South Carolina vs. LSU Prediction, Picks & Odds: College Football Week 7

My best South Carolina vs. LSU prediction focuses on LSU’s early-season struggles ahead of Saturday’s game at Tiger Stadium in Baton Rouge, La. No. 11 LSU is favored a 9-point betting favorite ahead of kickoff at 7:45 p.m. ET (SEC Network).

While the majority of college football picks against the spread back LSU to cover, I think that South Carolina’s brand of mistake-free football gives them a clear advantage over Garrett Nussmeier and Co. My college football predictions for Week 7 expect that advantage to extend to limiting Nussmeier's passing touchdowns.

🏈 South Carolina vs. LSU predictions

College football expert picks for Week 7; odds subject to change.

• Game prediction: South Carolina +9 (-110 via Caesars) ⭐⭐⭐⭐⭐
• Over/Under pick: Under 44.5 (-110 via BetMGM) ⭐⭐⭐⭐
• Player prop bet: Garrett Nussmeier Under 1.5 passing touchdowns (+104 via FanDuel) ⭐⭐⭐⭐

🆚 Who will win South Carolina vs. LSU?

LSU is 2-1 against power conference teams, but they’ve been outgained in two of those three contests. Two weeks ago, against Ole Miss, they were outgained 480-254, and they trailed by multiple scores with just over five minutes left.

The only time South Carolina hasn’t been competitive this year was when starting quarterback LaNorris Sellers got hurt against Vanderbilt. LSU relies on turnovers to succeed, but South Carolina has just four turnovers all season. If Sellers and his teammates take care of the ball, South Carolina will win this game.

Prediction: South Carolina 21, LSU 17

✅ South Carolina vs. LSU expert pick

Track the latest college football scores for line movement and matchup info.

🐓  South Carolina +9 (-110) ⭐⭐⭐⭐⭐

Taking South Carolina’s moneyline of +275 at BetMGM is a solid play, but taking South Carolina to cover 9 for -110 at Caesars is possibly the best play of the weekend. In three games against power conference teams, LSU has won just one game by more than nine. That came by defeating Florida 20-10, a game in which the defense forced five turnovers.

Sellers has just one interception this year, as three of South Carolina’s four turnovers have come without him on the field. If he takes care of the football, then the South Carolina defense, which has held three opponents to 13 or fewer, should be able to keep LSU’s 81st-ranked scoring offense in check.

The price of -110 implies a 52.38% chance that South Carolina covers. A $10 bet would pay $9.09.

💰 Best South Carolina vs. LSU player prop bet

Our college football player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

⬇️  Garrett Nussmeier Under 1.5 passing touchdowns (+104) ⭐⭐⭐⭐

LSU quarterback Garrett Nussmeier has thrown just one touchdown pass in four of his five games this season. The only time he threw more than one was when he tossed three against SE Louisiana. That was also the only game where LSU scored more than 23 points.

South Carolina is allowing just 0.8 passing touchdowns per game. The only time they let a quarterback throw more than one passing touchdown was when Vanderbilt QB Diego Pavia threw two, and South Carolina turned the ball over four times in that game.

The price for the Under is +104 at FanDuel, meaning a $10 bet would pay $10.40. The price easily makes this the most valuable South Carolina vs. LSU prediction. The odds imply a 49.02% chance that Nussmeier does something he’s done just once in five games.

📊 South Carolina vs. LSU odds

Latest college football odds updated live in real time.

📺 How to watch South Carolina vs. LSU: Week 7

• Date: Saturday, Oct. 11
• Kickoff: 7:45 p.m. ET
• Where: Tiger Stadium (Baton Rouge, La.)
• TV: SEC Network