Twins vs. Tigers Prediction, Odds & Best Bets: Casey Mize Cuts Down Minnesota

After a tough series in Philadelphia, the Tigers return home tonight as heavy favorites against the new-look Twins.
Twins vs. Tigers Prediction, Odds & Best Bets: Monday, Aug. 4
Pictured: Detroit Tigers pitcher Casey Mize (12) throws as I make my Twins vs. Tigers prediction. Photo by Junfu Han / USA TODAY NETWORK via Imagn Images.

Detroit's had a tough time since returning from the All-Star break, but my Twins vs. Tigers prediction expects a relatively simple series for the class of the American League Central.

The Tigers are -160 betting favorites at the best sports betting sites, with a total set at O/U 8.5 runs. First pitch from Comerica Park in Detroit is scheduled for 6:40 p.m. ET (Twins.TV, FDSN Detroit).

My Twins vs. Tigers best bets anticipate a Tigers victory on the back of Casey Mize, who has a chance to cut down Minnesota's makeshift lineup tonight.

  • Twins vs. Tigers prediction: Tigers to win (-160 via BetMGM) ⭐⭐⭐⭐
  • Best Twins vs. Tigers player props: Casey Mize Over 4.5 strikeouts (-112 via FanDuel) ⭐⭐⭐

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✅ Twins vs. Tigers prediction: Tigers to win (-160 via BetMGM)

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My Twins vs. Tigers prediction confidently chooses the hosts to get back into the win column tonight. Detroit is a mediocre 5-5 over its last 10, but Minnesota has been one of the league's worst teams at 3-7 over the same span. The only teams with worse records recently are the Houston Astros and Tampa Bay Rays.

The Twins' struggles only compound on the road, where they've lost seven of their last 10 games straight up. This rough stretch includes losses in five straight series overall. It truly puts Detroit's slump into perspective and shows things can always get worse.

A.J. Hinch hands the ball to an All-Star, Mize, to get the job done tonight. On the other side of the aisle, the Twins' pitching plan remains under wraps. The Tigers have taken four of six from Minnesota this season, including a 1-1 clip with Mize on the mound. The starter was stellar in his last outing against these opponents.

My Twins vs. Tigers best bet believes Detroit gets back to winning ways against what remains of a heavily depleted Minnesota roster. The best sports betting apps concur, with BetMGM offering the shortest moneyline odds (-160).

💰 Best Twins vs. Tigers player props

✅ Best Twins vs. Tigers player prop: Casey Mize Over 4.5 strikeouts (-112 via FanDuel)

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I've already alluded to Mize's success in his last start against the Twins. He picked up his eighth win of the season, tossing 6 2/3 frames of two-run baseball, punching out five in the process. He's sat down eight Minnesota hitters in two starts, but my Twins vs. Tigers player prop expects him to go Over his total tonight.

The Twins' fire sale at the trade deadline stripped the team of nearly all of its proven talent. With all due respect to Minnesota's 26-man roster, it now essentially consists of Byron Buxton - who hasn't played since July 26 - and an amalgamation of quadruple-A players. Unfortunately, that reflects in the team's stats.

Rocco Baldelli's boys lead the league in strikeouts over the last three games (13.67 per game), three more than the next-worst teams, Seattle and St. Louis (10.67 per game). Therefore, Mize should have no issue reaching his strikeout tally from his last start against Minnesota, a play that comes at a -112 price with the best sportsbooks.

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