Crystal Palace vs. Liverpool Prediction Today: Matchweek 6 Best Bets

My Crystal Palace vs. Liverpool prediction calls for a low-scoring affair with a Jean-Philippe Mateta doing his best to lead Palace to a victory.
Pictured: Alexander Isak of Liverpool. Photo by Alfie Cosgrove/News Images/Sipa USA.

My Crystal Palace vs. Liverpool prediction examines how the Reds' perfect start is at risk of coming to an end following a string of dramatic victories. The action from Selhurst Park in London gets underway at 10 a.m. ET (Peacock).

Palace are in fifth place after a positive start to the season. Still, first-place Liverpool is a -111 the betting favorite after beginning the season with a perfect record in all competitions. My soccer picks look at how Palace can stymie Liverpool in a tight, low-scoring contest. I also analyze a Palace striker who’s set to wreak havoc against Liverpool’s defense.


⚽ Crystal Palace vs. Liverpool prediction

Soccer picks for Saturday; odds subject to change.

  • Moneyline pick: Draw (+275 via bet365) ⭐⭐⭐⭐
  • Against the spread pick: Crystal Palace +0.5 (-120 via DraftKings) ⭐⭐⭐
  • Over/Under pick: Under 2.5 goals (+110 via Caesars) ⭐⭐⭐⭐⭐

📝 Crystal Palace vs. Liverpool best bet

⬇️  Under 2.5 goals (+110) ⭐⭐⭐⭐⭐

Crystal Palace vs. Liverpool Prediction, Odds & Expert Picks: Premier League Matchweek 6 Best Bets
Pictured: Crystal Palace goalkeeper Dean Henderson makes a save during a Premier League match at Selhurst Park. Photo by Jordan Pettitt/PA Images/Alamy Images/Sipa USA

Crystal Palace are off to a surprise start to the season despite losing some key players during the summer transfer window. Although they’re not perfect like Liverpool, Palace are undefeated like the Reds. 

Manager Oliver Glasner’s side is expected to put up another formidable challenge Saturday against the reigning Premier League champions. But don’t expect it to be a game packed with goals. 

Even though their last meeting ended 2-2 in the Community Shield - which Palace won on penalties - I’m anticipating that this game will be much tighter and finish Under 2.5 goals like the previous three meetings in the Premier League.

Liverpool’s potent attack, headlined by Alexander Isak and Mohamed Salah, is one of the best in the league, and Palace poses a real challenge. The task is even harder for Liverpool without Hugo Ekitike, who will be suspended after picking up a red card in his last game.

A winning $10 bet at Caesars will pay a profit of $11, and carry an implied win percentage of 47.62%.

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💰 Best Crystal Palace vs. Liverpool player prop bet

⬆️  Jean-Philippe Mateta Over 2.5 shots (-150) ⭐⭐⭐⭐⭐

Crystal Palace vs. Liverpool Prediction, Odds & Expert Picks: Premier League Matchweek 6 Best Bets
Pictured: Jean-Philippe Mateta of Crystal Palace and Tyrick Mitchell of Crystal Palace celebrate. Photo by Harvey Murphy/News Images/Sipa USA.

Liverpool might be in control for a majority of Saturday’s game, but that shouldn’t stop Crystal Palace forward Jean-Philippe Mateta from being a threat in attack.

Although playmaker Eberechi Eze left for Arsenal, Mateta is still getting his chances in front of goal after averaging around two shots a game in the Premier League. He has a flair for creating chances out of thin air, so I think that it’s a decent bet that Mateta will get Over 2.5 shots against Liverpool.

Outside of a 30-minute, shotless appearance last October, Mateta is averaging 2.5 shots against Liverpool. A successful $10 bet over at bet365 nets a profit of $6.66, and the -150 odds implied a 60% chance of the bet hitting.

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📊 Crystal Palace vs. Liverpool odds: Matchweek 6

Premier League odds update live in real time.

📈 Crystal Palace vs. Liverpool betting odds analysis

Crystal Palace could see an uptick in their odds if Ismaila Sarr returns from injury. But it’s unlikely that Liverpool’s odds as favorites will lessen much. Especially considering that most of their stars will be fresh after some of them were rested for the team’s midweek win over Southampton in the Carabao Cup.


🔢 Crystal Palace vs. Liverpool results

Team vs. Team history courtesy of 11v11.com.

Date Competition Result Location
Aug. 10, 2025 FA Community Shield Crystal Palace 2 - 2 Liverpool Wembley Stadium (London)
May 25, 2025 Premier League Liverpool 1-1 Crystal Palace Anfield (Liverpool)
Oct. 4, 2024 Premier League Crystal Palace 0-1 Liverpool Selhurst Park (London)
April 14, 2024 Premier League Liverpool 0-1 Crystal Palace Anfield (Liverpool)
Dec. 9, 2023 Premier League Crystal Palace 1-2 Liverpool Selhurst Park (London)

📺 Crystal Palace vs. Liverpool game info

  • When: Saturday, Sept. 27
  • Kickoff: 10 a.m. ET
  • Where: Selhurst Park (London)
  • How to watch: Peacock

❓ Crystal Palace vs. Liverpool FAQs

Who is favored to win Crystal Palace vs. Liverpool?

Liverpool are the -111 road betting favorite at Crystal Palace.

What is the spread for Crystal Palace vs. Liverpool?

Liverpool are at -0.5, with odds of -115 over at DraftKings.

What is the Over/Under for Crystal Palace vs. Liverpool?

The total for Crystal Palace vs. Liverpool has been set at 2.5, with the Under at +110.

What are the best bets for Crystal Palace vs. Liverpool?

My best bets for Crystal Palace vs. Liverpool are Under 2.5 goals and Jean-Philippe Mateta over 2.5 shots

When is the Crystal Palace vs. Liverpool game?

Crystal Palace vs. Liverpool kicks off at 10 a.m. ET from Selhurst Park in South London.

How do soccer odds work?

When betting on soccer, the spread shows how many goals the favorite needs to win by in order to cash the bet. For example, a favorite of -1.5 must win by 2 or more goals to cover the spread, while an underdog at +1.5 must win outright or lose by fewer than 1 goal to cover the spread.

Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total will be higher or lower than the set number.

You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.

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