Premier League Predictions & Odds: EPL Best Bets, Expert Picks for Matchweek 4

Last Updated: September 12, 2025 9:48 AM EDT • 4 minute read X Social Google News Link

My Premier League predictions and odds headline our soccer picks for Matchweek 4.
I've recommended three bets for the weekend's action, including an Under, a moneyline pick, and a two-leg same-game parlay for the match at Emirates Stadium between Arsenal and Nottingham Forest.
🏴 Premier League predictions & odds for Matchweek 4
Here are my Premier League predictions for Matchweek 3. Odds are live and updated in real time.
- Arsenal vs. Nottingham Forest: Arsenal and Over 2.5 goals (+100 via BetMGM) ⭐⭐⭐⭐
- Everton vs. Aston Villa: Under 2.5 goals (-125 via DraftKings) ⭐⭐⭐⭐
- Fulham vs. Leeds: Fulham ML (+100 via DraftKings) ⭐⭐⭐
💰 Arsenal vs. Nottingham Forest: Arsenal & Over 2.5 goals ⭐⭐⭐⭐

Nottingham Forest looks forward to a new chapter under former Tottenham boss Ange Postecoglou. That means the rest of us can anticipate more goals in Forest matches. Postecoglou has made no excuses for how he sets his teams out. He expects his players to play on the front foot relentlessly, with a high press that leads to lots of scoring chances for the club, and just as many against.
Additionally, he never focused on dead-ball situations with Spurs, which resulted in Tottenham being arguably the Premier League's worst team from corners and free kicks. Arsenal is one of the best, particularly from corners.
Arsenal center back William Saliba won't feature due to an injury he suffered against Liverpool, which could open the door for a goal from the visitors. Even without Postecoglou at the helm, two of Forest's three matches featured more than two goals, and Arsenal's only home match thus far ended with them bagging five against an overwhelmed Leeds side.
BetMGM offers the best value of the best sports betting sites at +100, and a winning $10 bet will profit $10.
📊 Arsenal vs. Nottingham Forest live odds
💰 Everton vs. Aston Villa: Under 2.5 goals ⭐⭐⭐⭐

Aston Villa hasn't won a match, and the team has failed to score a goal in its first three. And I don't see Aston Villa breaking out offensively against a resolute Everton at Goodison Park. If there's anything David Moyes specializes in, it's providing his team with the tools required to thrive defensively, especially at home.
The Toffees have played two matches at home in all competitions, outscoring opponents 4-0. That includes a 2-0 over Brighton in the Premier League.
Unai Emery will focus his attention on shoring up the team's defense for Villa to end its slump. The last four meetings between these sides at Goodison Park resulted in the Under 2.5 goals hitting.
📊 Everton vs. Aston Villa live odds
💰 Fulham vs. Leeds United: Fulham ML ⭐⭐⭐
Leeds United remaining in the Premier League will depend on its away form. Most newly promoted teams struggle mightily in enemy environments, and it didn't start well for manager Daniel Farke, whose side lost 5-0 at Arsenal in its first road match.
Nobody expects results against the league's juggernauts to determine their fate, but matches like the one this Saturday at Craven Cottage will. Fulham tied Manchester United 1-1 in its only match at home thus far and has won two straight against Leeds at Craven Cottage.
Fulham deserved better than the 2-0 defeat during its last match at Stamford Bridge. A questionable VAR call denied Marco Silva's side the opener, and that changed the complexion of the match. And they have their new shiny asset, former Shakhtar Donetsk winger Kevin, at their disposal.
While I don't expect him to start, he could prove decisive off the bench. If he does start, keep your eye on this budding 22-year-old star. The even-money odds at DraftKings will yield a $10 profit on a winning $10 bet.
📊 Fulham vs. Leeds United live odds
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Gary Pearson X social