🩸 Sean Strickland vs. Anthony Hernandez Prediction, Picks & Odds: UFC Fight Night Houston
Last Updated: February 21, 2026 10:00 AM EST • 2 minute read X Social Google News Link
Former UFC middleweight champion Sean Strickland and red-hot contender Anthony Hernandez are ready to collide tonight in the main event of UFC Fight Night Houston at the Toyota Center, as I offer my Sean Strickland vs. Anthony Hernandez prediction.
The 35-year-old Strickland returns to the cage for the first time in over a year against a game Hernandez, who enters on an eight-fight winning streak. With five rounds to work with, I’m backing Hernandez to outwork and outlast his foe before securing the biggest win of his career. The full card is available to stream live with a Paramount+ subscription. Early prelims start at 5 p.m. ET, the prelims kick off at 7 p.m. ET, and the main card begins at 9 p.m. ET. The UFC Fight Night Houston odds have Hernandez as a -275 betting favourite.
🩸 Sean Strickland vs. Anthony Hernandez predictions: UFC Fight Night (Feb. 21)
See all of our UFC picks for this weekend's fights; pick confidence based on a 1-to-5-star scale.
| Market | Pick | Odds | Confidence |
|---|---|---|---|
| Pick to win | Hernandez ML | -275 via BetMGM | ⭐⭐⭐⭐ |
| Best bet | Hernandez DEC | +135 via FanDuel | ⭐⭐⭐⭐ |
💰 Sean Strickland vs. Anthony Hernandez best bet: Hernandez DEC (+135)
Check our best UFC betting sites for the latest odds for this fight.
Anthony Hernandez is known for his elite grappling game, with nine of his 15 career wins coming by submission. Strickland, meanwhile, has never been submitted before in a pro fight, a streak that spans 18 years and 36 fights.
The most likely scenario is that “Fluffy” racks up multiple takedowns and dominates on the ground, but eventually runs out of time and settles for a decision victory.
Prediction: Anthony Hernandez to win by decision (+135 via FanDuel)
🔥 UFC Fight Night predictions
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📊 Sean Strickland vs. Anthony Hernandez odds
Odds via BetMGM; subject to change.
| Sean Strickland | Anthony Hernandez | |
|---|---|---|
| +200 | Win outright | -275 |
| +750 | Win by KO/TKO/DQ | +600 |
| +3000 | Win by submission | +290 |
| +400 | Win by decision | +140 |
| Over: -180 | Over/Under 4.5 rounds | Under: +140 |
📈 UFC Fight Night odds
Our Andrew Reid explores the latest UFC Fight Night odds ahead of Saturday night's event in Houston.
⚖️ Sean Strickland vs. Anthony Hernandez tale of the tape
| Sean Strickland | Anthony Hernandez | |
|---|---|---|
| 35 | Age | 32 |
| 6-foot-1 | Height | 6-foot |
| 185 | Weight | 185 |
| 76” | Reach | 75” |
| 29-7 | Record | 15-2 |
| 11 | Wins by KO | 3 |
| 4 | Wins by submission | 9 |
| 0/0 | Head-to-head | 0/0 |
📺 How to watch Sean Strickland vs. Anthony Hernandez: UFC Fight Night Houston
- Date: Saturday, Feb. 21
- Time: 5 p.m. ET (early prelims), 7 p.m. ET (prelims), 9 p.m. ET (main card)
- Location: Toyota Center (Houston)
- TV: Paramount+
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