Mariners vs. Astros Predictions, Odds & Expert Picks for Sunday Night Baseball

It does not get much bigger than Sunday Night Baseball between the Seattle Mariners and Houston Astros, with Houston looking to trim Seattle’s lead in the AL West to one game with six to play.

Seattle is red hot, having won 13 of its last 14 games, but my Mariners vs. Astros prediction, part of the MLB picks, backs Houston to avoid the sweep at home at 7:10 p.m. ET (ESPN) from Daikin Park in Houston.

The Mariners are the -140 moneyline betting favorite.

Astros leadoff man Jeremy Pena has been a sparkplug for the offense all season, and a pair of his teammates’ previous successes against today’s starting pitcher are significant reasons for my Mariners vs. Astros best bets for Sunday Night Baseball.

🔢 Mariners vs. Astros odds & betting lines

Here are the latest Mariners vs. Astros odds and betting lines from our best live betting sites.

💰 Best Mariners vs. Astros predictions: Sunday Night Baseball

Here are my best Mariners vs. Astros Sunday Night Baseball predictions for today's MLB matchup. Be sure to check out the rest of our MLB picks along with our guide on how to bet on the MLB.

📊 Who will win today's Sunday Night Baseball matchup?

As of Sunday morning, the Mariners are favored to beat the Astros in today's MLB matchup from Daikin Park in Houston (7 p.m. ET). Despite Seattle's scorching form, I'm predicting the Astros will beat the Mariners as +120 moneyline underdogs.

🎯 Best Mariners vs. Astros player props for Sunday Night Baseball

Entering Friday’s series opener, Pena had 10 hits in 24 at-bats while accumulating a 1.148 OPS over his previous six games. He also ranked in the 80th percentile in batting run value, the 93rd percentile in base-running value, and the 81st percentile in fielding run value. 

The team went just 13-14 when he missed 27 games from June 28 to July 31 with a rib fracture. However, the reason for backing the Over on his hits/runs/RBI prop is primarily predicated on the successes of two of his teammates that follow him in the batting order.

Carlos Correa and Jose Altuve each have an OPS of .951 or better against Mariners righty Logan Gilbert. The duo has combined for three home runs in 50 at-bats off Gilbert, with nine of their 17 combined hits going for extra bases.

Pena has gone over this projected total in five of his last seven games, so I am expecting him to fill up the stat sheet once again despite this low total (O/U 8 runs).

Pena has also recorded at least one RBI in five of the last six games.

The implied odds for this Over are as high as 54.13% based on -118 odds at the high end of the market, so I am backing the best price and number at DraftKings. With odds of -115, a $10 winning wager would yield $8.70 in profits. 

Best player prop: Jeremy Pena Over 1.5 hits + runs + RBI (-115 via DraftKings)

1️⃣ NRFI/YRFI bet for Sunday Night Baseball: YRFI (-105 via BetMGM)

The YRFI is 7-0 in Houston’s last seven games as home underdogs against AL West opponents, informing our Mariners vs. Astros best bets for Sunday Night Baseball.

📺 How to watch Sunday Night Baseball

⚔️ Matchup: Mariners vs. Astros
📅 Date: Sept. 21
🕗 Time: 7 p.m. ET
📍 Location: Daikin Park (Houston)
📺 TV: ESPN
💻 Streaming: YouTube TV

❓Sunday Night Baseball FAQs

How do betting odds work?

The Mariners are the -140 moneyline betting favorite, so a bettor would have to wager $140 to profit $100 if Seattle wins. Conversely, Houston’s +120 odds mean a bettor would profit $120 on a $100 wager if the Astros win.

What channel is Sunday Night Baseball on?

Sunday Night Baseball airs on ESPN and can be streamed through YouTube TV.

Who’s playing Sunday Night baseball?

The Sunday Night Baseball matchup is between the X and Y.

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