Best LSU vs. Clemson Player Prop Bets Tonight: College Football Week 1 Odds & Expert Picks

My best LSU vs. Clemson player props to our college football predictions for Week 1 have plenty to choose from as two of the best quarterbacks in the country, Garrett Nussmeier and Cade Klubnik, battle in a clash in AP top 10 ranked teams.

Clemson is favored by between 3.5 and 4.5 points ahead of tonight's 7:30 p.m. ET (ABC) kickoff at Memorial Stadium in Clemson, S.C. My college football picks anticipate key offensive players from both teams performing well.   

For more information, we offer a full breakdown of this matchup along with the latest live odds in our LSU vs. Clemson prediction.

🏈 Best LSU vs. Clemson player props: Week 1

College football player prop bets made Friday; odds subject to change.

• Antonio Williams anytime TD scorer (+110 via Caesars) ⭐⭐⭐⭐
• Bryant Wesco Jr. Over 56.5 receiving yards (-115 via bet365) ⭐⭐⭐⭐
• Garrett Nussmeier Over 284.5 passing yards (-114 via FanDuel) ⭐⭐⭐⭐

💰 Best LSU vs. Clemson player prop bets

Our college football player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

🔥 Antonio Williams anytime touchdown scorer (+110) ⭐⭐⭐⭐

Betting $10 to win $11 on a player to score a touchdown usually isn’t great value. But in the case of Antonio Williams, this is one of the best prop bets for this game.

Williams scored 12 touchdowns last season, including at least one in nine of his 14 games. He even scored one in the College Football Playoff against a Texas defense that finished last season as the second-best scoring defense in the nation.

The price from Caesars suggests that Williams has a 47.62% chance of scoring in this game, and I think that’s undervaluing him. LSU gave up nearly 25 points per game in 2024-25 and struggled against the pass. In a solid matchup, I expect Clemson’s best receiver to find the end zone at least once.

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⬆️ Bryant Wesco Jr. Over 56.5 receiving yards (-115) ⭐⭐⭐⭐

Clemson returns all three of its leading receivers from a season ago. Bryant Wesco Jr. finished last season with the second-most yards and fourth-most receptions, but I like his potential in this game the most.

Wesco recorded at least 61 yards in four of his final five games. In all, he topped 56.5 yards in six of his 12 games. He is the Tigers’ best big-play threat after recording two touchdowns of 70 or more yards last season, and he begins this year against a defense that barely ranked in the top 75 in passing yards allowed in 2024-25.

Caesars is offering the total at 54.5, but the price for the Over is -125. The price from bet365 suggests a 53.49% chance that Wesco records more than 56.5 receiving yards, and a $10 bet pays $8.70, so I recommend wagering there.

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⬆️ Garrett Nussmeier Over 284.5 passing yards (-114) ⭐⭐⭐⭐

Though I like Cade Klubnik’s matchup better, Garrett Nussmeier proved last season that he can throw for a lot of yards against anyone. In 13 games, he managed at least 285 yards nine times, and he never threw for less than 233.

The Clemson pass defense ranked in the middle of the country last season, so if anyone is going to slow Nussmeier down, it’s unlikely to be the Tigers. That said, get in sooner rather than later, as I wouldn’t take this number much higher than where it is right now.

Of the four major best sports betting sites offering this prop, two have the Over set at 289.5. Both are asking -115 for the Over, which is a slightly worse price than the -114 FanDuel is asking for five fewer yards. The current price suggests a 53.27% chance this Over hits. A $10 bet would pay $8.77.

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📺 LSU vs. Clemson game info

• When: Saturday, Aug. 30
• Kickoff: 7:30 p.m. ET
• Where: Memorial Stadium, Clemson, S.C.
• How to watch: ABC

❓ LSU vs. Clemson FAQs

What are the best LSU vs. Clemson player props?

Baked on the latest college football odds, the best LSU vs. Clemson player props are Antonio Williams to score a touchdown, Garrett Nussmeier to throw for at least 285 yards, and Bryant Wesco Jr. to record at least 57 receiving yards.

When is the LSU vs. Clemson game?

LSU vs. Clemson kicks off at 7:30 p.m. ET on ABC. The game will be played at Memorial Stadium in Clemson, S.C.

How do college football player props work?

Player props are wagers on individual performances rather than the outcome of the game. Common props include passing yards, rushing yards, receiving yards, and touchdown scorers. For example, if a QB’s passing yards line is set at 250.5, you can bet the Over (251-plus yards) or Under (250 or fewer yards). You can also bet on if a specific player will score a touchdown in the entire game, the first or last touchdown, and more.

You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.

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