March Madness First Round Schedule & Live Odds: 2025 NCAA Tournament Game Info

Last updated: March 21, 2025 4:03 PM EDT • 4 min read X Social Google News Link

The most exciting three weeks in sports got underway yesterday afternoon, as March Madness has officially entered your living room. Auburn is the No. 1 seed entering the tournament, while Duke is the March Madness odds betting favorite.
While the March Madness bracket will be front and center for the duration of the tournament, here's the March Madness first-round schedule and opening odds, complete with game times and TV schedule.
Our C Jackson Cowart asked ChatGPT to fill out a March Madness bracket with a predicted score for every game.
🗓️ March Madness first round schedule
Here is the full March Madness first-round schedule with the NCAA Tournament beginning in full on Thursday. Listed odds are from BetMGM.
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👉 See all of the college basketball odds from our best March Madness betting sites.
🏀 March Madness odds & predictions for Friday
Here are Friday's March Madness odds:
No. 16 Norfolk State vs. No. 1 Florida odds, 6:50 p.m. ET
- When: Friday, March 21 | 6:50 p.m. ET
- Where: Lenovo Center (Raleigh, N.C.)
- How to watch: TNT
No. 14 Troy vs. No. 3 Kentucky odds, 7:10 p.m. ET
- When: Friday, March 21 | 7:10 p.m. ET
- Where: Fiserv Forum (Milwaukee)
- How to watch: CBS
No. 10 New Mexico vs. No. 7 Marquette odds, 7:25 p.m. ET
- When: Friday, March 21 | 7:25 p.m. ET
- Where: Rocket Arena (Cleveland)
- How to watch: TBS
No. 13 Akron vs. No. 4 Arizona odds, 7:35 p.m. ET
- When: Friday, March 21 | 7:35 p.m. ET
- Where: Climate Pledge Arena (Seattle)
- How to watch: truTV
No. 9 Oklahoma vs. No. 8 UConn odds, 9:25 p.m. ET
- When: Friday, March 21 | 9:25 p.m. ET
- Where: Lenovo Center (Raleigh, N.C.)
- How to watch: TNT
No. 11 Xavier vs. No. 6 Illinois odds, 9:45 p.m. ET
- When: Friday, March 21 | 9:45 p.m. ET
- Where: Fiserv Forum (Milwaukee)
- How to watch: CBS
No. 15 Bryant vs. No. 2 Michigan State odds, 10 p.m. ET
- When: Friday, March 21 | 10 p.m. ET
- Where: Rocket Arena (Cleveland)
- How to watch: TBS
No. 12 Liberty vs. No. 5 Oregon odds, 10:10 p.m. ET
- When: Friday, March 21 | 10:10 p.m. ET
- Where: Climate Pledge Arena (Seattle)
- How to watch: truTV
⏰ When is March Madness Round 1?
The first round of the 2025 NCAA Tournament takes place over Thursday and Friday with 16 games each day.
The First Four games will be played Tuesday and Wednesday, with two games each day. The second round of March Madness will begin Saturday with eight games played on each of Saturday and Sunday.
💰 March Madness betting odds pages
March Madness odds | March Madness MVP odds |
Women's March Madness odds | March Madness MVP predictions |
Final Four odds | March Madness prop bets |
👑 Best March Madness betting sites
Ready to place your March Madness bets? Check out the best March Madness betting promos from the best March Madness betting sites, as determined by our expert team at Sportsbook Review.
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Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission

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