College Football Playoff Odds 2025: 12-Team CFP Prediction & Best Bets After Week 8
Through eight weeks of the college football season, chaos has reigned, and while the top of College Football Playoff odds are still being dominated by the Big Ten and SEC, it looks like this year's CFP will have a few new faces.
In Week 8 alone, four teams ranked in the top 10 of the AP poll lost, and the latest AP top 25 has teams like Indiana, Georgia Tech, and Vanderbilt ranked in the top 10, with the new era of college football no longer being owned by blue blood programs.
With just six weeks left in the regular season, and the College Football Playoff odds race still wide open, the best teams to target with your college football picks are programs that aren't historically dominant.
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🔮 12-team College Football Playoff prediction
| Seed | Team | CFP odds |
|---|---|---|
| 1 | Ohio State | Odds pulled |
| 2 | Alabama | -450 via Caesars |
| 3 | Indiana | -2000 via Caesars |
| 4 | Oregon | -300 via Caesars |
| 5 | Texas A&M | -325 via Caesars |
| 6 | Georgia | -200 via Caesars |
| 7 | Texas Tech | -150 via DraftKings |
| 8 | Miami | -270 via DraftKings |
| 9 | Notre Dame | -150 via Caesars |
| 10 | Oklahoma | +225 via Caesars |
| 11 | Missouri | +300 via Caesars |
| 12 | South Florida | +300 via Caesars |
🎯 Best College Football Playoff bets
🏴☠️ Texas Tech (-150)
- SP+ ranking: No. 4 (No. 7 offense, No. 13 defense, No. 42 special teams)
- Toughest games left: vs. No. 11 BYU (Nov. 8)
Yes, Texas Tech just lost to Arizona State. But for those who missed out on backing the Red Raiders when they were plus-money at our best college football betting sites, this is the time to strike. Tech was -450 to make the CFP this time last week, implying an 81.82% probability they'd reach the College Football Playoff, but with these odds now at -150, a $10 bet pays a $6.67 profit.
Sure, $6.67 might not seem like you're going to win a bag the size of the one Texas Tech booster Cody Campbell dropped to help build this roster via the portal, but when half the teams worth betting have CFP odds in the -270 to -2000 range, -150 doesn't seem so bad. Plus, Texas Tech only lost because starting QB Behren Morton missed the game, and freshman Will Hammond struggled in his first career start on the road against last year's Big 12 champ.
And even still, Texas Tech nearly came back to win the game thanks to all the talent this team has on both sides. So with Morton expected to be back soon, the Red Raiders are still poised to win this conference behind an offense with a plethora of weapons like Cameron Dickey, Caleb Douglas, and Terrance Carter, and a defense with one of the country's most disruptive front sevens, thanks to David Bailey and Jacob Rodriguez.
It doesn't hurt that Texas Tech only has one truly tough opponent left on its schedule, No. 11 BYU, and the Red Raiders play the Cougars in Lubbock. The expectation for head coach Joey McGuire was to make the CFP, and his team still should because this is the most talented roster in the conference.
Notre Dame is an equally worthy team to bet at this -150 price after the Fighting Irish beat the last tough opponent on their schedule in Week 8 (USC) behind a 228-yard rushing performance from Jeremiyah Love.
🐯 Missouri (+300)
- SP+ ranking: No. 8 (No. 17 offense, No. 11 defense, No. 119 special teams)
- Toughest games left: at No. 10 Vanderbilt, vs. No. 3 Texas A&M, at No. 13 Oklahoma
This is a bold bet, but Missouri has been my favorite plus-money CFP bet since Texas Tech's odds shortened to minus-money a few weeks ago. So obviously, I was sweating it out during the Tigers' double OT win against Auburn in Week 8, which included what Eliah Drinkwitz thought was a game-winning field goal at one point.
But Missouri survived at Jordan-Hare thanks to its violent front seven, led by Zion Young, who might be the scariest player in college football. With a defense that includes several future NFL players like Young and Damon Wilson II, an offense that has the best running back in the SEC (Ahmad Hardy), a mobile QB (Beau Pribula), and a handful of dynamic pass catchers, Missouri should have a shot at the CFP.
The Tigers have three ranked teams left to play, with this week's Vanderbilt matchup potentially ending up as a play-in game to the CFP. With the level Young and Missouri's defense are playing at right now, I think the Tigers can come up on top against Diego Pavia and Co.
One thing is clear: the best plus-money CFP bet is an SEC team; it's just a matter of backing the right one. Whether it's Missouri, Oklahoma (+225), or Vanderbilt (+500), it's hard to imagine one of those three not ending up in, if not two of them. It seems more likely that five SEC teams get in than two ACC or Big 12 programs.
Just don't bet Texas (+165) after Kentucky dragged the Longhorns to OT and Arch Manning put together another performance that would have you thinking he's a long-lost member of Tate Martell's family, not the latest QB from the first family of football.
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