College Football Moneyline Parlay Picks Week 5: Best Parlay Bets for $171.10 Payout

We whiffed last week - Clemson and Cal are officially banned from future editions of our college football moneyline parlay picks, because what in the world was that, boys? Still, it wasn’t nearly as bad as what Illinois put on tape against Indiana.

For our college football predictions for Week 5, we’re taking several small favorites in marquee games to juice our parlay odds up to +1711 on a 10-leg moneyline parlay.

If you’re looking for a Saturday sweat that we’re hoping lasts all day long, check out my 10 favorite college football picks below.

🏈 College football moneyline parlay picks: Week 5

College football parlay picks for Week 5; odds subject to change.

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💰 Best college football moneyline picks to parlay

Here are my favorite moneyline picks and best bets for Week 5 based on the best college football odds for the full parlay.

🚀 Kansas (-189) ⭐⭐⭐⭐⭐

Kansas held a conference opponent to 10 or fewer points for the first time since 2007 in last week’s win over West Virginia, and this is a Jayhawks team still driven by the dynamic QB Jalon Daniels.

Lance Leipold can say Cincinnati is the best team KU will have faced all he wants, but the reality is the Bearcats lost on a neutral field to Nebraska and didn’t come close to covering the number against Bowling Green.

Statistically, Cincy is middling on both sides of the ball and won’t hold up in its first road test of the season.

🚀 Indiana (-305) ⭐⭐⭐⭐⭐

I had evidently identified the wrong team as fraudulent in last week’s matchup between Illinois and Indiana. Fernando Mendoza leads the latest Heisman Trophy odds and should guide the Hoosiers to a road win.

Sure, Iowa is known for its defense, which has allowed a respectable 252.3 yards per game. But if Rutgers can pin 28 points on Iowa, this isn’t the same Iowa defense we’re used to seeing. A rare road team in our parlay, Indiana can pour it on in any venue.

Iowa’s offense ranks 95th in yards per game and won’t be able to keep pace with Mendoza and the Hoosiers, who average 559.0 yards per game (third in FBS).

🚀 South Carolina (-200) ⭐⭐⭐⭐⭐

South Carolina has fallen on hard times with SEC losses to Vanderbilt and Missouri over the past two weeks, but this is a get-right spot for a team that is still more talented than recent performances would suggest.

LaNorris Sellers threw for over 300 yards at Missouri but was let down by his defense, which was gashed on the ground. Kentucky also has a solid rushing offense, but the Gamecocks have athletes on defense to keep the Wildcats in check.

This is the type of loss that lands coaches on hot seats, and I don’t see Shane Beamer getting into the danger zone at home.

💰 Best Week 5 parlay odds

Our parlay calculator shows the best odds for every market across legal sportsbooks in your area.