College Football Week 10 Betting Report: Most Bet Games, Spreads & Public Picks

We break down the college football Week 10 betting report while looking at the most-bet games, spreads, and where the public money is landing.
Texas head coach Steve Sarkisian reacts after beating Mississippi State, and the Longhorns' matchup with Vanderbilt this week is among the games our college football Week 10 betting report highlights.
Pictured: Texas head coach Steve Sarkisian reacts after beating Mississippi State, and the Longhorns' matchup with Vanderbilt this week is among the games our college football Week 10 betting report highlights. Photo by Petre Thomas via Imagn Images.

There are several marquee matchups this week, and our college football Week 10 betting report highlights the most bet games by the public, from Penn State vs. Ohio State's Big Noon Kickoff game to Cincinnati vs. Utah's College GameDay matchup after dark.

To help with your college football predictions for Week 10, our betting report shows you what the public is on, from spreads to Over/Unders to player props for this week's slate of games.


📊 College football Week 10 betting report and trends

College football betting insights via BetMGM.

🎮 Most bet games and odds movement

Game Opening/current spread Opening/current total Opening/current ML
Vanderbilt vs. Texas Texas -2.5/Texas -3 45.5/46.5 Texas -120/Texas -155
Penn State vs. Ohio State Ohio State -20.5/Ohio State -19.5 44.5/44.5 Ohio State -1650/Ohio State -1400
Oklahoma vs. Tennessee Tennessee -4/Tennessee -2.5 56.5/55.5 Tennessee -165/Tennessee -135
Memphis vs. Rice Memphis -14.5/Memphis -14 51.5/48.5 Memphis -600/Memphis -600
Georgia vs. Florida Georgia -7.5/Georgia -7.5 50.5/50.5 Georgia -300/Georgia -275

💰️ Penn State vs. Ohio State prediction: Ohio State -20.5

Ohio State is allowing just 85.6 rushing yards per game. Without a threatening passing attack from the Nittany Lions, Ohio State will sell out to stop the run, and the Penn State running backs will get no room to maneuver.

- via Philip Wood's Penn State vs. Ohio State prediction

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↔️ Most bet spreads

Team Oppenent Bet percentage Handle percentage
Ohio State -19.5 vs. Penn State 69% 85%
Tennessee -2.5 vs. Oklahoma 74% 68%
Texas -2.5 vs. Vanderbilt 52% 75%
Rice +14 vs. Memphis 53% 44%
Cincinnati +10 vs. Utah 73% 60%

💰️ Cincinnati vs. Utah: Cincinnati +10.5

A long day of tailgating for what should be a fun one between a Utah program that followed up its loss in the Holy War by stomping Colorado, and a Cincinnati team that's been a massive overachiever. While the Utes' defense and run game are among the best in the Big 12, Cincinnati is littered with NFL talent. Look for Brendan Sorsby, Joe Royer, Cyrus Allen, and Jake Golday to bring their best in front of NFL scouts.

- via Rob Paul's college football predictions for every top 25 game in Week 10


⚖️ Most bet totals

Game Over/Under Bet percentage Handle percentage
Penn State vs. Ohio State Over 44.5 85% 96%
Vanderbilt vs. Texas Under 46.5 70% 79%
Memphis vs. Rice Over 48.5 74% 76%
Indiana vs. Maryland Over 50.5 88% 85%
Oklahoma vs. Tennessee Over 52.5 66% 36%

💰️ Vanderbilt vs. Texas prediction: Under 46.5

 The Longhorns' defense ranks in the top 10 in pass rush, passing downs EPA allowed, and tackling grade (per PFF). While Vanderbilt’s offense does rank in the top 10 in quality drives and finishing drives, there will be much tougher sledding to move the ball solely on the ground if Texas limits its passing attack.

- via Mike Spector's college football best bets for Week 10


🐶 Most bet underdogs to win

Underdog Opponent Bet percentage Handle percentage
Vanderbilt +130 vs. Texas 71% 16%
Penn State +825 vs. Ohio State 65% 10%
Cincinnati +300 vs. Utah 86% 87%
Oklahoma +110 vs. Tennessee 52% 48%
Rice +425 vs. Memphis 47% 53%

💰️ Oklahoma vs. Tennessee prediction: Oklahoma +3.5

The Volunteers' offense is impressive on paper (No. 2 in SP+). But in its only matchup against a top-15 defense by SP+ this year (Alabama at No. 12), Josh Heupel's program managed just 20 points, and Joey Aguilar produced a season-low QBR (60.0). Brent Venables' Oklahoma defense is ranked No. 4 by SP+ and No. 5 in EPA per pass, thanks to a terrifying pass rush that R Mason Thomas leads. 

- via Rob Paul's college football picks against the spread for Week 10


🎯 Most bet player props

Player Player prop Matchup
Malachi Toney, WR, Miami Over 64.5 receiving yards (-115) vs. SMU
Bo Jackson, RB, Ohio State Over 50.5 rushing yards (-115) vs. Penn State
Joe Jackson, RB, Kansas State Under 71.5 rushing yards (-115) vs. Texas Tech
Avery Johnson, QB, Kansas State Under 37.5 rushing yards (-115) vs. Kansas State
John Mateer, QB, Oklahoma Under 254.5 passing yards (-115) vs. Tennessee

💰️ Our favorite player prop: Avery Johnson Under 37.5 rushing yards

Texas Tech ranks No. 2 in the nation in EPA per rush and allows the fewest rushing yards per game in the country (68.1). And it doesn't help Johnson's chances with sacks counting against rushing yards in college. The Red Raiders are No. 9 in the country in sacks (26) thanks to David Bailey and Romello Height.

- via Rob Paul's college football player props Week 10


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