Boise State vs. Notre Dame Prediction Today: Latest CFB Week 6 Odds, Expert Picks

Last Updated: October 4, 2025 12:54 PM EDT • 4 minute read X Social Google News Link

Two College Football Playoff teams from a year ago meet for the first time ever on the gridiron as Notre Dame hosts Boise State, and I break down today's matchup with my Boise State vs. Notre Dame prediction. Kickoff from Notre Dame Stadium is set for 3:30 p.m. ET (NBC/Peacock).
Notre Dame is a 20.5-point betting favorite and becoming one of the more popular college football picks after it evened its record at 2-2 with consecutive convincing wins.
My college football predictions for Week 6 back the road underdog at an inflated line while expecting the Broncos' defense to keep Fighting Irish running back Jeremiyah Love relatively in check.
🏈 Boise State vs. Notre Dame prediction today
College football expert picks for Week 6; confidence based on a 1-to-5 star scale.
- Game pick: Boise State +20.5 (-110 via BetMGM) ⭐⭐⭐⭐
- Over/Under pick: Over 62.5 (-110 via FanDuel) ⭐⭐⭐
- Player prop bet: Jeremiyah Love Under 108.5 rushing yards (-115 via BetMGM) ⭐⭐⭐⭐
💡 College football expert picks today
- College football picks against the spread Week 6
- College football player props Week 6
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- College football best bets Week 6
- College football moneyline parlay Week 6
- College football anytime touchdown scorer predictions Week 6
✅ Boise State vs. Notre Dame expert pick today
Track the latest college football scores for line movement and matchup info.
🐴 Boise State +20.5 (-110) ⭐⭐⭐⭐
Notre Dame seems to be finding its groove after two early losses, just like it did last year, when it went on an impressive run from mid-September on and impressed the College Football Playoff committee with statement victories.
But while the Fighting Irish impressively won 56-13 at Arkansas as a 4.5-point favorite, we should not overlook Boise State’s 33-point home win as a 16.5-point favorite against Appalachian State last week.
The Broncos have averaged 49 points per game over their last three games. They did what they should have done against a Mountaineers defense that ranked 100th in explosiveness allowed, torching them for 473 total yards and six plays of 20-plus yards.
The Fighting Irish masked their defensive injuries by jumping out to a big early lead last week, but they're still without two of their best players in the secondary and one of their best pass-rushers. I expect that to catch up with Notre Dame this week when it faces a Broncos team that quietly has a 7.6% chance to make the playoff.
All of the best sports betting sites are in unison with the spread of +20.5 at -110 odds and a 52.38% implied probability. I am making my $10 wager at DraftKings in the hopes of netting $9.09 in profits with a Broncos cover.
💰 Boise State vs. Notre Dame player prop bet today
Our college football player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬇️ Jeremiyah Love Under 108.5 rushing yards (-115) ⭐⭐⭐⭐
We are not accustomed to seeing college football running backs’ rushing yards total this high since Boise State’s own Ashton Jeanty broke the school record for yards in a season last year.
Oddsmakers have inflated Love’s rushing yards total this week as he has set career highs in back-to-back weeks, with 157 rushing yards against Purdue two weeks ago and 70 receiving yards last week. In the game against the Razorbacks, Love also became the first player in school history with two receiving touchdowns and two rushing touchdowns in the same game.
The Broncos have allowed two rushers (both from Air Force) to go Over this projected total. But even when the game script was against them in a 34-7 loss to South Florida, they still hung in well in the trenches, holding the Bulls to 117 yards rushing and 4.2 yards per carry.
This is a confident four-star play, as fellow running back Jadarian Price has an O/U of 70.5 rushing yards and has eaten into Love’s touches with an average of 11.3 rushes per game over the last three weeks.
Under backers will find by far the best value at BetMGM, as Love’s O/U is as low as 98.5 at FanDuel. That makes it worth paying up slightly for the -115 price at 53.49% implied odds, as a $10 winning wager would still return $8.70 in profits.
📊 Boise State vs. Notre Dame odds today
Latest college football odds updated live in real time.
📺 How to watch Boise State vs. Notre Dame
- Date: Saturday, Oct. 4
- Kickoff: 3:30 p.m. ET
- Where: Notre Dame Stadium (Notre Dame, Ind.)
- TV: NBC/Peacock
Most bet college football markets today (BetMGM)
Item | Most Bet Games (Tickets) | Most Bet Spreads (Tickets) | Most Bet Spreads (Handle) | Most Bet Totals (Tickets) |
---|---|---|---|---|
1 | Vanderbilt at Alabama | Texas -5.5 | Texas -5.5 | Vanderbilt at Alabama Over 56.5 |
2 | Iowa State at Cincinnati U | Vanderbilt +11.5 | Alabama -11.5 | Miami Florida at Florida State Over 53.5 |
3 | Texas at Florida | Miami Florida -4.5 | Cincinnati U -1 | Wisconsin at Michigan Over 43.5 |
4 | Miami Florida at Florida State | Iowa State +1 | Notre Dame -21 | Boise State at Notre Dame Over 62.5 |
5 | Wisconsin at Michigan | Michigan -17.5 | Miami Florida -4.5 | Texas at Florida Under 45.5 |
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Mike Spector X social