Best Strikeout Props Today: MLB Expert Picks & Best Bets for Tuesday, July 21
Last Updated: July 21, 2026 3:37 PM EDT • 2 minute read X Social Google News Link
Welcome back to our best strikeout props today for Tuesday, July 21, after sweeping the slate twice last week. We might just be the best strikeout props on the internet right now.
Who's generating some whiffs (or lack thereof) for us on Tuesday? We're locking in Reynaldo Lopez and Framber Valdez to get the job done and win us a couple of bets. Let's dive into my best strikeout picks and predictions using odds from the top sports betting sites.
⚾ Best strikeout props today: Tuesday, July 21
See all of our experts’ MLB picks based on the latest MLB odds. Odds via FanDuel.
| ⚾ Strikeout pick | 💵 Units | 📝 Notes |
|---|---|---|
| Reynaldo Lopez Under 4.5 strikeouts (-150) | 2u → 1.33u | Lopez owns 16% K rate vs. Padres |
| Framber Valdez Over 4.5 strikeouts (-115) | 1u -> .87u | Valdez owns 34% K rate vs. Cubs |
Total wagered: 3 units | Max profit: 2.20 units
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💪 Best MLB strikeout predictions today
Here's a breakdown of my best MLB strikeout prop predictions and expert picks today. Check out the rest of our MLB picks along with our guide on how to bet on MLB.
Reynaldo Lopez Under 4.5 strikeouts vs. Padres (-150)
Lopez isn't getting hitters to whiff or chase, which is a recipe for disaster when it comes to strikeout props ... unless you're on the Under. The Braves righty has one of the lowest K rates of his career this year, and it doesn't get any better in this specific matchup. San Diego is striking out at just a 16% rate against Lopez, owning a .309 xBA across 74 plate appearances against him. With that type of sample size, I'm not seeing Lopez pitching deep into the game tonight.
Framber Valdez Over 4.5 strikeouts vs. Cubs (-115)
While Valdez is also striking hitters out at a career-low rate this season, he absolutely loves to see the Cubs on the schedule. Across 35 at-bats against him, Valdez is punching out this Cubs lineup at a 34% rate while limiting them to a .235 xBA, giving me the confidence he'll get at least six innings in the books tonight. Seiya Suzuki (0-for-5, 2Ks), Ian Happ (0-for-5, 3 Ks), and Pete Crow-Armstrong (0-for-3, 1 K) will all be in tough tonight. Let's sweep the board one more time, shall we?
🤑 More MLB player props today
Looking for more plays? Dive into Sean Tomlinson's best home run predictions today or my best NRFI bets today.
🎟️ Most-bet MLB player props today
Betting insights via BetMGM.
| Player | Team | Bet | Odds |
|---|---|---|---|
| Jac Caglianone | Royals | To hit 1+ home runs | +325 |
| Ian Happ | Cubs | To hit 1+ home runs | +675 |
| Shea Langeliers | A's | To hit 1+ home runs | +340 |
| Kyle Stowers | Marlins | To record 1+ total runs | +105 |
| Matt Vierling | Tigers | To hit 1+ home runs | +850 |
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