Florida State vs. Stanford Prediction Tonight: Expert Pick & Best Bets for College Football Week 8

Our Florida State vs. Stanford prediction and picks tonight expect the Seminoles to play inspired after losing three straight and to cover this 17.5-point spread (-112).
Pictured: Florida State Seminoles quarterback Thomas Castellanos (1) during the first half. Photo by Melina Myers-Imagn Images

My Florida State vs. Stanford prediction and picks tonight back the Seminoles to cover as a 17.5-point betting favorite after a three-game skid. 

My college football picks also include a play on the Over/Under due to recent trends. Kickoff from Stanford Stadium in Stanford, Calif., is set for 10:30 p.m. ET (ESPN) tonight. Our college football predictions for Week 8 feature plays for all the biggest games tonight, including the following side and total bets.


🏈 Florida State vs. Stanford prediction

College football picks for Week 8; odds subject to change.

  • Game prediction: Florida State -17.5 (-112 via DraftKings) ⭐⭐⭐⭐
  • Over/Under pick: Over 53 (-110 via Caesars) ⭐⭐⭐⭐

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🆚 Who will win Florida State vs. Stanford tonight?

Stanford is 1-2 in ACC play, losing its last two conference games by an average of 26 points. While Florida State has lost eight consecutive conference games dating back to last season, it has too much talent to lose to Stanford, even though this is a tricky West Coast road game with a late start time.


✅ Best Florida State vs. Stanford bet tonight

🪓 Florida State -17.5 (-112) ⭐⭐⭐⭐

I correctly predicted Pittsburgh over Florida State as one of my top three college football upset picks last week, with the reasoning largely being that I was buying low on Pitt’s offense led by its new freshman starting quarterback. But the Seminoles were outstanding on defense leading into that matchup against an unknown quarterback, and the issues the Panthers presented should not surface this week.

Seminoles' defense to bounce back

Florida State’s defense entered last week ranked eighth in EPA/rush and in the top 15 in available yards allowed and early-downs EPA allowed. The Seminoles’ third-down defense last week wasn’t exactly poor, holding Pitt to just 5-of-14 third-down conversions. But Florida State was undone by three fourth-down conversions that extended Panthers drives.

Stanford is 0-5 ATS in its last five October games, and its two outright wins this season came against San Jose State and Boston College teams that are a combined 3-9 SU. 

I am headed to DraftKings for the best price and number on Florida State’s point spread. Other best sports betting sites have already moved to -18, while DraftKings is the only one charging less than -115 juice at 53.49% implied odds to lay the points. Through its -112 odds, a $10 wager would net $8.93 in profits if Florida State covers the spread.


⚖️ Florida State vs. Stanford score prediction: Florida State 38 - Stanford 17

Track the latest college football scores for line movement and matchup info.

⬆️ Over 53 (-110) ⭐⭐⭐⭐

After a 3-1 start when its only loss was to Virginia, Florida State quarterback Tommy Castellanos had a 91.0 passing grade from PFF, which led all quarterbacks at the time. He relinquished that top spot after facing two tough opponents in Miami and Pittsburgh, but he should get right against a Stanford defense that is one of four in the conference to allow 181-plus points this year.

In the Cardinal’s last three games, Virginia, San Jose State, and SMU quarterbacks have combined for a 10-0 touchdown-to-interception ratio, while all three had a QBR of 75.1 or higher. Cavaliers quarterback Chandler Morris threw for three touchdowns in the first quarter alone against Stanford. 

This is a four-star Florida State vs. Stanford score prediction, as the Over is 7-1 in the Seminoles’ last eight October games as a favorite against unranked teams. The O/U is as high as 53.5 (juiced to -105 at 51.22% implied odds for the Over). Thus, the best number and price is at Caesars, where a $10 winning wager would return $9.09 in profits.


📊 Florida State vs. Stanford odds

Latest college football odds updated live in real time.


📺 How to watch Florida State vs. Stanford tonight

  • Date: Saturday, Oct. 18
  • Kickoff: 10:30 p.m. ET
  • Where: Stanford Stadium (Stanford, Calif.)
  • TV: ESPN

📈 College football betting insights

College football betting insights via BetMGM.

Most bet games Most bet Over/Unders Most bet underdogs to win
LSU vs. Vanderbilt Texas A&M vs. Arkansas (Under 58.5) LSU +115 vs. Vanderbilt
Ole Miss vs. Georgia Ole Miss vs. Georgia (Over 56.5) Georgia Tech +100 vs. Duke
USC vs. Notre Dame Ohio State vs. Wisconsin (Over 41.5) Tennessee +260 vs. Alabama

💡 College football expert picks: Week 8


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