College Football Predictions Week 11: Best Bets & Odds for Top Matchups

Check out the latest college football predictions and odds for Week 11, including our best bets and expert picks for all the top matchups.
Texas Tech tight end Terrance Carter Jr. (7) runs with the ball against Kansas State, and the Red Raiders' matchup with BYU on Saturday is among our top college football predictions for Week 11.
Pictured: Texas Tech tight end Terrance Carter Jr. (7) runs with the ball against Kansas State, and the Red Raiders' matchup with BYU on Saturday is among our top college football predictions for Week 11. Photo by Scott Sewell via Imagn Images.

Coming off a Saturday slate that saw five teams ranked in the top 20 lose, our college football Week 11 predictions cover the can't-miss matchups this week that will have the biggest impact on conference championship races and the College Football Playoff rankings.

This week, our college football picks cover the College GameDay matchup between BYU and Texas Tech, Oregon's toughest game since losing to Indiana, a ranked SEC matchup, LSU's first game after firing Brian Kelly, and much more.


🏈 College football predictions: Week 11

Here are all of our college football expert picks for Week 11, which we'll update throughout the week.

  • UMass vs. Akron prediction (coming soon)
  • Miami (OH) vs. Ohio prediction (coming soon)
  • Kent State vs. Ball State prediction (coming soon)
  • Northern Illinois vs. Toledo prediction (coming soon)
  • Georgia Southern vs. Appalachian State prediction (coming soon)
  • UTSA vs. South Florida prediction (coming soon)
    • UTSA vs. South Florida player props (coming soon)
  • Houston vs. UCF prediction (coming soon)
  • Northwestern vs. USC prediction (coming soon)
    • Northwestern vs. USC player props (coming soon)
  • Tulane vs. Memphis prediction (coming soon)
    • Tulane vs. Memphis player props (coming soon)
  • BYU vs. Texas Tech prediction (coming soon)
  • Indiana vs. Penn State prediction (coming soon)
  • Oregon vs. Iowa prediction (coming soon)
  • Early Texas A&M vs. Missouri prediction (coming soon)
    • Texas A&M vs. Missouri prediction (coming soon)
    • Texas A&M vs. Missouri player props (coming soon)
  • Syracuse vs. Miami player props (coming soon)
  • Diego Pavia player prop bets (coming soon)
  • Early LSU vs. Alabama prediction (coming soon)
    • LSU vs. Alabama prediction (coming soon)
    • LSU vs. Alabama player props (coming soon)
    • LSU vs. Alabama anytime touchdown scorer predictions (coming soon)
  • Early Navy vs. Notre Dame prediction (coming soon)
    • Navy vs. Notre Dame prediction (coming soon)

🌐 Want more trusted analysis?

Add Sportsbook Review as one of your "source preferences" to see more of our expert picks and predictions in your Google search results and Discover feed.


💰 College football odds & expert picks: Tuesday

Here are the latest college football odds for every Week 11 game via the best college football betting sites, which update live in real time. 

📊 UMass vs. Akron odds

  • Date: Tuesday, Nov. 4
  • Kickoff: 7 p.m. ET
  • Location: InfoCision Stadium (Akron, Ohio)
  • How to watch: CBSSN

📊 Miami (OH) vs. Ohio odds

  • Date: Tuesday, Nov. 4
  • Kickoff: 7 p.m. ET
  • Location: Peden Stadium (Athens, Ohio)
  • How to watch: ESPN2

💰 College football odds & expert picks: Wednesday

📊 Kent State vs. Ball State odds

  • Date: Wednesday, Nov. 5
  • Kickoff: 7 p.m. ET
  • Location: Scheumann Stadium (Muncie, Ind.)
  • How to watch: ESPNU

📊 Northern Illinois vs. Toledo odds

  • Date: Wednesday, Nov. 5
  • Kickoff: 7 p.m. ET
  • Location: Glass Bowl (Toledo, Ohio)
  • How to watch: ESPN2

💰 College football odds & expert picks: Thursday

📊 Georgia Southern vs. Appalachian State odds

  • Date: Thursday, Nov. 6
  • Kickoff: 7:30 p.m. ET
  • Location: Kidd Brewer Stadium (Boone, N.C.)
  • How to watch: ESPN2

📊 UTSA vs. South Florida odds

  • Date: Thursday, Nov. 6
  • Kickoff: 7:30 p.m. ET
  • Location: Raymond James Stadium (Tampa, Fla.)
  • How to watch: ESPN

💰 College football odds & expert picks: Friday

📊 Houston vs. UCF odds

  • Date: Friday, Nov. 7
  • Kickoff: 8 p.m. ET
  • Location: FBC Mortgage Stadium (Orlando, Fla.)
  • How to watch: FS1

📊 Northwestern vs. USC odds

  • Date: Friday, Nov. 7
  • Kickoff: 9 p.m. ET
  • Location: Los Angeles Memorial Stadium (Los Angeles)
  • How to watch: FOX

