Oklahoma State vs. Oregon Prediction, Odds & Expert Picks: College Football Week 2 Best Bets
We're diving into our Oklahoma State vs. Oregon prediction for Week 2 as part of our college football picks. The game is scheduled for Saturday, Sept. 6 at 3:30 p.m. ET (CBS) from Autzen Stadium in Eugene, Ore.
Oregon is a massive 28.5-point betting favorite over Oklahoma State in what may be an underwhelming contest. Make sure to check out the rest of our college football predictions for Week 2 so that you don’t miss any profitable picks, including our player prop for Dante Moore.
🏈 Oklahoma State vs. Oregon expert picks & predictions
College football expert picks made Thursday; odds subject to change.
- Moneyline pick: Oregon ML (-7000 via Caesars) ⭐
- Against the spread pick: Oregon -28.5 (-108 via FanDuel) ⭐⭐
- Over/Under pick: Under 55.5 (-105 via BetMGM) ⭐⭐⭐
📝 Oklahoma State vs. Oregon preview & best bet
Track the latest college football scores for line movement and matchup info.
⬇️ Under 55.5 (-105) ⭐⭐⭐
It’s difficult to imagine Week 1 going worse for Oklahoma State. Starting quarterback Hauss Hejny went down with an injury and is expected to miss significant time. Joining him on the injury report are center Kasen Carpenter and defensive end DeSean Brown. While the Cowboys did manage to notch a 20-point home victory over UT Martin, it feels like an empty win.
Those injuries have helped move the opening spread for this game from Oregon -23.5 to -28.5, but the total hasn’t ticked down in response. After opening at 58.5, it still sits at a generously high 55.5. That means Oregon’s projected total has increased from 41 to 42 while Oklahoma State’s has fallen from 17.5 to 13.5. I hold serious questions about whether the Cowboys can get to that number.
Further, it’s unclear whether the Ducks will even want to reach the 42 they need to score to push this one Over. Head coach Dan Lanning may opt for a more conservative, slow-paced game script after his Ducks get out to an early lead, especially against an injury-riddled team captained by a legend of the sport in head coach Mike Gundy.
The total hasn’t dropped enough yet, so bet the Under on 55.5 for -105 (51.2%) at BetMGM for a $9.52 profit on a $10 bet. Get this number before it dips further.
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💰 Best Oklahoma State vs. Oregon player prop bet
Our college football player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬇️ Dante Moore Under 242.5 passing yards (-114) ⭐⭐
Oregon quarterback Dante Moore won’t need to do much for the Ducks to win this game. He may not even need to do that much for them to cover.
Oklahoma State is surely demoralized after the laundry list of injuries suffered last week at key positions. While the Cowboys will doubtlessly surrender plenty of points and yards to the Ducks, it’s unclear how long Lanning will need Moore to throw – or even need him to play.
Lanning was happy to sub out last year’s starter Dillon Gabriel during multiple blowout wins to preserve him. Moore may need the reps, but the Ducks could be content to stick with the ground game like they did last week, even if the starting signal-caller remains in the game.
Moore completed 78.3% of his throws for 9.3 yards per attempt and three scores against Montana State in Week 1. But since Lanning only let him throw 23 times, he totaled just 213 passing yards.
Expect something similar this week. Back Moore for under 242.5 passing yards at -114 (53.3%) through FanDuel for an $8.77 profit on a $10 wager.
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📊 Oklahoma State vs. Oregon odds: Week 2
College football odds update live in real time.
📈 Oklahoma State vs. Oregon opening odds
- Moneyline: Oklahoma State +1000 | Oregon -5000
- Spread: Oklahoma State +23.5 (-110) | Oregon -23.5 (-110)
- Over/Under: Over 58.5 (-115) | Under 58.5 (-108)
🔍 Oklahoma State vs. Oregon odds analysis
The spread for Oklahoma State vs. Oregon opened at a sizable Oregon -23.5, but the injuries to Oklahoma State have been pushing that number all the way out to 28.5. I wouldn’t be surprised to see it keep going beyond the key number of 28.
It took a bit longer for the total to move accordingly, but that's now dropped from 58.5 to 55.5. That implies a total of 13.5 for Oklahoma State. It's a low number, but it may still be generous for this matchup due to the injuries. The downward movement will likely continue.
🔢 Oklahoma State vs. Oregon stats
Season stats courtesy of Sports Reference.
| Oklahoma State | Statistic (per game) | Oregon |
| 27 | Points | 59 |
| 7 | Points allowed | 13 |
| -1 | Turnover margin | 0 |
| 232 | Passing yards | 253 |
| 127 | Rushing yards | 253 |
| 109 | Passing yards allowed | 198 |
| 116 | Rushing yards allowed | 46 |
| 5.0 | Net yards per play | 7.9 |
🚑 Oklahoma State vs. Oregon injury report
📺 Oklahoma State vs. Oregon game info
- When: Saturday, Sept. 6
- Kickoff: 3:30 p.m. ET
- Where: Autzen Stadium (Eugene, Ore.)
- How to watch: CBS/Paramount+
❓ Oklahoma State vs. Oregon FAQs
Who is favored to win Oklahoma State vs. Oregon?
Oregon is a massive betting favorite versus Oklahoma State, and the odds keep moving in the Ducks' favor.
What is the spread for Oklahoma State vs. Oregon?
The spread for Saturday’s Oklahoma State vs. Oregon game is a whopping -28.5 in favor of the Ducks, which has ticked up from the opening number of 23.5.
What is the Over/Under for Oklahoma State vs. Oregon?
The Over/Under for Oklahoma State vs. Oregon is 57.5, a tick lower than the 58.5 where it opened.
What are the best bets for Oklahoma State vs. Oregon?
My best bets for Oklahoma State vs. Oregon are Under 55.5 for -105 (51.2%) at BetMGM and Dante Moore Under 242.5 passing yards for -114 (53.3%) at FanDuel.
When is the Oklahoma State vs. Oregon game?
The Oklahoma State vs. Oregon game is scheduled for 3:30 p.m. ET on Saturday, Sept. 6.
How do college football odds work?
When betting on college football, the point spread shows how many points the favorite needs to win by in order to cash the bet. For example, a favorite of -3 must win by more than 3 points to cover the spread, while an underdog at +3 must win outright or lose by fewer than 3 points to cover the spread.
Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total will be higher or lower than the set number.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
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