Best Home Run Predictions Today: MLB Odds, Picks & Prop Bets for Sept. 17

My bets home run predictions today focus on Corbin Carroll, Agustin Ramirez, Ben Rice, and Juan Soto.

Mike Spector

Last Updated: September 17, 2025 6:23 AM EDT • 4 minute read

Home Run Predictions Today: Best MLB Odds, Picks & Prop Bets for Sept. 17 — Pictured: Liam Hicks greets catcher Agustin Ramirez at the plate. Photo by Rhona Wise via Imagn Images

The four teams we selected yesterday hit eight home runs, and after none of the four players we picked cashed in on that barrage, positive regression says we should be profitable with our best home run predictions today.

Today’s MLB picks focus on New York Mets slugger Juan Soto, who faces a San Diego Padres starting pitcher who has struggled to keep the ball in the ballpark against the team from Queens. My best home run bets today also take fliers on Corbin Carroll, Agustin Ramirez, and Ben Rice at potential juicy payouts.

💰 MLB best home run predictions & odds today: Sept. 17

Best home run predictions today based on the latest MLB odds.

Corbin Carroll to hit a home run (+447 via DraftKings) ⭐⭐⭐
Juan Soto to hit a home run (+314 via DraftKings) ⭐⭐⭐⭐
Ben Rice to hit a home run (+400 via FanDuel) ⭐⭐
Agustin Ramirez to hit a home run (+400 via FanDuel) ⭐⭐

💣 Best home run prediction today: MLB expert picks & prop bets

Here is my favorite MLB home run bet today and analysis of why it leads my MLB home run predictions.

⚾ Juan Soto (Mets) to hit a home run ⭐⭐⭐

The Mets will be relying heavily on Soto down the stretch, as the team looks to hold onto one of the NL wild card spots and avoid missing the playoffs.

Soto and the Mets get a good matchup against Padres righty Nick Pivetta, who has allowed six home runs and a .968 OPS in 88 combined at-bats against current Mets hitters.

He is one of three Mets hitters who own an OPS of .944 or better against Pivetta with a minimum of 10 career at-bats. Two of his four career hits against Pivetta have gone for extra bases, including one home run.

The righty has allowed a home run in four of his last five starts and six of his previous eight.

Soto is one of three players in MLB history with 40-plus home runs, 30-plus stolen bases, and at least 115 walks in a single season, which he accomplished in his first season with the Mets.

The lefty slugger has homered in two of the last six games. After his team combined to hit four home runs yesterday, his 24.15% implied probability to homer becomes a great value play based on DraftKings’ +314 odds. That is where I am headed for the best payout, where a $10 winning wager would net $34.10 in profits.

📊 Padres vs. Mets odds

🚀 Best home run parlay picks

Use our parlay calculator to get the best odds for any parlay.

Corbin Carroll to hit a home run (+390 via FanDuel)
Juan Soto to hit a home run (+310 via FanDuel)
Ben Rice to hit a home run (+400 via FanDuel)
Agustin Ramirez to hit a home run (+400 via FanDuel)

Parlay odds: +50125 via FanDuel ($10 to win $5,012.50)

❓ Best home run predictions FAQs

What are the best home run props for tonight?

My best home run predictions today feature Corbin Carroll, Agustin Ramirez, Ben Rice, and Juan Soto.

What is a home run bet?

A home run bet is a wager on a hitter to hit a HR at any point during a game. Some sportsbooks allow you to bet on a hitter to not hit a home run, but the most common bet is on them to do so.

Can you parlay home run bets?

Yes, you can parlay home run bets. We've provided our best home run parlay today.

How do I place a home run bet?

To place a home run bet, simply go to your favorite sportsbook and go to the game featuring the player of your choice. Then click on batter props and you should see an option to bet a player to hit a home run.

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Written by:
Mike Spector

Mike started in the sports writing industry in July 2019, and gained a lot of followers in his first year after finishing with the No. 2 overall record in an annual NFL betting competition, which made picks against the spread, and from an Over/Under and moneyline perspective. Mike is an avid fan of the NFL, MLB, tennis, and all college sports. In his opinion, March Madness is the best sporting event there is, and he's especially euphoric starting with conference tournament time in college basketball. Mike's a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." When making wagers, Mike leans on his NFL experience and always scours the best odds at all of the major sports betting sites, where he mostly sifts through DraftKings, FanDuel, BetMGM, and bet365. He's tried several others and is of the firm belief that bettors should not just stick to one sportsbook, as there is always likely better value to be had with the same wager. In addition, while Mike received his undergraduate degree from Villanova University, he has no issue betting against the Wildcats when it comes to college basketball wagering, and suggests other bettors should always put their “head” before their “hearts.”