Tigers vs. Pirates Prediction Tonight: Best Bets & Odds as Pittsburgh Eyes Win Streak

Detroit paced MLB for much of the season before the current bad run of results, but my Tigers vs. Pirates prediction sees success on the horizon for the AL Central leaders.

The best sports betting sites list Detroit (-130) as the betting favorite, despite being dethroned atop MLB standings in recent days. First pitch is scheduled for 6:40 p.m. ET (FDSN Detroit, SportsNet-PIT) from PNC Park in Pittsburgh.

My Tigers vs. Pirates best bets expect Casey Mize to pick up his 10th win of the season, even though he likely won't stuff the stat sheet on the road.

• Tigers vs. Pirates prediction: Tigers to win (-144 via FanDuel) ⭐⭐⭐⭐
• Best Tigers vs. Pirates player props: Casey Mize Under 4.5 strikeouts (-125 via BetMGM) ⭐⭐⭐⭐

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🧐 Tigers vs. Pirates betting insights

The latest Tigers vs. Pirates betting insights are from BetMGM as of Tuesday afternoon:

💰 Tigers vs. Pirates prediction & best bet

✅ Tigers vs. Pirates prediction: Tigers to win (-144 via FanDuel)

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Detroit is entering uncharted territory. The Tigers have lost seven of their last eight on either side of the All-Star break, an unprecedented stretch this season from the AL Central leaders. However, with first-time All-Star Mize on the mound tonight, A.J. Hinch's group could get back on track.

My Tigers vs. Pirates prediction expects the visitors to rally behind Mize, who has allowed two or fewer earned runs in four of his last five starts. The 28-year-old was efficient against Pittsburgh last month, allowing just five hits and two runs across six frames.

As much as my Tigers vs. Pirates best bet is about Detroit rallying behind its All-Star starter, I'm also fading the Pirates in this spot.

Paul Skenes - the big winner in yesterday's series opener - and Mitch Keller have yet to win when pitching consecutive contests. Pittsburgh is 0-4 with Keller on the bump following a Skenes win. Oddsmakers are clearly aware of the trend, as well, but we're comfortable laying the juice with Detroit in this bounceback spot.

💰 Best Tigers vs. Pirates player props

✅ Best Tigers vs. Pirates player prop: Casey Mize Under 4.5 strikeouts (-125 via BetMGM)

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As I alluded to above, it's been a campaign to celebrate for Mize, who appeared in his first All-Star Game over the break. He's in line to pick up his 10th win of the season tonight, and a good performance could see his ERA dip below 3.00 during this career year.

All of that being said, Mize is tied for 79th in strikeouts with 77 punchouts across 16 appearances. He's gone Under 4.5 strikeouts in four of his last seven outings, including the last two. The veteran only notched four strikeouts against a Seattle team that strikes out at a higher clip than all but three MLB teams.

My best Tigers vs. Pirates player prop expects Mize to struggle in the strikeout department, despite picking up the win. This prop is juiced at all of our best sports betting apps, but BetMGM's -125 price provides much more value than DraftKings (-145).

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❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common. 

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet - just pick the winner.

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