Argonauts vs. Roughriders Prediction: CFL Week 19 Odds, Expert Picks & Best Bets

Last Updated: October 10, 2025 8:00 AM EDT • 2 minute read X Social Google News Link

My Argonauts vs. Roughriders prediction has Saskatchewan willing its way to a blowout victory over the shorthanded visitors.
My CFL picks back the Roughriders as a 10-point betting favorite over the Argonauts on Friday, with kickoff from Mosaic Stadium in Regina, Sask., set for 9 p.m. ET (TSN/CFL+).
My CFL prediction also expects a Roughriders star to score a touchdown, and he's catching +210 odds in his second game back from injury.
🏈 Argonauts vs. Roughriders predictions
CFL expert picks for Friday; odds subject to change.
- Game prediction: Roughriders -10 (-112 via DraftKings) ⭐⭐⭐⭐
- Over/Under pick: Over 50 (-110 via Caesars) ⭐⭐⭐
- Player prop bet: Kian Schaffer-Baker anytime touchdown (+210 via BetMGM) ⭐⭐⭐⭐
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✅ Argonauts vs. Roughriders expert pick
🤠 Roughriders -10 (-112) ⭐⭐⭐⭐
It's hard not to like the home favorite when the Argonauts have nothing left to play for at this point.
Not only is Toronto down its two best quarterbacks - Chad Kelly and Nick Arbuckle - but it's already been eliminated from playoff contention.
Quarterback Jarret Doege will start against Saskatchewan, and he is a significant downgrade from Arbuckle. He has thrown for 565 yards with three touchdowns and five interceptions in three games this season.
The Roughriders, meanwhile, can claim the division title with a win on Friday (or a Calgary Stampeders loss). Saskatchewan won the last meeting between these sides by just seven points on June 20, but that game was in Toronto against Arbuckle. Friday's final score shouldn't look anywhere near as close.
DraftKings has the best odds available at the time of publish. These -112 odds to bet Roughriders -10 feature an implied probability of 52.83%, and a winning $10 bet would profit $8.93.
💰 Best Argonauts vs. Roughriders player prop bet
Our player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
🔥 Kian Schaffer-Baker anytime touchdown (+210) ⭐⭐⭐⭐
Kian Schaffer-Baker will likely be more involved in the offense this week after a quiet return from a foot injury.
Schaffer-Baker was targeted five times in the Week 18 win against the Ottawa Redblacks, catching four passes for 40 yards. With Saskatchewan being listed as the Grey Cup favorite at our best sports betting sites, now is the time for QB Trevor Harris to regain familiarity with one of his best receivers - especially since coach Corey Mace may rest both after clinching the division title.
You can bet Schaffer-Baker to reach the end zone at +210 odds via BetMGM, which implies a 32.26% chance that he'll score and turns a $10 bet into a $21 profit if he does.
📊 Argonauts vs. Roughriders odds
Latest CFL odds updated live in real time.
📺 How to watch Argonauts vs. Roughriders: CFL Week 19
- Date: Friday, Oct. 10
- Kickoff: 9 p.m. ET
- Where: Mosaic Stadium (Regina, Sask.)
- TV: TSN/CFL+
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