📊 Tulane vs. Memphis odds

  • Date: Friday, Nov. 7
  • Kickoff: 9 p.m. ET
  • Location: Simmons Bank Liberty Stadium (Memphis, Tenn.)
  • How to watch: ESPN

💰 College football odds & expert picks: Saturday

📊 BYU vs. Texas Tech odds

  • Date: Saturday, Nov. 8
  • Kickoff: Noon ET
  • Location: Joes AT&T Stadium (Lubbock, Texas)
  • How to watch: ABC

🔮 BYU vs. Texas Tech early prediction

⬇️ Under 53.5 (-110)

The winner of this game will potentially punch its ticket to the Big 12 Championship, and while Texas Tech is coming off a blowout win against Kansas State, the Red Raiders' offense was sporadic for three quarters. BYU's defense should challenge Behren Morton and Co., while Texas Tech's defense will create plenty of problems for Cougars freshman QB Bear Bachmeier. With players like Jack Kelly and Faletau Satuala taking the field for BYU's defense and defenders like David Bailey and Jacob Rodriguez leading Texas Tech's, points will be scarce. 

📊 Indiana vs. Penn State odds

  • Date: Saturday, Nov. 8
  • Kickoff: Noon ET
  • Location: Beaver Stadium (University Park, Pa.)
  • How to watch: FOX

📊 Oregon vs. Iowa odds

  • Date: Saturday, Nov. 8
  • Kickoff: 3:30 p.m. ET
  • Location: Kinnick Stadium (Iowa City, Iowa)
  • How to watch: CBS

🔮 Oregon vs. Iowa early prediction

🐤 Iowa +6.5 (-110)

This is a classic Iowa trap game, with the Hawkeyes having an offense that leaves plenty to be desired and a defense that's ranked No. 6 by SP+. With Oregon looking a little iffy at home against Wisconsin two weeks ago, and Dante Moore exiting the game with a nose injury, the Ducks could be sluggish in this cross-country game at one of the toughest stadiums to play at in the Big Ten. Look for Iowa to muck this game up and lean on QB Mark Gronowski's rugged running style to make enough plays on offense to keep this close.


📊 Texas A&M vs. Missouri odds

  • Date: Saturday, Nov. 8
  • Kickoff: 3:30 p.m. ET
  • Location: Memorial Stadium (Columbia, Mo.)
  • How to watch: ABC

🔮 Texas A&M vs. Missouri early prediction

🐯 Missouri +6.5 (-114)

Without a doubt, Texas A&M has been the most consistent program in the SEC this season behind an underrated defense and a dynamic offense led by Marcel Reed. However, the Aggies haven't played a truly high quality opponent since Notre Dame in mid-September. Though Missouri has two losses, it played both Alabama and Vanderbilt close as an underdog and it has the talent in the trenches to keep things tight with Texas A&M. Coming off a bye week, Eli Drinkwitz should have Matt Zollers prepared to start at QB, and it doesn't hurt having an elite running back like Ahmad Hardy.


📊 Syracuse vs. Miami odds

  • Date: Saturday, Nov. 8
  • Kickoff: 3:30 p.m. ET
  • Location: Hard Rock Stadium (Miami)
  • How to watch: ESPN

📊 Auburn vs. Vanderbilt odds

  • Date: Saturday, Nov. 8
  • Kickoff: 4 p.m. ET
  • Location: FirstBank Stadium (Nashville)
  • How to watch: SEC Network

📊 LSU vs. Alabama odds

  • Date: Saturday, Nov. 8
  • Kickoff: 7:30 p.m. ET
  • Location: Bryant-Denny Stadium (Tuscaloosa, Ala.)
  • How to watch: ABC

🔮 LSU vs. Alabama early prediction

🐘 Alabama -10.5 (-110)

Brian Kelly is gone, and renowned recruiter Frank Wilson is LSU's interim head coach, but Wilson can't fix the problems plaguing the Tigers' program. There are a million reasons why LSU is in rough shape heading into this matchup, and one of them is the distractions being caused by Gov. Jeff Landry. Meanwhile, Alabama is sitting pretty with Ty Simpson playing at a Heisman-level and the Tide's defense holding every SEC opponent it's faced to 24 points or fewer. These teams are trending in entirely different directions, and the Tide should roll the Tigers.


📊 Navy vs. Notre Dame odds

  • Date: Saturday, Nov. 8
  • Kickoff: 7:30 p.m. ET
  • Location: Notre Dame Stadium (Notre Dame, Ind.)
  • How to watch: NBC, Peacock

💡 College football expert picks: Week 11

  • College football picks against the spread Week 11 (coming soon)
  • MAC best bets Week 11 (coming soon)
  • College football predictions for every top 25 game in Week 11 (coming soon)
  • College football player props Week 11 (coming soon)
  • Big Ten best bets Week 11 (coming soon)
  • SEC best bets Week 11 (coming soon)
  • College football Week 11 betting report (coming soon)
  • College football anytime touchdown scorer predictions Week 11 (coming soon)
  • Heisman Trophy power rankings Week 11 (coming soon)
  • College football best bets Week 11 (coming soon)

📃 Affiliate disclosure

Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)