Syracuse vs. Wake Forest Picks, Predictions College Football Week 12: Who Will End Losing Streak?

Top college football picks for the Week 12 ACC matchup between Syracuse and Wake Forest.

Philip Wood

Last updated: November 17, 2022 7:54 AM EST • 3 min read

Two 6-4 ACC teams go head-to-head Saturday when Syracuse meets Wake Forest. What Syracuse-Wake Forest picks offer the best value when the two teams meet in Week 12?

It’s been a tale of two seasons for the Syracuse Orange. They got off to a 6-0 start and earned bowl eligibility for the first time since 2018, but they have lost four in a row since.

The Wake Forest Demon Deacons’ season has followed a similar trajectory. They started 6-1 with their only loss to Clemson, but they have lost three in a row to drop to 6-4.

Here are our top picks for Syracuse-Wake Forest (odds via FanDuel Sportsbook, DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).

Syracuse vs. Wake Forest Picks

Syracuse vs. Wake Forest ATS Pick

Wake Forest -9.5 (-114) ★★★

It’s hard to trust the Demon Deacons to win by more than 10, but it’s even harder to trust this Syracuse offense to do anything. The Orange have scored 12 points in their last two games and they haven’t found the end zone since their Oct. 29 loss to Notre Dame.

Last week, Garrett Shrader took the Syracuse starting quarterback role back from Carlos Del Rio-Wilson, but he managed just 65 yards through the air. The Demon Deacons have lost to quality opponents, while the Orange are just completely lost.

Syracuse vs. Wake Forest O/U Pick

Under 56 (-110) ★★★

Is the Orange’s offensive funk temporary? In their last two games, they have combined for 305 total yards of offense. Prior to those two games, they had scored 21 or more points in every single game.

The Demon Deacons have given up 30 or more points in three consecutive. However, until Syracuse’s offense shows some life, the Orange aren’t going to be able to take advantage of any defense. The Demon Deacons will score at least 21 like they have done in every game this season, but that won’t be enough to push this Over.

Syracuse vs. Wake Forest Prop Pick

Wake Forest 1st Half -5.5 (-110) ★★★

The Demon Deacons have trailed at the half of two of their last three games. Yet, in their two most recent wins over Boston College and Army, they led by double digits at the break in both games.

The Orange have trailed at halftime of their last three games, including by 21 last week against Florida State. The Demon Deacons haven’t been perfect of late, but they can score, which is not something that can be said of Syracuse.

Where to Bet on Syracuse vs. Wake Forest

Here are our top-rated sportsbooks:

Syracuse-Wake Forest picks made 11/17/2022 at 10:36 a.m. ET

Written By:
Philip Wood

Phil has covered sports betting since 2016, and he has been with SportsBook Review since 2022. He previously hosted the College Football Pick 'Em podcast for CanesInsight.com. He is always looking for value, especially on lines that just seem too good to be true. His belief is that if a line doesn't make sense just assume oddsmakers know something you don't. He also loves in-season futures. There is so much value to be had as the public overreacts weekly. Bettors tend to forget just how long NFL and college football seasons are. After all, the Green Bay Packers were 2-5 in 2023 and they made it to the Divisional Round. When deciding where to bet, it comes down to value over everything. +100 is always better than -110. An alumnus of The U, Phil always holds out hope that the next head coach will be the one who turns the football program around. He is also a diehard Detroit Lions fan and is willing to forgive Dan Campbell for forgetting that a kicker can be useful.