Celtics vs. Knicks Prediction Tonight: Game 4 Odds & Expert Picks

Boston looks to even the series against New York as we offer our Celtics vs. Knicks prediction for tonight's Game 4.

Mike Spector

Last updated: May 12, 2025 4:30 PM EDT • 3 min read

Celtics vs. Knicks prediction — Pictured: Boston Celtics guard Jaylen Brown reacts after a play against the New York Knicks in the second quarter during Game 2 of the second round for the 2025 NBA Playoffs. Photo by David Butler II / Imagn.

The Boston Celtics are the 6.5-point favorites at our best sports betting sites, and they'll look to even the series against the New York Knicks tonight during Game 4 from Madison Square Garden (7:30 p.m. ET, ESPN) as we offer our Celtics vs. Knicks prediction and NBA picks.

💰 Celtics vs. Knicks expert picks for Game 4

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✅ Against the spread pick: Knicks +6.5 (-110 via FanDuel) ⭐⭐⭐
✅ Moneyline pick: Celtics (-245 via bet365) ⭐⭐⭐
✅ Over/Under pick: Under 209 (-110 via DraftKings) ⭐⭐

🏀 Game 4 prediction & best bet

🎯 Score prediction: Celtics 105, Knicks 101

Boston’s shooting woes finally subsided in Game 3. It shot a blistering 50% (20-for-40) from beyond the arc and made 12 of its first 19 threes to build a comfortable lead.

While the Knicks were never ahead in Game 3, and have only led for 12 minutes and 15 seconds of this series, I also do not foresee them trailing by 20-plus points at any point for a fourth consecutive game.

Seven of New York’s nine postseason games thus far have been decided by six or fewer points. If the Knicks can avoid another slow start (they have trailed at the half by 50 combined points through the first three games), the Celtics should be vulnerable once again with the pressure on them late.

Jalen Brunson still has not had a 30-point game in this series, and I expect the Clutch Player of the Year winner to have his best game yet, with this game to be decided in the final minute.

✅ Best bet: Knicks +6.5 (-110 via FanDuel)

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📈 Celtics vs. Knicks odds

Live updated odds from our best sports betting sites.

🔢 Celtics vs. Knicks betting insights

Betting info provided by BetMGM.

The Celtics opened as 6.5-point betting favorites, and the line hasn't changed
In the hours before tipoff, 64% of the bets and 38% of the money are on the Celtics to cover
The total decreased from 209.5 to 208.5
The Over on 208.5 is -115, the Under is -105
Currently, 79% of the bets and 89% of the money are on the Over
The Celtics moved from -235 to -250 moneyline favorites

🪧 Game 4 opening odds

Opening odds via BetMGM.

Spread: Celtics -6.5 (-105) | Knicks +6.5 (-115)
Moneyline: Celtics -235 | Knicks +195
Over/Under: Over 209.5 (-110) | Under 209.5 (-110)

🚑 Celtics vs. Knicks injury report

Follow the official NBA injury report for more injury news.

📡 How to watch Celtics vs. Knicks live (Game 4)

📅 Monday, May 12
🕗 7:30 p.m. ET
📍 Madison Square Garden (New York)
📺 ESPN | 🛜 Sling TV, YouTube TV

🔮 Today's NBA Expert picks

💵 Best NBA betting sites

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Written By:
Mike Spector

Mike started in the sports writing industry in July 2019, and gained a lot of followers in his first year after finishing with the No. 2 overall record in an annual NFL betting competition, which made picks against the spread, and from an Over/Under and moneyline perspective. Mike is an avid fan of the NFL, MLB, tennis, and all college sports. In his opinion, March Madness is the best sporting event there is, and he's especially euphoric starting with conference tournament time in college basketball. Mike's a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." When making wagers, Mike always scours the best odds at all of the major sports betting sites, where he mostly sifts through DraftKings, FanDuel, BetMGM, and bet365. He's tried several others and is of the firm belief that bettors should not just stick to one sportsbook, as there is always likely better value to be had with the same wager. In addition, while Mike received his undergraduate degree from Villanova University, he has no issue betting against the Wildcats when it comes to college basketball wagering, and suggests other bettors should always put their “head” before their “hearts.”