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Kansas Jayhawks quarterback Jalon Daniels throws a pass against the UNLV Rebels.
Kansas Jayhawks quarterback Jalon Daniels throws a pass against the UNLV Rebels. Photo by Jay Biggerstaff via Imagn Images.

The Big 12 season officially begins this weekend, and a quick look at the odds for this slate illustrates why this conference will be so entertaining all year.

The largest spread for Saturday’s Big 12 slate is 6.5 points, with five of the six games having a line of 3.5 points or fewer.

Any team can win on any given week, setting the stage for a season of chaos as several teams eye the conference title game in Arlington, Texas. We see that reflected in the Big 12 Championship odds, too, with plenty of contenders toward the top of the oddsboard.

As part of our Week 4 college football predictions, our Big 12 predictions make the most of that chaos by betting against certainty after non-conference play.

Big 12 best bets: Week 4

College football odds as of Friday and subject to change. Track the college football scores for the latest line movement and matchup info.

Best Big 12 predictions this week

College football picks made Friday; odds subject to change. Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Kansas moneyline (+114) ⭐⭐⭐⭐

Kansas entered the year with high hopes as a ranked team with a potential path to the Big 12 title game. After back-to-back losses to Illinois and UNLV, KU fans are ready to hit the panic button.

But it’s worth noting how unlucky the Jayhawks have been.

According to SP+, KU’s postgame win expectancy was 87% against UNLV and 58% in a road meeting with Illinois. Both games came down to the very end after several mistakes by Kansas.

With a clean slate, the Jayhawks are in a good position to bounce back at West Virginia. The Mountaineers are also 1-2 following losses to Penn State and Pittsburgh, surrendering 72 combined points in those defeats.

This is where KU’s offense gets back on track, so the market has pushed its moneyline price to as short as +105. A $10 bet nets a $11.40 payout by placing this wager at DraftKings.

Best odds: +114 via DraftKings | Implied probability: 46.73%

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Jalon Daniels Over 28.5 rushing yards ⭐⭐⭐⭐⭐

The stock has never been lower on Kansas quarterback Jalon Daniels, who was once viewed as a Heisman Trophy odds dark horse.

Daniels has been the main reason for KU’s recent defeats, throwing six interceptions this season.

As evidenced by my first pick, I believe Daniels will rebound against a shaky WVU defense. While his passing props are enticing, I’m more interested in a low rushing line at FanDuel.

Daniels has cleared this line in back-to-back games, recording 100 yards on 21 attempts. Only five of those attempts have been credited as scrambles by PFF, illustrating that new offensive coordinator Jeff Grimes wants to use Daniels in the run game.

Best odds: -114 via FanDuel | Implied probability: 53.27%

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Baylor moneyline (+105) ⭐⭐⭐

Colorado (2-1) returns to the Big 12 by welcoming Baylor (2-1) to town.

While I think the Buffaloes will succeed more in league play, it’s worth reflecting on what they did when they stepped up in class last year. Colorado went 1-8 against Pac-12 opponents, often appearing overmatched in the trenches.

Dave Aranda’s Bears rank seventh in the country in EPA per play allowed on defense, which includes a 23-12 loss to Utah. He will have the Bears ready to stifle Shedeuer Sanders and Co., which is why the market has pushed this moneyline price tag down from +110.

Best odds: +105 via BetMGM | Implied probability: 48.78%

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More Big 12 predictions for Week 4

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