CFL Division Semifinals Best Bets: Top Picks Against the Spread This Week
Last Updated: October 30, 2026 12:00 PM EDT • 3 minute read X Social Google News Link
The playoffs kick off Saturday, and my CFL division semifinals best bets back both home teams to win by margin.
The Blue Bombers visit the Argonauts in the East semifinal, with kickoff set for 1 p.m. ET. The Argonauts are a 3.5-point betting favorite, and the total is set at 57.5. In the West, the Lions host the Roughriders, with kickoff set for 4:30 p.m. ET. The Lions enter as a 6.5-point betting favorite, with the total set at 58.5.
CFL division semifinals best bets
See the latest CFL odds and our experts' CFL picks.
| Matchup | Pick | Units |
|---|---|---|
| Blue Bombers vs. Argonauts | Argonauts -3.5 (-114 via FanDuel) | 1.14 units to profit 1 unit |
| Roughriders vs. Lions | Lions -6.5 (-110 via DraftKings) | 2.2 units to profit 2 units |
Picks submitted: Oct. 29 at 3:56 p.m. ET. Odds subject to change.
Total wagered: 3.34 units | Max profit: 3 units
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Best CFL bet this week
Roughriders vs. Lions prediction: Lions -6.5 (-110)
The defending champion Roughriders have the longest Grey Cup odds at +1300, while the Lions have the third-shortest at +370. Despite that, I still believe the Lions are being underrated by the market.
The Lions rank second in the CFL with 418.4 yards per game, just behind the Alouettes, the Grey Cup favorite, and that was with last season's Most Outstanding Player, Nathan Rourke, missing multiple weeks. Since Rourke returned from injury in Week 10, excluding the final game of the season when he rested, the Lions have gone 8-2 straight up, with a +7 average scoring margin.
⏰️ Set your alarm: Roughriders vs. Lions
- Date: Saturday, Oct. 31
- Kickoff: 4:30 p.m. ET
- How to watch: TSN, CFL+
| Roughriders | Lions | |
|---|---|---|
| Spread | +7.5 (-117 via Pinnacle) | -6.5 (-110 via DraftKings) |
| Moneyline | +275 via BetMGM | -298 via DraftKings |
| Total | Over 57.5 (-115 via BetRivers) | Under 58.5 (-105 via Hard Rock Bet) |
More CFL picks for division semifinals
Blue Bombers vs. Argonauts prediction: Argonauts -3.5 (-114)
Zach Collaros' status is still unknown as of publication, as he's dealing with a rib injury. However, my read on this game is based on Collaros being doubtful to play, as he practiced for the first time this week Thursday and was limited.
The Argonauts were a 2-point road favorite against Dru Brown in Week 6 and a 1-point road underdog against Brown in Week 17. Using the Week 17 line as my starting point and then accounting for home-field advantage, I expect the Argonauts to close as a 5.5-point favorite if Collaros is ruled out, which is why I like -3.5 (-114).
However, there's no guarantee that Collaros will be ruled out, so I'm risking fewer units on this bet than on Lions -6.5 (-110).
⏰️ Set your alarm: Blue Bombers vs. Argonauts
- Date: Saturday, Oct. 31
- Kickoff: 1 p.m. ET
- How to watch: TSN, CFL+
| Blue Bombers | Argonauts | |
|---|---|---|
| Spread | +5.5 (-115 via DraftKings) | -3.5 (-114 via FanDuel) |
| Moneyline | +195 via DraftKings | -210 via FanDuel |
| Total | Over 57.5 (-106 via Pinnacle) | Under 58.5 (-112 via BetRivers) |
My betting record for CFL picks
CFL picks have been tracked since June 4.
| Bet type | Record | Net profit | ROI |
|---|---|---|---|
| Overall | 35-30-1 | +11.55 units | 12.2% |
| Moneyline | 1-0 | +2 units | 100% |
| Spread | 22-14-1 | +12.35 units | 16% |
| Total | 12-16 | -2.8 units | -18.3% |
Corey Scott X social