49ers vs. Eagles Same Game Parlay: NFL Wild Card Weekend SGP Picks

Philadelphia has the fifth-ranked scoring defense and stifled playoff offenses like Buffalo and Green Bay during the year.
San Francisco 49ers running back Christian McCaffrey (23) runs as we break down our 49ers vs. Eagles same game parlay.
Pictured: San Francisco 49ers running back Christian McCaffrey (23) runs as we break down our 49ers vs. Eagles same game parlay. Photo by Kyle Terada-Imagn Images
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My 49ers vs. Eagles same-game parlay for NFL Wild Card Weekend envisions a dominant performance by Philadelphia against a San Francisco team that has been sluggish on defense throughout the year, and is fresh off one of its worst performances on offense.

The action for 49ers vs. Eagles kicks off from Lincoln Financial Field in Philadelphia, Sunday at 4:30 p.m. ET (FOX). The Eagles are 6-point betting favorites as part of our NFL playoff predictions.


🏈 49ers vs. Eagles same-game parlay: NFL Wild Card Weekend

See the latest NFL odds and our experts' NFL picks for every game this season.

Parlay bet Odds (DraftKings) Confidence
Eagles -6 -108 ⭐⭐⭐⭐
Saquon Barkley Over 82.5 rushing yards -110 ⭐⭐⭐⭐
Christian McCaffrey Over 44.5 receiving yards -113 ⭐⭐⭐⭐

Best SGP odds: +475 via DraftKings ($10 to win $47.50)


🚀 Best 49ers vs. Eagles SGP & parlay picks

See all of our NFL same-game parlay bets for every playoff game.

Eagles -6 (-108) ⭐⭐⭐⭐

Though San Francisco’s defense fought valiantly in a Week 18 loss to the Seahawks, its offense couldn’t connect against Seattle’s defense, mustering just 3 points. Philadelphia has the fifth-ranked scoring defense and stifled playoff offenses like Buffalo and Green Bay during the year.

Saquon Barkley Over 82.5 rushing yards (-110) ⭐⭐⭐⭐

Correlating to our prediction of a positive game script for Philadelphia, Saquon Barkley should produce against a San Francisco defense that has allowed Kenneth Walker, Tony Pollard and Quinshon Judkins to shred this rushing yardage total against it over the past five games. Barkley had a pair of 120+ yard rushing outputs in December.

Christian McCaffrey Over 44.5 receiving yards (-113) ⭐⭐⭐⭐

The Eagles allow the second-most yards per reception to opposing running backs, setting up Christian McCaffrey for a solid receiving output that correlates to our projected negative game script as San Francisco is forced to chase the game. Though his production through the air has slowed recently, McCaffrey has cleared this line in 10 out of 17 games.

💡 More NFL predictions

Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game this season.


📺 How to watch 49ers vs. Eagles: NFL Wild Card Weekend

  • Date: Sunday, Jan. 11
  • Kickoff: 4:30 p.m. ET
  • Location: Lincoln Financial Field (Philadelphia)
  • TV: FOX

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