49ers vs. Rams Touchdown Pick: Best TD Scorer Predictions For TNF
The 49ers and Rams kick off the 2026 NFL season Thursday night in a historic matchup at the Melbourne Cricket Ground in Australia. The game is scheduled for 8:35 p.m. ET and will stream live on Netflix. With plenty of star power on both sides, our top 49ers vs. Rams touchdown scorer pick is Rams wide receiver Davante Adams.
Adams enters the season as one of Matthew Stafford’s most trusted targets and has the experience and red-zone ability to find the end zone in this high-profile NFC West showdown.
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🏈 49ers vs. Rams touchdown scorer prediction: NFL Week 1
See the latest NFL odds and our experts' NFL picks for every game this season.
| 💰 Pick | 📊 Best odds | ⚖️ Units |
|---|---|---|
| Davante Adams | +120 via FanDuel | 1u → 1.2u |
Total wagered: 1 unit | Max profit: 1.2 units
💰 49ers vs. Rams best touchdown bet
Davante Adams is our top touchdown scorer pick for tonight’s 49ers vs. Rams matchup. Adams enters the season with tremendous red-zone upside after leading the NFL with 14 touchdown receptions last year. His chemistry with Matthew Stafford became especially dangerous during the second half of the 2025 season, when Adams scored 11 of his 14 touchdowns from Week 7 onward.
He also found the end zone against San Francisco in the Rams’ 42-26 victory last season. With Puka Nacua potentially limited, Adams could see an even larger target share, making him an excellent bet to score tonight.
📊 49ers vs. Rams odds: NFL Week 1
🚑 49ers vs. Rams latest injuries
📺 How to watch 49ers vs. Rams: NFL Week 1
- Date: Thursday, Sept. 10
- Kickoff: 8:35 p.m. ET
- Location: Melbourne Cricket Ground (MCG), Melbourne, Australia
- TV: Netflix
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