Phillies vs. Yankees Prediction Tonight: Best Bets & Odds for Interleague Bout

New York and Philadelphia have slowed down after scorching hot starts to the season, but our Phillies vs. Yankees prediction expects the hosts' bats to come alive in tonight's interleague contest.

First pitch from Yankee Stadium in the Bronx, N.Y., is scheduled for 7:05 p.m. ET (Apple TV+). Our best sports betting sites list New York as a -162 betting favorite, with Philadelphia priced at +140. 

My Phillies vs. Yankees best bets fade the visitors' starter after he struggled in his last outing against an American League side.

• Phillies vs. Yankees prediction: Yankees to win (-155 via bet365) ⭐⭐⭐⭐
• Best Phillies vs. Yankees player props: Taijuan Walker Over 4.5 hits allowed (-141 via Caesars) ⭐⭐⭐⭐⭐

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✅ Phillies vs. Yankees prediction: Yankees to win (-155 via bet365)

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My Phillies vs. Yankees prediction gives the hosts the upper hand due to a superior offense and a more favorable pitching matchup. Taijuan Walker gets the nod for Philadelphia, and while he's been solid recently in a reduced reliever role, the hurler has been struggling throughout his career against New York.

Walker is 2-4 with a 4.47 ERA across nine career starts versus the Yankees. His last trip to Yankee Stadium in 2023 resulted in him posting an 8.31 ERA after giving up four earned runs across 4 1/3 innings. Taking past performances into account, our best sports betting apps are heavily juicing Walker's odds to surrender Over 2.5 earned runs tonight.

Aaron Boone's men score at an elite clip. Their 5.20 runs per game average is elevated to 5.31 at home, whereas Philadelphia's form dips on the road (5.12 runs per game at home to 4.06 on the road). Thus, giving the hosts a favorable pitching matchup isn't an ideal formula for winning in the Bronx.

If the Phillies want a puncher's chance, Kyle Schwarber needs to take advantage of the short porch, as Sean Tomlinson discusses in the best home run predictions today. However, my Phillies vs. Yankees best bet backs the hosts to win comfortably, thanks to their historically hot bats.

💰 Best Phillies vs. Yankees player props

✅ Best Phillies vs. Yankees player prop: Taijuan Walker Over 4.5 hits allowed (-141 via Caesars)

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The value has been stripped from Walker's earned runs market, so I'm opting to play his hits allowed instead. The veteran gave up nine hits over four innings of work in his last start against the Angels. Meanwhile, the Yankees' hitters are practically enjoying batting practice against Walker.

Here's a look at the career averages for some of New York's everyday starters against the Philadelphia pitcher:

• Cody Bellinger: .273 (6-for-22)
• Jazz Chisholm: .467 (7-for-15)
• Paul Goldschmidt: .385 (5-for-13)
• Trent Grisham: .429 (3-for-7)
• Aaron Judge: .308 (4-for-13)
• Giancarlo Stanton: .333 (4-for-12)

Chisholm - who has performed the best against Walker - is heating up with hits in six of his last 10 starts.

All of this is to say that as long as Walker gives the visitors some length, the Bronx Bombers' bats should come alive. My best Phillies vs. Yankees player prop predicts that Walker will give up more than 4.5 hits at a -141 price point with the best sportsbooks.

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❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common. 

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet - just pick the winner.

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