Dodgers vs. Diamondbacks Prediction, Odds & Expert Picks: MLB Best Bets for Sept. 23
Shohei Ohtani will get the ball for the Los Angeles Dodgers when they face the Arizona Diamondbacks at 9:40 p.m. ET tonight from Chase Field. And my Dodgers vs. Diamondbacks prediction believes in Arizona’s lineup ahead of this matchup.
The Dodgers have dropped six of Ohtani's past seven starts, a trend that could continue on Tuesday against a Diamondbacks team making a late playoff push. Los Angeles is a -160 favorite, but my MLB picks indicate the value is clearly on Arizona ahead of this rivalry matchup.
⚾ Dodgers vs. Diamondbacks prediction
MLB expert picks odds subject to change.
- Moneyline pick: Diamondbacks ML (+140 via FanDuel) ⭐⭐⭐
- Run line pick: Diamondbacks +1.5 (-120 via Caesars) ⭐⭐⭐
- Over/Under pick: Over 9 (+100 via FanDuel) ⭐⭐⭐
📝 Dodgers vs. Diamondbacks preview & best bet
Track the latest MLB scores for line movement and matchup info.
⬆️ Diamondbacks Over 3.5 runs (-113) ⭐⭐⭐⭐
It was challenging to nail down my favorite Dodgers vs. Diamondbacks prediction due to Arizona's immense value. The club’s moneyline and run-line price tags were tempting, but the team total is the best option because it can still be achieved in a defeat without relying on the pitching to hold up its end.
The Diamondbacks have continued to boast one of the best offenses in the sport, ranking fourth in the majors while averaging 4.96 runs per game. They've been averaging 5.2 runs since August, which is when their late-season push for a playoff spot truly began.
Arizona’s average has dropped to 4.6 across 10 meetings against Los Angeles, but there's a chance the team gets to face more of the Dodgers' bullpen on Tuesday. Ohtani hasn’t pitched more than five innings in a start, meaning the Dodgers will need to get the final 12-plus outs with a group of relievers that rank 20th in ERA.
I’ll back Arizona’s lineup on Tuesday at this -113 offering from FanDuel, as the rest of our best sports betting sites are sitting as high as -130.
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💰 Best Dodgers vs. Diamondbacks player prop bet
Our MLB player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬆️ Geraldo Perdomo Over 1.5 hits, runs, and RBIs (-105) ⭐⭐⭐⭐
The Diamondbacks boast several hitters worth a wager, but I like this -105 discount at DraftKings to back Geraldo Perdomo. He's accumulated the best WAR on the team (6.8).
Perdomo has cleared this line in nine of his past 11 outings, which includes two straight wins over the Philadelphia Phillies. I project value on this Over at -115 or better, but the current betting odds provide a $9.52 profit on a $10 bet for my favorite Dodgers vs. Diamondbacks player prop.
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📊 Dodgers vs. Diamondbacks odds: Sept. 23
MLB odds update live in real time.
📈 Dodgers vs. Diamondbacks betting odds analysis
The Dodgers opened as -160 favorites, and we’ve seen some slight movement in their favor with 57% of the wagers coming in on the visitors. The total has remained at a flat nine, though 56% of bets are on the Under.
Given the Dodgers’ popularity, particularly during Ohtani starts, I’m guessing the odds will continue to shift toward them. I also expect the Over to climb a tick before first pitch.
🔢 Dodgers vs. Diamondbacks stats
Season stats courtesy of baseball-reference.com.
| Dodgers | Statistic (per game) | Diamondbacks |
| 5.09 | Runs | 4.96 |
| 8.6 | Hits | 8.5 |
| .254 | AVG | .252 |
| .440 | SLG | .435 |
| .769 | OPS | .760 |
| 4.02 | ERA | 4.43 |
| 9.3 | K/9 | 8.0 |
| 3.5 | BB/9 | 3.1 |
| 1.1 | HR/9 | 1.2 |
🚑 Dodgers vs. Diamondbacks injury report
📺 Dodgers vs. Diamondbacks game info
- When: Tuesday, Sept. 23
- First pitch: 9:40 p.m. ET
- Where: Chase Field (Phoenix, AZ)
- How to watch: Local TV
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❓ Dodgers vs. Diamondbacks FAQs
Who is favored to win Dodgers vs. Diamondbacks?
The Dodgers are -160 favorites to defeat the Diamondbacks, giving them an implied probability of 61.54%.
What is the run line for Dodgers vs. Diamondbacks?
Los Angeles is a -1.5 run line favorite against Arizona on Tuesday. They're getting +105 to cover that while Arizona is receiving -120 to cover +1.5.
What is the Over/Under for Dodgers vs. Diamondbacks?
The total for Tuesday’s Dodgers-Diamondbacks matchup is nine, with the Over getting -105 and the Under at -114.
What are the best bets for Dodgers vs. Diamondbacks?
My best bets for Dodgers vs. Diamondbacks are Arizona’s team total (3.5) and Geraldo Perdomo Over 1.5 hits, runs, and RBIs.
When is the Dodgers vs. Diamondbacks game?
The Dodgers vs. Diamondbacks game is scheduled to begin at 9:40 p.m. ET on Tuesday.
How do baseball odds work?
When betting on MLB, the run line shows how many runs the favorite needs to win by in order to cash the bet. For example, a favorite of -1.5 must win by two or more runs to cover the run line, while an underdog at +1.5 must win outright or lose by one run to cover the run line.
Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total of runs will be higher or lower than the set number.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
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