NFL 2+ Touchdown Scorer Predictions: Best TD Picks to Score Twice in Week 16
Last Updated: December 20, 2025 4:39 PM EST • 3 minute read Google News Link
My NFL 2+ touchdown parlay today focuses on two running backs to find pay dirt with the 2-leg parlay returning $900 on a $10 wager.
My NFL Week 16 predictions explain why Philadelphia Eagles running back Saquon Barkley and Kansas City Chiefs running back Kareem Hunt are my best TD picks to score two touchdowns this week.
🏈 NFL 2+ touchdown scorer predictions for Week 16
See all of our experts' NFL picks for Week 16 based on the latest NFL odds.
| Player | Odds (FanDuel) | Profit ($10 bet) | Confidence |
|---|---|---|---|
| Saquon Barkley, RB, Eagles | +550 | $55 | ⭐⭐⭐⭐⭐ |
| Kareem Hunt, RB, Chiefs | +1300 | $130 | ⭐⭐⭐⭐ |
| Combined | +9000 | $900 | --- |
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Saquon Barkley, RB, Eagles (+550) ⭐⭐⭐⭐⭐️
Barkley hasn't had the year he expected to have in 2025, but he has an opportunity to finish the year strong while gearing up for the playoffs. The good news for Barkley is he's going up against a Washington Commanders defense that will have a near impossible task of shutting down this Eagles offense.
Barkley has been a weapon in both the rushing and passing attack this year, combining for eight touchdowns on the season. The Commanders defense ranks fifth to last in rushing yards allowed per game, and they have gotten worse as the season has progressed. I expect the Eagles' game plan to feature Barkley as much as possible in a must-win game for playoff positioning, and if they can execute, he should have no issues cashing this leg of the 2+ touchdown scorer parlay.
Kareem Hunt, RB, Chiefs (+1300) ⭐⭐⭐⭐
Hunt enters Week 16 with a completely new offense surrounding him. The Chiefs will be without star quarterback Patrick Mahomes for the rest of the season, and Rashee Rice is also going to be missing this game with a concussion. Fortunately for Kansas City, it'll face the two-win Tennessee Titans. The Chiefs will need to heavily feature the rushing attack to help Gardner Minshew avoid turnovers in his first start of the year.
Tennessee's defense has allowed the second-most rushing touchdowns (19), and while the Chiefs have nothing to play for in this game, neither do the Titans, who are barely competitive at this point in the season. I expect the Chiefs offense to still be able to put up points, and Hunt will be the red-zone beneficiary.
🚀 Best NFL 2+ touchdown scorer parlay
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LJ Blut