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SUNRISE, FLORIDA - MARCH 30: Jonathan Huberdeau #11 of the Florida Panthers skates against the Detroit Red Wings at the BB&T Center on March 30, 2021 in Sunrise, Florida. Bruce Bennett/Getty Images/AFP (Photo by BRUCE BENNETT / GETTY IMAGES NORTH AMERICA / Getty Images via AFP)

The Florida Panthers are undefeated after five games. Can the Boston Bruins hand them their first loss on Wednesday night?

Florida and Boston meet in a clash between two Atlantic Division rivals on Wednesday night. The Panthers (5-0 straight up, 2-3 Over/Under) hope to stay undefeated against another tough team in the Bruins (3-1 SU, 2-2 O/U).

Here are my picks and predictions for Wednesday’s NHL matchup between the Bruins and the Panthers (odds via Draftkings Sportsbook).

Bruins vs. Panthers Game Info

Date/Time: Wednesday, October 27, 7 p.m. ETTV: NHLN, TVAS, BSFL, NESNLocation: FLA Live Arena, Sunrise, FL

Bruins vs. Panthers Odds Analysis

The Panthers are home favorites at -130 on the moneyline and -1.5 (+190) on the puck line. The Bruins are underdogs for the first time this season at +110 on the moneyline and +1.5 (-235) on the puck line.

The total for this contest is set lower at 5.5 goals (Over -120, Under +100).

Bruins vs. Panthers Betting Picks

Florida Panthers (-130) ????Over 5.5 Goals (-120) ????

Bruins vs. Panthers Predictions

Florida Panthers (-130)

We’re riding the hot hand here. The Panthers have outscored their opponents 27-12, an average of 4.5 goals for and 2.0 goals against per game.

They’ve also beaten some of the league's better teams. The Cats bested the Penguins in overtime before rattling off multi-goal wins over the Islanders, Lightning, Avalanche, Flyers, and Coyotes. They posted a combined score of 13-3 over games against the Islanders, Lightning, and Avalanche 13-3.

The Bruins are also playing well at 3-1-0. However, their wins came as huge favorites against the Stars, Sabres, and Sharks. They barely squeaked out a 4-3 win over the Sharks as nearly -220 favorites.

The Panthers are looking like one of the NHL's top teams, if not the best. They’re at home with good value as just -130 favorites.

Over 5.5 Goals (-120)

Both of these teams have been scoring often this season. The Panthers are tied for the third-most goals per game with 4.5, while the Bruins sit tied for the ninth-most with 3.5.

The output from each club has been consistent too. The Bruins have scored three-plus goals in all four games this season, while the Panthers have done one better with four-plus goals in all five of their games.

The only concern with the Over is the Panthers shutting down the Bruins, as they're allowing two just goals per game. However, it’s worth taking that chance due to the quality of Boston's top-six forwards and Florida's strong start. These are two of the league's highest-paced offenses, and the Panthers and Bruins should combine to hit the Over.

In fact, look for a Panthers to win and over 5.5 goals parlay at +185 odds.

Picks made 10/27/2021 at 2:40 a.m. ET