🏀 Creighton vs. St. John's Prediction & Odds: College Basketball Picks Today (Feb. 21)

Our Creighton vs. St. John’s prediction expects more of a defensive struggle in the second regular-season meeting between these Big East rivals.
St. John’s Red Storm guard Lefteris Liotopoulos shoots against the Marquette Golden Eagles, and we're backing his team to cover with our Creighton vs. St. John's prediction.
Pictured: St. John’s Red Storm guard Lefteris Liotopoulos shoots against the Marquette Golden Eagles, and we're backing his team to cover with our Creighton vs. St. John's prediction. Photo by Jeff Hanisch via Imagn Images.
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Creighton is coming off arguably the most shocking upset in the Big East while No. 17 St. John’s looks for a season-high 13th straight win when it hosts the Bluejays at Madison Square Garden in New York this afternoon. 

The Red Storm are 12.5-point betting favorites for today’s tip at noon ET (FOX). As part of my college basketball predictions today, my Creighton vs. St. John's prediction expects both coaches to make defensive adjustments from the 90-73 Red Storm win on Jan. 10, leading to the Under cashing. In addition to the Under, I offer a score prediction and my best player prop bet.


🏀 Creighton vs. St. John's picks & odds today: Feb. 21

See all of our experts' college basketball picks based on the latest college basketball odds; picks rated on a 1-to-5 star confidence scale based on betting value.

Bet type Prediction Units Confidence
Game prediction St. John’s -12.5 (-110) 1u -> 0.91u  ⭐⭐⭐
Over/Under total Under 154.5 (-115) 2u -> 1.74u  ⭐⭐⭐⭐
Player prop bet Bryce Hopkins Over 7.5 rebounds (-114) 1u -> 0.88u  ⭐⭐⭐⭐

Total wagered: 4.0 units | Max profit: 3.53 units


💰 Creighton vs. St. John's prediction & best bet

Under 154.5 (-115)

Entering this season, the five matchups between Rick Pitino and Greg McDermott were mostly played at St. John’s preferred pace, with only one game finishing with 65 or fewer possessions. But the Bluejays limited St. John’s to 67 possessions in the first matchup this year, and one cannot expect the Red Storm to again make 52.% of its 3-point attempts in the rematch.

St. John’s has faced five opponents twice this season, and four of those five rematches finished with either the same or fewer total points than the first meeting. That includes an overtime battle against Xavier at home.

Score prediction: St. John’s 83, Creighton 68


🔥 Best Creighton vs. St. John's player prop bet

Bryce Hopkins Over 7.5 rebounds (-114)

St. John’s has gone to a “three big” lineup of late with Bryce Hopkins, Dillon Mitchell, and Zuby Ejiofor, and the Red Storm have controlled the backboards as a result. 

Hopkins in particular has elevated his play of late, ranking second on the team with 15 points and 6.9 rebounds per game during the team’s 12-game winning streak. He is a big reason the team has averaged 12.6 offensive rebounds per game during the streak, while the Red Storm lead the conference and sit 20th nationally in offensive rebounds per game (13.5).

Hopkins is coming off of his first double-double with St. John’s as he totaled 23 points and matched a season-high with 10 rebounds against Marquette. He also ranks in the top 12 of all players in both offensive and defensive rebounding rate in league play.


🚀 Creighton vs. St. John's same-game parlay

St. John’s is amid the nation’s third-longest winning streak, and I am concerned about an emotional letdown from the Bluejays, who played inspired after the passing of Josh Dix’s mother in the upset of UConn. The early noon tip should help the Under cash, while Hopkins exceeds his projected rebounding total for the fourth straight game. 

💵 Creighton vs. St. John's SGP picks

  • St. John’s -12.5 (-110)
  • Under 154.5 (-115)
  • Bryce Hopkins Over 7.5 rebounds (-114)

Best odds: +570 via DraftKings (1u -> 5.7u)


💡 How I'm betting Creighton vs. St. John's

Follow all of our college basketball analysis and expert predictions this season.

Creighton has been all over the place from an ATS perspective, with two wins over top-four Big East teams combined with a loss to DePaul for the first time since 2015 in its last five games. 

The Bluejays are likely slightly overvalued in this matchup after upsetting UConn, with the Huskies falling to 5-14 ATS as double-digit favorites this season. That is why I’m allocating two of my four units to the Under, especially since St. John’s has allowed opponents to score fewer than seven points per game off its turnovers over the last 12.


📊 Live Creighton vs. St. John's odds

Most of the top sports betting sites opened slightly higher at St. John’s -13.5, but have since leveled out at -12.5. The total had a much wider gap with opening numbers between 153.5 and 155.5, but the Under has gotten much of the support and is now trading at a high of 154.5. 


📈 Creighton vs. St. John's betting trends

Creighton Statistic St. John’s
14-13 W-L record 21-5
9-18 ATS record 13-13
14-13 O/U record 12-14
2-3 Last 5 games 5-0

📺 How to watch Creighton vs. St. John's

  • Date: Saturday, Feb. 21
  • Tipoff: Noon ET
  • Location: Madison Square Garden (New York)
  • TV: FOX

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