Tigers have taken four of six from Minnesota this season, including a 1-1 clip with Mize on the mound. The starter was stellar in his last outing against these opponents.
My Twins vs. Tigers best bet believes Detroit gets back to winning ways against what remains of a heavily depleted Minnesota roster. The best sports betting apps concur, with BetMGM offering the shortest moneyline odds (-160).
💰 Best Twins vs. Tigers player props
✅ Best Twins vs. Tigers player prop: Casey Mize Over 4.5 strikeouts (-112 via FanDuel)
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I've already alluded to Mize's success in his last start against the Twins. He picked up his eighth win of the season, tossing 6 2/3 frames of two-run baseball, punching out five in the process. He's sat down eight Minnesota hitters in two starts, but my Twins vs. Tigers player prop expects him to go Over his total tonight.
The Twins' fire sale at the trade deadline stripped the team of nearly all of its proven talent. With all due respect to Minnesota's 26-man roster, it now essentially consists of Byron Buxton - who hasn't played since July 26 - and an amalgamation of quadruple-A players. Unfortunately, that reflects in the team's stats.
Rocco Baldelli's boys lead the league in strikeouts over the last three games (13.67 per game), three more than the next-worst teams, Seattle and St. Louis (10.67 per game). Therefore, Mize should have no issue reaching his strikeout tally from his last start against Minnesota, a play that comes at a -112 price with the best sportsbooks.
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❓MLB betting FAQs
How do betting odds work?
Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common.
What is the run line in baseball?
The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.
What does moneyline mean in betting?
The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet - just pick the winner.
💵 Best MLB betting sites
Want to bet on Twins vs. Tigers? Check out the best MLB betting sites and best sportsbook promos for today's MLB games:
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