USC vs. Notre Dame Prediction & Odds: Early Picks for College Football Week 8
In a clash of historic programs, my best USC vs. Notre Dame prediction and college football picks based on the opening odds focus on the Fighting Irish's defensive improvements over their last three games.
Despite Notre Dame being a 7.5- to 8.5-point betting favorite, I’m more interested in the total as part of my college football predictions for Week 8.
Saturday’s game kicks off at 7:30 p.m. ET (NBC, Peacock) from Notre Dame Stadium in Notre Dame, Ind.
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🏈 USC vs. Notre Dame prediction & best bet
Stay ahead with the rest of our early college football predictions for Week 8.
⬇️ Under 61.5 (-110) ⭐⭐⭐⭐
Notre Dame has held opponents to 13 points or fewer in its last three games. In Week 7, they held an NC State team that had scored at least 21 in all of its games to just seven points and 233 yards of offense.
USC is averaging 45.5 points per game, third-most in the nation. However, they’ve scored 32 or fewer in back-to-back games. Notre Dame is allowing just 20.8 points and 351.5 yards per game, despite facing two top-five teams. Additionally, Notre Dame is averaging 36.7 rushes and 172.7 rushing yards per game, so look for them to control the clock and keep USC out of its usual offensive rhythm.
All of our best college football betting sites have this total set at 61.5, and are offering -110 for the Under. The odds imply a 52.38% chance that the Under hits with a $10 bet paying a $9.09 profit.
📊 USC vs. Notre Dame odds: Week 8
Latest college football odds updated live in real time.
📈 USC vs. Notre Dame opening odds
- Moneyline: USC +240 | Notre Dame -300
- Spread: USC +7.5 (-105) | Notre Dame -7.5 (-115)
- Over/Under: Over 62.5 (-110) | Under 62.5 (-110)
💡 USC vs. Notre Dame odds analysis
With USC on the right side of the key number of 7, I expect the Trojans to see a lot of love early. Look for bettors to focus more on USC’s offensive prowess than Notre Dame’s defense, especially since Notre Dame gave up a lot of points early in the year. This number could briefly drop past the key number to 6.5.
As for the total, I don’t expect much movement. USC has been excellent offensively, but this number is so high, I don’t expect our best sports betting sites to increase the total, even if there’s a lot of support for the Over.
📺 How to watch USC vs. Notre Dame
- When: Saturday, Oct. 18 @ 7:30 p.m. ET
- Where: Notre Dame Stadium (Notre Dame, Ind.)
- TV: NBC, Peacock
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